Classes
DEA Class; Rx
Common Brand Names; Polytrim Ophthalmic Solution
- Antibiotics, Ophthalmic Combos
Description
Ophthalmic preparation for the treatment of acute bacterial ocular infections; Polymyxin B has activity against gram-negative aerobic bacteria, including P. aeruginosa; trimethoprim is effective against both gram-positive and gram-negative organisms.
Indications
Indicated in the treatment of surface ocular bacterial infections, including acute bacterial conjunctivitis and blepharoconjunctivitis
Contraindications
Hypersensitivity
Adverse Effects
Local irritation consisting of increased redness, burning, stinging, and/or itching
Hypersensitivity reactions consisting of lid edema, itching, increased redness, tearing, and/or circumocular rash
Warnings
Not for injection into the eye
Not indicated for prophylaxis or treatment of ophthalmia neonatorum
Prolonged use may result in overgrowth of nonsusceptible organisms
Avoid contaminating applicator tip with material from the eye, fingers, or other source
If redness, irritation, swelling or pain persists or increases, discontinue use immediately and seek medical attention
Advise patient to not to wear contact lenses with active signs and symptoms of ocular bacterial infections or while using antibacterial eyedrops
Pregnancy and Lactation
Pregnancy Category: C
Lactation: Unknown whether distributed in breast milk
Maximum Dosage
6 drops/day.
6 drops/day.
6 drops/day.
6 drops/day.
>= 2 months: 6 drops/day.
< 2 months: Use not established.
How supplied
Trimethoprim/polymyxin B
ophthalmic solution
- (1mg/10,000 units)/mL