Tag: Oral Agents

Brands Classes DEA Class; Rx Common Brand Names; Synjardy, Synjardy XR Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitusContraindicated in severe renal impairment Indications Indicated for the treatment of type 2 diabetes mellitus in combination with diet and exercise…

Brands Classes DEA Class; Rx Common Brand Names; Glyxambi Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of a sodium-glucose co-transporter 2 (SGLT2) inhibitor combined with a dipeptidyl peptidase-4 (DPP-4) inhibitorUsed for adults with type 2 diabetes mellitus not adequately controlled on either drug alone; when used with metformin, many patients achieve target…

Brands Classes DEA Class; Rx Common Brand Names; Jardiance Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitus (DM); to reduce the risk of cardiovascular (CV) death in adults with type 2 DM and established CV disease; to reduce risk of CV death and heart failure (HF)…

Brands Classes DEA Class; Rx Common Brand Names; Qternmet XR Antidiabetics, Biguanides;  Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of a sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitorUsed for adults with type 2 diabetes mellitus; when used with metformin, patients may achieve A1C targetsContraindicated for patients with eGFR less…

Brands Classes DEA Class; Rx Common Brand Names; Qtern Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of a sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitorUsed for adults with type 2 diabetes mellitus; when used with metformin, patients may achieve A1C targetsContraindicated for patients with eGFR less than 45 mL/minute/1.73…

Brands Classes DEA Class; Rx Common Brand Names; Xigduo XR Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitus; to reduce the risk of hospitalization for heart failure in adults with T2DM and established CV disease or multiple CV risk…

Brands Classes DEA Class; Rx Common Brand Names; Farxiga Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed for improving glycemic control in adults with type 2 diabetes mellitus (DM); reducing hospitalization for heart failure (HF) in adults with type 2 DM and established cardiovascular (CV) disease or multiple CV risk factors; reducing CV…

Brands Classes DEA Class; Rx Common Brand Names; Invokamet, Invokamet-XR Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed for adults with type 2 diabetes mellitusContraindicated in severe renal impairment due to reduced canagliflozin efficacy and increased risk of metformin-related lactic acidosis Indications Indicated for the treatment…

Brands Classes DEA Class; Rx Common Brand Names; Invokana Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitus; also provides cardiovascular (CV) risk reduction if CV disease also present; if diabetic nephropathy with albuminuria is present, the drug reduces the risk of end-stage kidney disease, doubling of…

Brands Classes DEA Class; Rx Common Brand Names; Nesina Antidiabetics, Dipeptyl Peptidase-IV Inhibitors Description Oral DPP-4 inhibitor given once daily; reduces breakdown of GLP-1 which increases insulin secretionUsed for type 2 diabetes mellitus in adults; mean A1C reduction 0.4 to 0.6%Used as monotherapy or in combination with other hypoglycemic agents including insulin, but not GLP-1…

Brands Classes DEA Class; Rx Common Brand Names; Precose Antidiabetics, Alpha-Glucosidase Inhibitors Description Oral alpha-glucosidase inhibitor; minimal systemic absorptionUsed for the treatment of type 2 diabetes mellitusAgents in this class have only modest effects on A1C (i.e., mean 0.3% to 0.7% reduction) Indications Indicated for the treatment of type 2 diabetes mellitus as an adjunct…