Tag: Penicillins
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Amoxicillin/Clavulanic Acid
Brands Classes Amoxicillin/Clavulanate DEA Class; Rx Common Brand Names; Augmentin, Augmentin XR, Augmentin ES-600 Penicillins, Amino Description Contains amoxicillin and clavulanic acid; clavulanic acid is a beta-lactamase inhibitor that reestablishes amoxicillin’s activity against beta-lactamase-producing bacteria; drug combination has good activity against beta-lactamase producing H. influenzae and penicillinase-producing anaerobes; used commonly for upper respiratory infections, otitis media…
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Penicillin V
Brands Classes DEA Class; Rx Common Brand Names; Pen Vee K, Penicillin V, Veetids Penicillins, Natural Description Naturally derived penicillin antibiotic. Preferred over penicillin G when oral administration is desired due to better gastric acid stability, which results in higher plasma levels. Amoxicillin is preferred over pencillin V in some clinical situations such as endocarditis prophylaxis.…
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Penicillin G Benzathine/Penicillin G Procaine
Brands Classes DEA Class; Rx Common Brand Names; Bicillin C-R, Bicillin C-R 900/300 Penicillins, Natural Description Combination of 2 long acting penicillins for intramuscular use only; tissue depot allows slow drug absorption; provides lower and prolonged serum concentrations compared to aqueous penicillin G; used in moderately severe infections due to susceptible streptococci and pneumococci; contraindicated…
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Penicillin G Benzathine
Brands Classes DEA Class; Rx Common Brand Names; Bicillin LA, Permapen Penicillins, Natural Description Repository form of penicillin for intramuscular use only; tissue depot allows slow drug absorption over several days; provides lower and prolonged serum concentrations compared to aqueous penicillin G; used in mild to moderate infections due to susceptible organisms, prophylaxis and treatment…
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Penicillin G Procaine
Brands Classes DEA Class; Rx Common Brand Names; Wycillin Penicillins, Natural Description Equimolar compound of procaine and penicillin G antibiotic for intramuscular use; tissue depot allows slow drug absorption with plateau type blood concentrations over several hours; used in moderately severe infections due to penicillin G susceptible organisms. Indications Indicated for moderately severe uncomplicated pneumococcal…
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Penicillin G Aqueous
Brands Classes DEA Class; Rx Common Brand Names; Pfizerpen, penicillin G potassium, penicillin G sodium, Crystapen Penicillins, Natural Description Naturally derived antibiotic for parenteral use. Commercially available as salts of potassium or sodium; these aqueous and crystalline forms administered IV or IM. Primary agent for Streptococcus pyogenes, S. pneumoniae, and enterococcal infections. Drug of choice for…
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Oxacillin
Brands Classes DEA Class; Rx Common Brand Names; Bactocill Penicillins, Penicillinase-Resistant Description Semisynthetic antistaphylococcal penicillin. Stable against penicillinase. Main use is for treating infections caused penicillinase-producing S. aureus, including bacteremia, skin and soft-tissue infections, respiratory tract infections, bone and joint infections, and UTIs. Indications Indicated for the treatment of bacteremia due to methicillin-sensitive S. aureus.…
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Nafcillin
Brands Classes DEA Class; Rx Common Brand Names; Nafcil, Nallpen Penicillins, Penicillinase-Resistant Description Oral semisynthetic isoxazolyl antistaphylococcal penicillin. Most active of the isoxazolyl antistaphylococcal penicillins. Stable against penicillinase and active against many of the penicillinase-producing strains of Staphylococcus aureus. Clinical uses include skin and soft-tissue, bone and joint, respiratory tract, and urinary tract infections. Indications…
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Dicloxacillin
Generic Only Classes DEA Class; Rx Common Brand Names; Dynapen Penicillins, Penicillinase-Resistant Description Oral semisynthetic isoxazolyl antistaphylococcal penicillin. Most active of the isoxazolyl antistaphylococcal penicillins. Stable against penicillinase and active against many of the penicillinase-producing strains of Staphylococcus aureus. Clinical uses include skin and soft-tissue, bone and joint, respiratory tract, and urinary tract infections. Indications…
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Ampicillin/Sulbactam
Brands Classes DEA Class; Rx Common Brand Names; Unasyn Penicillins, Amino Description Parenteral antibiotic combining ampicillin with sulbactam (a beta-lactamase inhibitor); sulbactam enhances ampicillin’s spectrum to include many beta-lactamase-producing bacteria; similar coverage to oral amoxicillin-clavulanic acid combination; main uses of ampicillin-sulbactam: intra-abdominal infections, gynecologic infections, and skin and soft-tissue infection; not indicated for meningitis. Indications…
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Ampicillin
Brands Classes DEA Class; Rx Common Brand Names; Ampi, Omnipen, Penglobe, Principen Penicillins, Amino Description Aminopenicillin similar to amoxicillin; not stable to beta-lactamases of either gram-positive or gram-negative bacteria; used commonly for obstetric infections, otitis media, sinusitis and other infections due to susceptible organisms; oral ampicillin exhibits lower bioavailability and higher incidence of GI effects than…
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Amoxicillin/Clavulanate
Brands Classes Amoxicillin/Clavulanic Acid DEA Class; Rx Common Brand Names; Augmentin, Augmentin XR, Augmentin ES-600 Penicillins, Amino Description Contains amoxicillin and clavulanic acid; clavulanic acid is a beta-lactamase inhibitor that reestablishes amoxicillin’s activity against beta-lactamase-producing bacteria; drug combination has good activity against beta-lactamase producing H. influenzae and penicillinase-producing anaerobes; used commonly for upper respiratory infections, otitis…
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Vonoprazan/Amoxicillin/Clarithromycin
Brands Classes DEA Class; Rx Common Brand Names; Voquezna Triple Pak H pylori Agents; Potassium-Competitive Acid Blockers Description Vonoprazan Potassium-competitive acid blocker (PCAB) Suppresses basal and stimulated gastric acid secretion at secretory surface of gastric parietal cell through inhibition of the H+, K+-ATPase enzyme system in a potassium-competitive manner Because this enzyme is regarded as…
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Vonoprazan/Amoxicillin
Brands Classes DEA Class; Rx Common Brand Names; Voquezna Dual Pak Potassium-Competitive Acid Blockers; H pylori Agents Description Vonoprazan Potassium-competitive acid blocker (PCAB) Suppresses basal and stimulated gastric acid secretion at secretory surface of gastric parietal cell through inhibition of the H+,K+-ATPase enzyme system in a potassium-competitive manner Because this enzyme is regarded as the…
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Amoxicillin/Omeprazole/Rifabutin
Brands Classes DEA Class; Rx Common Brand Names; Talicia H pylori Agents; PUD Combos Description Rifabutin: Elicits antibacterial effects by inhibiting DNA-dependent RNA polymerase Omeprazole: Proton pump inhibitor; binds to H+/K+-exchange ATPase (proton pump) in gastric parietal cells resulting in blocking acid secretion Amoxicillin: Ampicillin derivative; elicits antibacterial effect by inhibiting biosynthesis of cell wall…