KAPS exam sample Material Test 2 Paper 1

KAPS exam sample Material Test 2 Paper 1

This KAPS Quiz contains older questions to help you practise. These questions are no longer used, but they’ll help you understand:

  • the types of content covered in each paper of the exam
  • how questions might be presented

If you want to practise the sample papers under exam conditions, you’ll need to answer all 100 questions in each paper in 2 hours.

KAPS Exam scoring

You must complete all questions in the paper or papers you sit.

To pass the exam, you need a mark of at least 50% in all subsections of the exam.

Paper 1Pharmaceutical chemistry 50%
Pharmacology and physiology 50%
Paper 2Pharmaceutics 50%
Therapeutics 50%

Here is the Test 2 Paper 1

Section 1 = 30 Questions

Section 2 = 70 Questions

Section 1

Trimeprazine belongs to the group of drugs known as:

Correct! Wrong!

Techniques involving polymerase chain reaction (PCR) can be used to identify all of the following EXCEPT

Correct! Wrong!

The antibacterial action of a sulphonamide, resulting from its blocking bacterial uptake of p-amino-benzoic acid (PABA) is due to the presence of

Correct! Wrong!

To have useful antibacterial activity, a sulphonamide molecule must possess or be capable of conversion in the body into which ONE of the following?

Correct! Wrong!

When dimercaprol (B.A.L.) is used to treat heavy metal poisoning, its effectiveness is due to the chelate formed being all the following EXCEPT:

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The chemical bond connecting amino acids in the primary structure of proteins is

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Conformational isomerism is described as

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Which substance yields the largest number of joules per gram?

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The term which describes the time required for the radioactivity of any given amount of a drug to be reduced by 50 percent is:

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One property that phenytoin, phenobarbitone and rifampicin all have in common is that they

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The gamma radiation from radioactive vitamin B12 comes from the:

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Temazepam, which has the structure below, would MOST probably undergo:

Drugsace.com Test 2 a 1
I. direct conjugation with glucuronic acid II. deesterification III. N-dealkylation
Show hint
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Which of the following is TRUE for the hypnotic drug temazepam?

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The various penicillins that are available differ chemically

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The chemical class of the compound Below is

Drugsace.com Test 2 b 1
Correct! Wrong!

Which one of the following acids is polyunsaturated?

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Conformation of organic molecules is MOST commonly determined by which ONE of the following analytical methods?

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Oleic acid exists in the cis form. This means:

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Quinine sulphate

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Which of the following compounds contains either an aldehydic or a ketonic functional group?

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Lignocaine HCl can be infused intravenously and remain stable for long enough to have a therapeutic effect because it

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Sodium lauryl sulfate is incompatible with

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Sulphonamides differ chemically in substitutions that are made on a fundamental structure common to all. That structure is

Drugsace.com Test 2 i
Drugsace.com Test 2 ii
Drugsace.com Test 2 iii
Drugsace.com Test 2 iv
Correct! Wrong!

A potential therapeutic use for 1,3-dimethylxanthine is as a(an):

Drugsace.com Test 2 c 1
Correct! Wrong!

The metabolism of drugs generally results in

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Which ONE of the following does the chemical structure given above represent?

Drugsace.com Test 2 d 1
Correct! Wrong!

Which of the following statements is TRUE?

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Reagent strips impregnated with glucose oxidase, peroxidase, and orthotolidine are dipped into urine or blood as a test for the presence of glucose.

The reaction(s) that occur are:
Show hint
Correct! Wrong!

An aqueous solution of the sodium salt of an antibacterial sulphonamide would be

Correct! Wrong!

Glimepiride exerts its hypoglycaemic action by

Correct! Wrong!

The KAPS (Knowledge Assessment of Pharmaceutical Sciences) Exam Tests 2 Paper 1 Section 1
Result
Paper 2 Section 1 Pharmaceutical Chemistry Passing Score 50% FAIL
Result
Paper 2 Section 1 Pharmaceutical Chemistry Passing Score 50% PASS

Section 2

Section 1 Completed

Section 2

The therapeutic action of allopurinol in gout is due to its effect of

Correct! Wrong!

Which of the following is LEAST likely to exacerbate seizures?

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Atropine

Correct! Wrong!

Which ONE of the following is associated with gingival hyperplasia after long-term treatment?

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Which ONE of the following statements is CORRECT?

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All of the following statements about warfarin are correct EXCEPT for:

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Parathyroid hormone has which ONE of the following effects?

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Which ONE of the following is NOT recognized as a central neurotransmitter?

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Levodopa is often the drug of choice in the treatment of parkinsonism. The rationale for the use of this drug is based upon which of the following?

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Acne vulgaris:

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Which of the following is predominately excreted as an unchanged drug

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The term "pure opioid antagonist" most appropriately applies to which ONE of the following?

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The doses of clomiphene citrate, which is used in the treatment of infertility, should be taken on which of the following days of the menstrual cycle?

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What is the principal way that glyceryl trinitrate relieves the symptoms of angina pectoris?

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Which ONE of the following medicines is an alternative to aminoglycosides for antibiotic prophylaxis in urological surgery?

Correct! Wrong!

The conjugation of bilirubin occurs mainly in which ONE of the following?

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Which ONE of the following statements about dose and response is CORRECT?

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Which ONE of the following statements is CORRECT with respect to congestive heart failure (CHF)?

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The cause of death in acute paracetamol overdose is due to the accumulation of toxic metabolites resulting in:

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Cyproheptadine can BEST be classified pharmacologically as a(an):

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ß-adrenergic agonists exert an inotropic effect on the myocardium because they:

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Which ONE of the following has the HIGHEST incidence in young women?

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In regard to urinary tract infections (UTIs) the following statements are true EXCEPT for:

Correct! Wrong!

Which ONE of the following is the major determinant of myocardial oxygen consumption?

Correct! Wrong!

Tinnitus, headache, nausea, and sweating are symptoms of which ONE of the following?

Correct! Wrong!

Why is allopurinol used for the treatment of gout?

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Which ONE of the following steroids has markedly different physiological properties to the other four?

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Of the following agents, the one which possesses the greatest degree of antihistaminic action is

The reaction(s) that occur are:
Show hint
Correct! Wrong!

Which ONE of the following is NOT a side effect of amitriptyline?

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Which ONE of the following antiepileptic drugs has activity against both generalised tonic-clonic seizures and generalised absence seizures?

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Mebendazole, a benzimidazole derivative used for the treatment of worm infestations, functions by

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Which ONE of the following describes a person with normal thyroid function?

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The pharmacological effects of sumatriptan arise from its ability to:

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Which ONE of the following parasites CANNOT infect both animals and man?

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What is the range for the daily recommended allowance of calcium for women?

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Quetiapine is an atypical antipsychotic similar to clozapine, but unlike clozapine it does have significant antagonist activity at which one of the following receptors?

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Which one of the following statements is TRUE?

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Chronic iodine deficiency during adult life results in which ONE of the following conditions?

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Which ONE of the following is NOT a feature of psoriasis?

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Phenytoin:

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Symptoms of atropine poisoning include all of the following EXCEPT:

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Ketorolac:

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Immediate or anaphylactic hypersensitivity:

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Cough receptors are present in which ONE of the following?

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Each of the following is a major determinant of myocardial oxygen demand EXCEPT for:

Correct! Wrong!

Miosis is:

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In which ONE of the following drugs is the pharmacological activity associated with optical isomers?

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Which one of the following eye drops causes rapid mydriasis and has a duration effect of only 2 to 3 hours?

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Which ONE of the following statements concerning fats and carbohydrates is MOST appropriate? Fats and carbohydrates:

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Emphysema:

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All of the following statements regarding tyramine are true EXCEPT

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Which type of vitamin is MOST toxic above the tolerable upper limit?

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Discarding outdated or improperly stored tetracyclines is especially important because they may:

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Two drugs may act on the same tissue or organ through independent receptors, resulting in effects in opposite directions. What is this known as?

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Digoxin

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All of the following are features of hypoglycaemia EXCEPT for:

Correct! Wrong!

Cardiac glycosides increase the force of contraction by

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Cephalosporins typically covers all strains of streptococci EXCEPT for:

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Of the following, which adverse reaction is NOT associated with frusemide?

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Propranolol could be used in the management of the following conditions EXCEPT for:

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Following shock, intravenous sodium bicarbonate is used to:

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The intrinsic activity or efficacy of a drug is

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Which ONE of the following is a penicillin which is effective in the presence of penicillinase?

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Which ONE of the following is characterized by excess secretion of thyroid hormone?

Correct! Wrong!

The pain associated with angina pectoris is caused by which ONE of the following?

Correct! Wrong!

Simvastatin is effective in lowering:

Drugsace.com Test 2 Case 1
Correct! Wrong!

Use of the antiarrhythmic prescribed on September 30 is limited because of which ONE of the following side effects?

Drugsace.com Test 2 Case 1
Correct! Wrong!

Which ONE of the following should be regularly monitored for amiodarone toxicity?

Drugsace.com Test 2 Case 1
Correct! Wrong!

Mr Piper complains of bilateral shoulder and hip muscle pain. Which ONE of the following tests is MOST appropriate to investigate his symptoms?

Drugsace.com Test 2 Case 1
Correct! Wrong!

Which ONE of Mr Piper's medications is MOST likely to be implicated in his muscle pain?

Drugsace.com Test 2 Case 1
Correct! Wrong!

The KAPS (Knowledge Assessment of Pharmaceutical Sciences) Exam Tests 2 Paper 1 Section 2
Result
Paper 2 Section 1 Physiology and Pharmacology Passing Score 50%rnrnFAILrn
Result
Paper 2 Section 1 Physiology and Pharmacology Passing Score 50%rnrnPASSrn
Section 2 Completed

KAPS Exam Guide

1 Comment
  1. Great job!! Really appreciated.

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