Tag: Steroid Hormones and Their Antagonists

Brands Classes DEA Class; Rx Common Brand Names; Trelstar Depot, Triptodur, Trelstar, Trelstar LA Antineoplastics, GNRH Agonist Description Agonist analog of gonadotropin-releasing hormone (GnRH)Used for the palliative treatment of advanced prostate cancer and the treatment of central precocious pubertyDepression, including rare reports of suicidal ideation and attempt, has been reported with GnRH agonists in children treated…

Brands Classes DEA Class; Rx Common Brand Names; Femara Antineoplastics, Aromatase Inhibitor Description Nonsteroidal oral aromatase inhibitorUsed in postmenopausal women as adjuvant therapy for early breast cancer, extended adjuvant therapy after completion of 5 years of tamoxifen, and for advanced breast cancer; used off-label for infertility, idiopathic short stature in boys, and delayed puberty in…

Brands Classes DEA Class; Rx Common Brand Names; Faslodex Antineoplastics, Estrogen Receptor Antagonist Description Estrogen-receptor antagonist without any known estrogen agonist effectsUsed in postmenopausal women as monotherapy or in combination with ribociclib for first- and second-line treatment of HR-positive, HER2-negative advanced breast cancer, and in combination with palbociclib or abemaciclib in women with HR-positive, HER2-negative…

Brands Classes DEA Class; Rx Common Brand Names; Aromasin Antineoplastics, Aromatase Inhibitor Description Oral, irreversible, steroidal aromatase inhibitor for early breast cancer (estrogen-receptor positive after 2 to 3 years of tamoxifen therapy) or advanced breast cancerLacks cross-resistance with other aromatase inhibitors or tamoxifen; more complete estrogen blockade than anastrazole or letrozoleSimilar response rate to megestrol…

Brands Classes DEA Class; Rx Common Brand Names; Arimidex Antineoplastics, Aromatase Inhibitor Description Selective non-steroidal aromatase inhibitorUsed for the treatment of breast cancer in postmenopausal womenImproved disease-free survival compared with tamoxifen as adjuvant therapy for early breast cancer; overall survival was similar Indications Breast Cancer Adjuvant treatment Indicated for adjuvant treatment of postmenopausal women with…