This KAPS Quiz contains older questions to help you practise. These questions are no longer used, but they’ll help you understand:
- the types of content covered in each paper of the exam
- how questions might be presented
If you want to practise the sample papers under exam conditions, you’ll need to answer all 100 questions in each paper in 2 hours.
Paper 1 | Pharmaceutical chemistry 50% Pharmacology and physiology 50% |
Paper 2 | Pharmaceutics 50% Therapeutics 50% |
Here is the Test 2 Paper 1
Section 1 = 30 Questions
Section 2 = 70 Questions
Section 1
Trimeprazine belongs to the group of drugs known as:
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Techniques involving polymerase chain reaction (PCR) can be used to identify all of the following EXCEPT
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The antibacterial action of a sulphonamide, resulting from its blocking bacterial uptake of p-amino-benzoic acid (PABA) is due to the presence of
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To have useful antibacterial activity, a sulphonamide molecule must possess or be capable of conversion in the body into which ONE of the following?
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When dimercaprol (B.A.L.) is used to treat heavy metal poisoning, its effectiveness is due to the chelate formed being all the following EXCEPT:
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The chemical bond connecting amino acids in the primary structure of proteins is
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Conformational isomerism is described as
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Which substance yields the largest number of joules per gram?
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The term which describes the time required for the radioactivity of any given amount of a drug to be reduced by 50 percent is:
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One property that phenytoin, phenobarbitone and rifampicin all have in common is that they
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The gamma radiation from radioactive vitamin B12 comes from the:
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Temazepam, which has the structure below, would MOST probably undergo:
1
I. direct conjugation with glucuronic acid
II. deesterification
III. N-dealkylation
Show hint
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Which of the following is TRUE for the hypnotic drug temazepam?
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The various penicillins that are available differ chemically
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The chemical class of the compound Below is
1
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Which one of the following acids is polyunsaturated?
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Conformation of organic molecules is MOST commonly determined by which ONE of the following analytical methods?
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Oleic acid exists in the cis form. This means:
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Quinine sulphate
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Which of the following compounds contains either an aldehydic or a ketonic functional group?
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Lignocaine HCl can be infused intravenously and remain stable for long enough to have a therapeutic effect because it
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Sodium lauryl sulfate is incompatible with
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Sulphonamides differ chemically in substitutions that are made on a fundamental structure common to all. That structure is
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A potential therapeutic use for 1,3-dimethylxanthine is as a(an):
1
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The metabolism of drugs generally results in
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Which ONE of the following does the chemical structure given above represent?
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Which of the following statements is TRUE?
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Reagent strips impregnated with glucose oxidase, peroxidase, and orthotolidine are dipped into urine or blood as a test for the presence of glucose.
The reaction(s) that occur are:
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An aqueous solution of the sodium salt of an antibacterial sulphonamide would be
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Glimepiride exerts its hypoglycaemic action by
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The KAPS (Knowledge Assessment of Pharmaceutical Sciences) Exam Tests 2 Paper 1 Section 1
Result
Paper 2 Section 1 Pharmaceutical Chemistry Passing Score 50%
FAIL
Result
Paper 2 Section 1 Pharmaceutical Chemistry Passing Score 50%
PASS
Section 2
Section 1 Completed
Section 2
The therapeutic action of allopurinol in gout is due to its effect of
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Which of the following is LEAST likely to exacerbate seizures?
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Atropine
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Which ONE of the following is associated with gingival hyperplasia after long-term treatment?
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Which ONE of the following statements is CORRECT?
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All of the following statements about warfarin are correct EXCEPT for:
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Parathyroid hormone has which ONE of the following effects?
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Which ONE of the following is NOT recognized as a central neurotransmitter?
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Levodopa is often the drug of choice in the treatment of parkinsonism. The rationale for the use of this drug is based upon which of the following?
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Acne vulgaris:
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Which of the following is predominately excreted as an unchanged drug
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The term "pure opioid antagonist" most appropriately applies to which ONE of the following?
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The doses of clomiphene citrate, which is used in the treatment of infertility, should be taken on which of the following days of the menstrual cycle?
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What is the principal way that glyceryl trinitrate relieves the symptoms of angina pectoris?
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Which ONE of the following medicines is an alternative to aminoglycosides for antibiotic prophylaxis in urological surgery?
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The conjugation of bilirubin occurs mainly in which ONE of the following?
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Which ONE of the following statements about dose and response is CORRECT?
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Which ONE of the following statements is CORRECT with respect to congestive heart failure (CHF)?
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The cause of death in acute paracetamol overdose is due to the accumulation of toxic metabolites resulting in:
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Cyproheptadine can BEST be classified pharmacologically as a(an):
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ß-adrenergic agonists exert an inotropic effect on the myocardium because they:
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Which ONE of the following has the HIGHEST incidence in young women?
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In regard to urinary tract infections (UTIs) the following statements are true EXCEPT for:
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Which ONE of the following is the major determinant of myocardial oxygen consumption?
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Tinnitus, headache, nausea, and sweating are symptoms of which ONE of the following?
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Why is allopurinol used for the treatment of gout?
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Which ONE of the following steroids has markedly different physiological properties to the other four?
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Of the following agents, the one which possesses the greatest degree of antihistaminic action is
The reaction(s) that occur are:
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Which ONE of the following is NOT a side effect of amitriptyline?
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Which ONE of the following antiepileptic drugs has activity against both generalised tonic-clonic seizures and generalised absence seizures?
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Mebendazole, a benzimidazole derivative used for the treatment of worm infestations, functions by
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Which ONE of the following describes a person with normal thyroid function?
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The pharmacological effects of sumatriptan arise from its ability to:
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Which ONE of the following parasites CANNOT infect both animals and man?
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What is the range for the daily recommended allowance of calcium for women?
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Quetiapine is an atypical antipsychotic similar to clozapine, but unlike clozapine it does have significant antagonist activity at which one of the following receptors?
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Which one of the following statements is TRUE?
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Chronic iodine deficiency during adult life results in which ONE of the following conditions?
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Which ONE of the following is NOT a feature of psoriasis?
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Phenytoin:
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Symptoms of atropine poisoning include all of the following EXCEPT:
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Ketorolac:
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Immediate or anaphylactic hypersensitivity:
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Cough receptors are present in which ONE of the following?
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Each of the following is a major determinant of myocardial oxygen demand EXCEPT for:
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Miosis is:
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In which ONE of the following drugs is the pharmacological activity associated with optical isomers?
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Which one of the following eye drops causes rapid mydriasis and has a duration effect of only 2 to 3 hours?
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Which ONE of the following statements concerning fats and carbohydrates is MOST appropriate? Fats and carbohydrates:
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Emphysema:
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All of the following statements regarding tyramine are true EXCEPT
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Which type of vitamin is MOST toxic above the tolerable upper limit?
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Discarding outdated or improperly stored tetracyclines is especially important because they may:
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Two drugs may act on the same tissue or organ through independent receptors, resulting in effects in opposite directions. What is this known as?
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Digoxin
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All of the following are features of hypoglycaemia EXCEPT for:
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Cardiac glycosides increase the force of contraction by
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Cephalosporins typically covers all strains of streptococci EXCEPT for:
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Of the following, which adverse reaction is NOT associated with frusemide?
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Propranolol could be used in the management of the following conditions EXCEPT for:
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Following shock, intravenous sodium bicarbonate is used to:
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The intrinsic activity or efficacy of a drug is
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Which ONE of the following is a penicillin which is effective in the presence of penicillinase?
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Which ONE of the following is characterized by excess secretion of thyroid hormone?
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The pain associated with angina pectoris is caused by which ONE of the following?
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Simvastatin is effective in lowering:
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Use of the antiarrhythmic prescribed on September 30 is limited because of which ONE of the following side effects?
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Which ONE of the following should be regularly monitored for amiodarone toxicity?
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Mr Piper complains of bilateral shoulder and hip muscle pain. Which ONE of the following tests is MOST appropriate to investigate his symptoms?
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Which ONE of Mr Piper's medications is MOST likely to be implicated in his muscle pain?
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The KAPS (Knowledge Assessment of Pharmaceutical Sciences) Exam Tests 2 Paper 1 Section 2
Result
Paper 2 Section 1 Physiology and Pharmacology Passing Score 50%rnrnFAILrn
Result
Paper 2 Section 1 Physiology and Pharmacology Passing Score 50%rnrnPASSrn
Great job!! Really appreciated.