Tag: Oral Agents

Brands Classes DEA Class; Rx Common Brand Names; Kazano Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors Description Oral combination of a biguanide (metformin) and a dipeptidy-peptidase-4 (DPP-4) inhibitor (alogliptin)Used in adults for the treatment of type 2 diabetes mellitusPer boxed warning the risk of lactic acidosis due to metformin requires care in prescribing and monitoring Indications Indicated as…

Brands Classes DEA Class; Rx Common Brand Names; Glucophage, Glucophage XR, Glumetza, Riomet, Riomet ER Antidiabetics, Biguanides Description Oral biguanide antidiabetic agentUsed for type 2 diabetes mellitus (T2DM) in adult and pediatric patients 10 years and older; first-line T2DM therapy generally includes metforminRisk of lactic acidosis is low but requires care in prescribing and monitoring Indications…

Brands Classes DEA Class; Rx Common Brand Names; Jentadueto, Jentadueto XR Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors Description Oral combination of a biguanide (metformin) and a dipeptidy-peptidase-4 (DPP-4) inhibitor (linagliptin)Used in adults for the treatment of type 2 diabetes mellitusPer boxed warning the risk of lactic acidosis due to metformin requires care in prescribing and monitoring Indications…

Brands Classes DEA Class; Rx Common Brand Names; Tradjenta Antidiabetics, Dipeptyl Peptidase-IV Inhibitors Description Oral DPP-4 inhibitor given once daily; reduces breakdown of GLP-1 which increases insulin secretionUsed in adults with type 2 diabetes mellitus; mean A1C reduction 0.7%Used as monotherapy or in combination with other medications, with the exception of GLP-1 agonists Indications Indicated…

Brands Classes DEA Class; Rx Common Brand Names; Glucovance Antidiabetics, Sulfonylureas/Biguanides Description Oral combination of metformin with a ‘second-generation’ sulfonylureaUsed in adults for type 2 diabetes mellitus; due to longer duration of action, glyburide is not preferred in the elderlyRisk of lactic acidosis from metformin is low but requires care in monitoring Indications Indicated for…

Brands Classes DEA Class; Rx Common Brand Names; Diabeta, Glynase, Glynase PresTab Antidiabetics, Sulfonylureas Description Second-generation sulfonylurea; twice as potent as glipizide and longer duration of actionUsed primarily in adults for the treatment of type 2 diabetes mellitusDue to longer duration of action, not a preferred sulfonylurea in the elderly Indications Indicated for the treatment of…

Brands Classes DEA Class; Rx Common Brand Names; Metaglip Antidiabetics, Sulfonylureas/Biguanides Description Oral combination of metformin with a ‘second-generation’ sulfonylureaUsed in adults for type 2 diabetes mellitus; glipizide preferred over glyburide for the elderly due to no active metabolitesRisk of lactic acidosis from metformin is low but requires care in monitoring Indications Indicated for the…

Brands Classes DEA Class; Rx Common Brand Names; Glucotrol, Glucotrol XL, Minodiab Antidiabetics, Sulfonylureas Description Second-generation sulfonylurea; shorter duration of action than glyburide; no active metabolitesUsed primarily in adults for the treatment of type 2 diabetes mellitus, as add-on therapy to metformin or other agentsGlipizide is preferred over glyburide for use in the elderly and in…

Brands Classes DEA Class; Rx Common Brand Names; Duetact Antidiabetics, Sulfonylureas/Thiazolidinediones Description Combination of pioglitazone, a thiazolidinedione, and glimepiride, a second-generation sulfonylureaUsed in adults for the treatment of type 2 diabetes mellitusMonitor patients for hypoglycemia, edema, weight gain, and heart failure Indications Indicated for management of type 2 diabetes mellitus as adjunct to diet and…

Brands Classes DEA Class; Rx Common Brand Names; Avandaryl Antidiabetics, Sulfonylureas/Thiazolidinediones Description Combination of glimepiride, a sulfonylurea, and rosiglitazone, a thiazolidinedione.Used for treatment of type 2 diabetes mellitus; combination may increase risk of hypoglycemia vs monotherapy. Indications Indicated for the treatment of type 2 diabetes mellitus uncontrolled by diet and exercise alone.NOTE: Patients treated with…

Brands Classes DEA Class; Rx Common Brand Names; Amaryl Antidiabetics, Sulfonylureas Description Second-generation sulfonylurea; weakly active metabolitesUsed primarily in adults for the treatment of type 2 diabetes mellitus, as add-on therapy to metformin or other agentsGlipizide is preferred over glyburide for use in the elderly and in patients with renal dysfunction, but glimepiride can also…

Brands Classes DEA Class; Rx Common Brand Names; Steglujan Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitor combination productUsed for adults with type 2 diabetes mellitus; when used with metformin, many patients achieve A1C targetsContraindicated in severe renal impairment, as ertugliflozin efficacy is reduced…

Brands Classes DEA Class; Rx Common Brand Names; Segluromet Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitusContraindicated in severe renal impairment due to reduced ertugliflozin efficacy and increased risk of metformin-related lactic acidosis Indications Indicated as adjunct to diet…

Brands Classes DEA Class; Rx Common Brand Names; Steglatro Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed for adults with type 2 diabetes mellitusNot recommended for patients with an eGFR less than 45 mL/minute/1.73 m2 as efficacy is reduced and renal-related adverse reactions may increase Indications Indicated as an adjunct to diet and…

Brands Classes DEA Class; Rx Common Brand Names; Trijardy XR Antidiabetics, Biguanides;  Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Empagliflozin: SGLT2 inhibitor; SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen; SGLT2 inhibitors reduce glucose reabsorption and lower the…