Tag: Prostaglandin and Prostacyclin Analogs

  • Treprostinil

    Brands Classes DEA Class; Rx Common Brand Names; Remodulin, Orenitram PAH, Prostacyclin Analogs treprostinil inhaled (Rx) Brand and Other Names: Tyvaso, Tyvaso DPI Classes: PAH, Prostacyclin Analogs Description Analog of epoprostenol (prostacyclin) for treatment of pulmonary hypertension and pulmonary hypertension associated with interstitial lung diseaseGiven by inhalation (nebulizer solution or dry powder oral inhaler), continuous subcutaneous or…

  • Iloprost

    Brands Classes DEA Class; Rx Common Brand Names; Ventavis PAH, Prostacyclin Analogs Description Inhaled prostacyclin derivative; vasodilator; some systemic absorption with inhibition of platelet aggregation possibleAdministered via specific types of nebulizer machineImproves symptoms in patients with pulmonary arterial hypertension. Indications Indicated for the treatment of pulmonary hypertension to improve a composite endpoint consisting of exercise…

  • Epoprostenol

    Brands Classes DEA Class; Rx Common Brand Names; Flolan, Veletri PAH, Prostacyclin Analogs Description Pharmaceutical form of prostacyclin; vasodilator and an inhibitor of platelet aggregation; improves symptoms and prolongs survival in pulmonary hypertension. Indications Indicated for the treatment of pulmonary hypertension to improve exercise ability in persons with WHO Group 1 pulmonary hypertension. For acute…

  • Travoprost

    Brands Classes DEA Class; Rx Common Brand Names; Travatan, Travatan Z Antiglaucoma, Prostaglandin Agonists Description Topical ophthalmic agent; prodrug used to lower IOP in patients with open-angle glaucoma or ocular hypertension; synthetic analog of prostaglandin F2alpha; this drug is associated with iridal brown pigmentation similar to latanoprost. Indications Indicated for the reduction of elevated intraocular…

  • Tafluprost

    Brands Classes DEA Class; Rx Common Brand Names; Zioptan Antiglaucoma, Prostaglandin Agonists Description Prostaglandin analogUsed for reducing elevated IOP in patients with open-angle glaucoma or ocular hypertensionMay increase pigmentation of eyelashes, iris, and/or eyelid skin Indications Indicated for the reduction of increased intraocular pressure in patients with open-angle glaucoma or ocular hypertension.. Contraindications — Adverse…

  • Latanoprost

    Brands Classes DEA Class; Rx Common Brand Names; Xalatan, Xelpros, Iyuzeh Antiglaucoma, Prostaglandin Agonists Description Ophthalmic analog of prostaglandin F2-alphaUsed for increased intraocular pressure in patients with open-angle glaucoma or ocular hypertensionAssociated with increased pigmentation of iris, eyelid, and eyelashes Indications Indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or…

  • Bimatoprost

    Brands Classes DEA Class; Rx Common Brand Names; Latisse, Lumigan, Durysta Antiglaucoma, Prostaglandin Agonists Description Synthetic analog of prostaglandin; available as an ophthalmic solution and intracameral implantUsed to lower IOP in patients with open-angle glaucoma or ocular hypertension; also approved for hypotrichosisAssociated with increased pigmentation of eyelashes, iris, and periorbital tissue; changes in iridal pigmentation…

  • Misoprostol

    Brands Classes DEA Class; Rx Common Brand Names; Cytotec Gastrointestinal Agents, Other;  Prostaglandins, Endocrine Description Synthetic, oral prostaglandin E1 (PGE1) analog approved for prevention of gastric ulcers secondary to use of nonsteroidal antiinflammatory drugs (NSAIDs); taken for the duration of NSAID therapyBoxed warning regarding the abortifacient effects and reproductive risk; females of childbearing age must…

  • Lubiprostone

    Brands Classes DEA Class; Rx Common Brand Names; Amitiza IBS Agents;  Laxatives, Other Description Chloride channel (CIC-2) activatorUsed to treat adults with chronic idiopathic constipation or opiate agonist-induced constipation (OIC), and in adult women with constipation-predominant irritable bowel syndrome (IBS-C)Most common side effect is nausea Indications Indicated for the treatment of chronic idiopathic constipation (e.g.,…

  • Alprostadil

    Brands Classes DEA Class; Rx Common Brand Names; Caverject, Edex, Muse, PGE1, Prostaglandin E1, Viridal Prostaglandins, Genitourinary Description Prostaglandin E-1 Used for erectile dysfunction (ED) and to maintain patency of ductus arteriosus in neonates until surgeryErectile dysfunction products include an intraurethral insert (Muse) and intracavernosal injection (Caverject or Edex); other dosage forms under investigationProstin VR Pediatric is…