DrugsAce

Tag: Protein Synthesis (Antibiobics)

  • Quinupristin/Dalfopristin

    Brands Classes DEA Class; Rx Common Brand Names; Synercid Streptogramins Description Streptogramin antibiotics isolated from Streptomyces pristinaespiralis. They act synergistically against susceptible bacteria when administered together. The combination has up to 16 times the activity of each agent alone. Used for vancomycin-resistant Enterococcus faecium bacteremia and for complicated skin and skin-structure infections due to Staphylococcus…

  • Chloramphenicol

    Brands Classes DEA Class; Rx Common Brand Names; Chloramphenicol IV, Chloromycetin Antibiotics, Other Description Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit; mainly bacteriostatic Indications Indicated for Serious Infections Caused by Susceptible Strains. Use only as alternative for treatment of meningitis, typhoid, or rickettsial infection Contraindications Hypersensitivity Oral or topical use Bacterial prophylaxis…

  • Tedizolid

    Brands Classes DEA Class; Rx Common Brand Names; Sivextro Oxazolidinones Description Oxazolidinone antibioticUsed for acute bacterial skin and skin structure infections (ABSSSI) caused by certain susceptible gram-positive bacteria in adults and pediatric patients 12 years and olderAs effective as linezolid for the treatment of ABSSSI; safety and efficacy not evaluated in patients with neutropenia Indications…

  • Linezolid

    Brands Classes DEA Class; Rx Common Brand Names; Zyvox Antibiotics, Other;  Oxazolidinones Description Synthetic oxazolidinone antibioticIndicated for treatment of bacterial pneumonia, skin and skin structure infections, and for vancomycin-resistant enterococcal (VRE) infections, including infections due to susceptible organisms which are complicated by bacteremiaInhibits MAO and may cause drug interactions with adrenergic and serotonergic drugs Indications…

  • Clindamycin

    Brands Classes DEA Class; Rx Common Brand Names; Cleocin, Cleocin Pediatric Antibiotics, Lincosamide clindamycin topical (Rx) Brand and Other Names: Cleocin T, Clindagel, Clindacin P, ClindaReach, ClindaDerm, ClindaMax, Clindets, Evoclin Classes: Acne Agents, Topical clindamycin vaginal (Rx) Brand and Other Names: Clindesse Vaginal Cream, Cleocin Vaginal Cream, Cleocin Vaginal Ovules, Xaciato Classes: Vaginal Preparations, Other Description Oral/parenteral/topical/vaginal antibiotic derived from lincomycinCommonly…

  • Fidaxomicin

    Brands Classes DEA Class; Rx Common Brand Names; Dificid Macrolides Description Oral macrolide antibiotic with minimal systemic absorptionUsed for Clostridium difficile-associated diarrhea (CDAD) in adults and pediatric patients 6 months and olderMay provide improved sustained response for CDAD Indications Indicated for treatment of Clostridioides difficile-associated diarrhea (CDAD) To reduce the development of drug-resistant bacteria and maintain…

  • Erythromycin

    Brands Classes DEA Class; Rx Common Brand Names; Ery-Tab, PCE Dispertab Macrolides erythromycin ophthalmic (Rx) Brand and Other Names:Ilotycin Ophthalmic Classes: Macrolides, Ophthalmic erythromycin topical (Rx) Brand and Other Names: AkneMycin, Ery Classes: Acne Agents, Topical;  Antibacterials, Topical erythromycin stearate (Rx) Brand and Other Names: Erythrocin Stearate Classes: Macrolides erythromycin lactobionate (Rx) Brand and Other Names: Erythrocin Lactobionate Classes: Macrolides erythromycin ethylsuccinate (Rx) Brand…

  • Clarithromycin

    Brands Classes DEA Class; Rx Common Brand Names; Biaxin, Biaxin XL Macrolides Description Oral macrolide antibiotic; penetrates lung tissue and macrophages to a greater degree than erythromycin; used for respiratory tract infections, STDs, otitis media, and MAC in AIDS patients; used in combination regimens for H. pylori eradication. Indications Indicated for treatment of mild-to-moderate infections…

  • Azithromycin

    Brands Classes DEA Class; Rx Common Brand Names; Zithromax Macrolides azithromycin ophthalmic (Rx) Brand and Other Names: AzaSite Classes: Macrolides, Ophthalmic   Description Macrolide antibiotic similar in structure to erythromycin, but can be dosed systemically once dailyUsed systemically for otitis media, pharyngitis, community-acquired pneumonia, sexually transmitted diseases, and Mycobacterium avium complex (MAC) prophylaxis and treatment in patients…

  • Tobramycin/Loteprednol

    Brands Classes DEA Class; Rx Common Brand Names; Zylet Antibiotics/Corticosteroids, Ophthalmic   Description Ophthalmic suspension of a corticosteroid (loteprednol) plus aminoglycoside antibiotic (tobramycin); indicated for steroid-responsive inflammatory conditions associated with superficial bacterial ocular infection or a risk thereof. Indications Indicated for steroid-responsive ocular inflammations with risk of superficial bacterial infections Shake vigorously before use Contraindications…

  • Tobramycin

    Brands Classes DEA Class; Rx Common Brand Names; Nebcin injection Aminoglycosides tobramycin ophthalmic (Rx) Brand and Other Names: Tobrex, Tobramycin Ophth, AKTob Classes: Aminoglycosides, Ophthalmic tobramycin inhaled (Rx) Brand and Other Names: TOBI, Bethkis, TOBI Podhaler, Kitabis Pak Classes: Aminoglycosides Description Parenteral, inhaled, or ophthalmic aminoglycoside antibioticMost active against aerobic gram-negative rodsRisk of ototoxicity and renal toxicity with high serum concentration…

  • Streptomycin

    Generic Only Classes DEA Class; Rx Common Brand Names;  Aminoglycosides   Description Aminoglycoside antibiotic; due to resistant organisms, increased risk of irreversible vestibular toxicity, and the inability to monitor serum concentration, other aminoglycoside agents are more desirable. Indications Indicated for the treatment of brucellosis in combination with other antimicrobials. Indicated for the treatment of gram-negative…

  • Neomycin/Polymyxin B/Gramicidin Ophthalmic

    Brands Classes DEA Class; Rx Common Brand Names; Gramicidin, Neosporin Ophthalmic Solution, Neocin-PG Antibiotics, Ophthalmic Combos   Description Aminoglycoside neomycin with polymyxin B and gramicidins A, B and COphthalmic preparation; used for ophthalmic bacterial infectionsCombination provides overlapping coverage against a wide range of gram-positive and gram-negative bacteria, including streptococci Indications Indicated for the treatment of superficial…

  • Neomycin

    Brands Classes DEA Class; Rx Common Brand Names; Neo-Fradin, Myciguent, Mycifradin Aminoglycosides   Description Aminoglycoside antibiotic derived from Streptomyces fradiae. Most often used topically as an antiinfective. Oral bioavailability is poor, but is administered orally in patients with hepatic coma or portal-systemic encephalopathy. Oral neomycin also has a lipid-lowering effect but is infrequently used for this…

  • Gentamicin

    Brands Classes DEA Class; Rx Common Brand Names;  Aminoglycosides gentamicin topical (Rx) Brand and Other Names: Garamycin topical Classes: Antibacterials, Topical gentamicin ophthalmic (Rx) Brand and Other Names: Garamycin Ophthalmic, Genoptic, Gentak Classes: Aminoglycosides, Ophthalmic Description Aminoglycoside antibioticUsed for a variety of gram-negative bacterial infections as well as synergistically for gram-positive bacterial infections, such as endocarditisMajor toxicities include nephrotoxicity, ototoxicity,…