Tag: Thrombolytic Agents

  • Tenecteplase

    Brands Classes DEA Class; Rx Common Brand Names; TNK tPA, TNKase Thrombolytics Description Recombinant thrombolytic agent given as single IV bolus for AMILonger half-life, increased fibrin specificity, and increased resistance to PAI-1 compared to alteplase with similar clinical outcomes of 30-day mortality, intracranial bleeding, and minor bleedingMajor (non-cerebral) bleeding and blood transfusions were lower with…

  • Alteplase

    Brands Classes DEA Class; Rx Common Brand Names; Activase, TPA, Cathflo Activase Thrombolytics Description Parenteral tissue plasminogen activator (tPA)Used for the treatment of acute ischemic stroke, acute myocardial infarction, and acute massive pulmonary embolism, and for the restoration of function to central venous access devicesAssociated with significant, sometimes fatal, internal or external bleeding   Indications Indicated…