Tag: Platelet Inhibitors

  • Tirofiban

    Brands Classes DEA Class; Rx Common Brand Names; Aggrastat Antiplatelet Agents, Cardiovascular;  Glycoprotein IIb/IIIa Inhibitors Description Intravenous nonpeptide, platelet glycoprotein IIb/IIIa inhibitorFor rate reduction of thrombotic cardiovascular events in patients with non-ST elevation acute coronary syndromesReversible platelet inhibition within 4—8 hours of discontinuation Indications Indicated to reduce rate of thrombotic cardiovascular events (combined endpoint of…

  • Ticlopidine

    Discontinued Classes DEA Class; Discontinued Common Brand Names; Ticlid Antiplatelet Agents, Cardiovascular;  Antiplatelet Agents, Hematologic Description Oral platelet-aggregation inhibitor; associated with a risk of life-threatening blood dyscrasias; should be reserved for patients who are intolerant or allergic to aspirin therapy or who have failed aspirin therapy. Indications Indicated for arterial thromboembolism prophylaxis (e.g., stroke prophylaxis)…

  • Ticagrelor

    Brands Classes DEA Class; Rx Common Brand Names; Brilinta Antiplatelet Agents, Cardiovascular Description Oral platelet P2Y12 ADP receptor antagonistUsed to reduce thrombotic cardiovascular events in patients with acute coronary syndrome (ACS) and patients with coronary artery disease without history of stroke or myocardial infarction; to reduce the risk of stroke in patients with acute ischemic…

  • Prasugrel

    Brands Classes DEA Class; Rx Common Brand Names; Effient Antiplatelet Agents, Cardiovascular;  Antiplatelet Agents, Hematologic Description Thienopyridine platelet aggregation inhibitorUsed to reduce thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndromes (ACS) being managed with percutaneous coronary intervention (PCI)Reduced cardiovascular death, predominantly due to a reduction in the incidence of myocardial infarction…

  • Eptifibatide

    Brands Classes DEA Class; Rx Common Brand Names; Integrilin Antiplatelet Agents, Cardiovascular;  Glycoprotein IIb/IIIa Inhibitors Description Intravenous platelet aggregation, glycoprotein IIb/IIIa inhibitorUsed for the treatment of patients undergoing percutaneous coronary intervention (PCI) and acute coronary syndromes managed medically or with PCIAssociated with bleeding and hypotension Indications Indicated for the adjunctive treatment of patients undergoing percutaneous…

  • Dipyridamole

    Brands Classes DEA Class; Rx Common Brand Names; Persantine Antiplatelet Agents, Cardiovascular;  Antiplatelet Agents, Hematologic Description Oral, P2Y12 platelet inhibitorUsed for rate reduction of myocardial infarction (MI) and stroke in patients with non-ST-elevation acute coronary syndromes, STEMI, established peripheral arterial disease, or recent MI or strokeAssociated with diminished antiplatelet effect in CYP2C19 poor metabolizers Indications…

  • Clopidogrel

    Brands Classes DEA Class; Rx Common Brand Names; Plavix Antiplatelet Agents, Cardiovascular;  Antiplatelet Agents, Hematologic Description Oral, P2Y12 platelet inhibitorUsed for rate reduction of myocardial infarction (MI) and stroke in patients with non-ST-elevation acute coronary syndromes, STEMI, established peripheral arterial disease, or recent MI or strokeAssociated with diminished antiplatelet effect in CYP2C19 poor metabolizers Indications…

  • Cilostazol

    Brands Classes DEA Class; Rx Common Brand Names; Pletal Antiplatelet Agents, Hematologic;  PDE-3 Inhibitors;  Phospholipase A2 Inhibitors Description Platelet aggregation inhibitor with vasodilating activity; for the reduction of the symptoms of intermittent claudication. Indications Indicated for the treatment of claudication associated with peripheral vascular disease (PVD); including the treatment of peripheral arterial disease in patients…

  • Cangrelor

    Brands Classes DEA Class; Rx Common Brand Names; Kengreal Antiplatelet Agents, Cardiovascular Description Injectable P2Y12 platelet inhibitor indicated as an adjunct to PCI in patients not already receiving an oral P2Y12 inhibitor or glycoprotein IIb/IIIa inhibitorOnset of platelet inhibitor occurs within 2 minutes of initiation of therapy and returns to normal within 1 hour of…

  • Abciximab

    Brands Classes DEA Class; Rx Common Brand Names; ReoPro Antiplatelet Agents, Cardiovascular;  Glycoprotein IIb/IIIa Inhibitors Description Platelet glycoprotein IIb/IIIa receptor antagonistAdjunctive therapy for preventing cardiac ischemic complications in percutaneous coronary intervention (PCI) or in patients with unresponsive unstable anginaFab fragment of the chimeric monoclonal antibody 7E3 Indications Indicated for the Prevention of cardiac ischemic complications…