Tag: Trypanosomiasis

Brands Classes DEA Class; Rx Common Brand Names; Suramin sodium Antiprotozoal Agents Description Trypanocidal activity; inhibits enzymes involved with the oxidation of reduced NADH Indications Indicated for  Trypanosomiasis TB Gambiense Treatment of hormone-refractory prostate cancer Contraindications Hypersensitivity Adverse Effects Vomiting Urticaria Paresthesia Peripheral neuropathy Kidney damage Blood dyscrasias Polyuria Polydipsia Pancytopenia Shock Optic atrophy Warnings Proteinuria…

Brands Classes DEA Class; Rx Common Brand Names; NebuPent, Pentam Antipneumocystis Agents Description Oral inhalation/IM/IV antifungal agentUsed for Pneumocystis jiroveci (Pneumocystis carinii) pneumonia treatment and prophylaxis Parenteral administration is associated with several major ADRs Indications Indicated for the treatment of Pneumocystis pneumonia (PCP).For pneumocystis pneumonia (PCP) prophylaxis.For the treatment of leishmaniasis.For the treatment of African trypanosomiasis (sleeping…

Brands Classes DEA Class; Rx Common Brand Names; Lampit Antiprotozoal Agents Description Antiprotozoal agent Mechanism of action is not fully understood May react with the nucleic acids of the parasite and inhibits trypanothione reductase, a parasite-specific antioxidant defense enzyme Indications Orphan designation for Chagas Disease (American Trypanosomiasis) Contraindications Hypersensitivity to nifurtimox or any of the excipients…

Brands Classes DEA Class; Rx Common Brand Names; Arsobal Antiprotozoal Agents Description Inhibits synthesis of ATP – the energy required for survival of the parasite Indications Indicated for the African Trypanosomiasis (Sleeping Sickness) Contraindications Glucose-6-phosphate dehydrogenase (G6PD) deficiency, hypersensitivity Adverse Effects Hypertension Myocardial damage Encephalopathy Peripheral neuropathy Colic Vomiting Albuminuria Herxheimer-type reaction Warnings — Pregnancy and…

Brands Classes DEA Class; Rx Common Brand Names; Ornidyl, Vaniqa Antiprotozoal Agents Topical Skin Products Description Antiprotozoal agentUsed topically to reduce unwanted facial hair in women and parenterally to treat African trypanosomiasis (sleeping sickness)In US only available as topical cream; IV only available from the WHO/CDC Indications Indicated for the reduction of unwanted facial hair in…

Brands Classes DEA Class; Rx Common Brand Names; Benznidazole Antiparasitic Agents Description AntiprotozoalUsed for the treatment of Chagas disease or American trypanosomiasis, a parasitic infection caused by Trypanosoma cruziOnly approved for pediatric patients 2 to 12 years, although used off-label in patients of all ages Indications Indicated for the treatment of American trypanosomiasis (Chagas disease). Contraindications…