Tag: Monoclonal Antibodies

Brands Classes DEA Class; Rx Common Brand Names; Herceptin Hylecta, trastuzumab-hyaluronidase-oysk Antineoplastics, Anti-HER2;  Antineoplastics, Monoclonal Antibody   Description Trastuzumab is a HER2/neu receptor antagonist; hyaluronidase is an endoglycosidaseUsed for the treatment of HER2-overexpressing breast cancerDo not substitute trastuzumab; hyaluronidase with other trastuzumab-based products; both administration and dosing recommendations are different Indications Indicated for adjuvant treatment…

Brands Classes DEA Class; Rx Common Brand Names; Herceptin, Ogivri, Herzuma, Ontruzant, Trazimera, Kanjinti, trastuzumab-dkst, trastuzumab-pkrb, trastuzumab-dttb, trastuzumab-qyyp, trastuzumab-anns  Antineoplastics, Anti-HER2;  Antineoplastics, Monoclonal Antibody Description Recombinant DNA-derived humanized IgG1 kappa monoclonal antibody against the HER2 proteinUsed for breast and gastric cancers that overexpress HER2Monitor left ventricular ejection fraction in all patients before, during, and after treatment;…

Brands Classes DEA Class; Rx Common Brand Names; Rituxan, Truxima, rituximab-abbs, Ruxience, rituximab-pvvr, rituximab-arrx, Riabni DMARDs, Other;  Antineoplastics, Anti-CD20 Monoclonal Antibodies Description Anti-CD20 monoclonal antibodyUsed for non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgarisBoxed warnings for severe infusion-related and mucocutaneous reactions, risk of hepatitis B virus reactivation, and progressive…

Brands Classes DEA Class; Rx Common Brand Names; Cyramza Antineoplastics, VEGF Inhibitor Description Intravenous human monoclonal antibody that inhibits VEGFR2Used for advanced gastric or gastro-esophageal junction adenocarcinoma, metastatic NSCLC, and hepatocellular cancerSevere infusion reactions have occurred; premedicate all patients with IV diphenhydramine or equivalent; add acetaminophen and dexamethasone (or equivalent) for patients with a previous…

Brands Classes DEA Class; Rx Common Brand Names; Vectibix Antineoplastics, Monoclonal Antibody;  Antineoplastics, EGFR Inhibitor Description Anti-EGFR monoclonal antibodyUsed for wild-type RAS metastatic colorectal cancer as monotherapy or in combination with chemotherapyDermatologic adverse reactions and severe infusion reactions may occur Indications Indicated for both KRAS and NRAS as determined by an FDA-approved test for this…

Brands Classes DEA Class; Rx Common Brand Names; Darzalex Antineoplastics, Monoclonal Antibody;  Antineoplastics, Anti-CD38 Monoclonal Antibodies Description Anti-CD38 monoclonal antibodyUsed as monotherapy or in combination with other agents for multiple myelomaType and cross-match patient blood prior to starting treatment Indications Multiple Myeloma Newly diagnosed multiple myeloma Combination therapy with bortezomib, melphalan, and prednisone Indicated in…

Brands Classes DEA Class; Rx Common Brand Names; Erbitux Antineoplastics, Monoclonal Antibody;  Antineoplastics, EGFR Inhibitor Description Anti-EGFR monoclonal antibodyUsed for EGFR-positive, Ras wild-type, metastatic colorectal cancer (mCRC); BRAF V600E-mutated mCRC; and locally advanced or metastatic head and neck cancerCan cause serious infusion reactions and cardiopulmonary arrest; dermatologic toxicities are common Indications Indicated for KRAS mutation-negative…

Brands Classes DEA Class; Rx Common Brand Names; Avastin, Mvasi, bevacizumab-awwb, Zirabev, bevacizumab-bvzr, Alymsys, bevacizumab-maly, bevacizumab-adcd, Vegzelma Antineoplastics, Monoclonal Antibody;  Antineoplastics, VEGF Inhibitor Description Humanized monoclonal antibody against vascular endothelial growth factorUsed for metastatic colorectal cancer, hepatocellular cancer, renal cell cancer, non-small cell lung cancer, cervical cancer, recurrent glioblastoma, and epithelial ovarian, fallopian tube, or primary…