Tag: Leukotriene Modifiers

Brands Classes DEA Class; Rx Common Brand Names; Zyflo Filmtab, Zyflo, Zyflo CR 5-Lipoxygenase Inhibitors Description Oral 5-lipoxygenase inhibitor; limits leukotriene productionUsed for add-on asthma maintenance therapy in adult and pediatric patients 12 years and older; off-label use for exercise-induced bronchospasm (EIB) in adultsDue to a potential for hepatotoxicity, periodic monitoring of liver function tests is…

Brands Classes DEA Class; Rx Common Brand Names; Accolate  Leukotriene Receptor Antagonists Description Leukotriene receptor antagonist (LTRA)Used for add-on asthma maintenance therapy in adult and pediatric patients 5 years and older; off-label use for allergic rhinitis and exercise-induced bronchospasmInhibits some CYP hepatic enzymes, which may lead to drug interactions; associated with rare hepatic toxicity Indications…

Brands Classes DEA Class; Rx Common Brand Names; Singulair Leukotriene Receptor Antagonists Description Oral leukotriene receptor antagonist (LRTA) class anti-inflammatory agentUsed for mild persistent asthma (age 1 year and older); seasonal allergic rhinitis (2 years and older), perennial allergic rhinitis (6 months and older); and exercise-induced bronchoconstriction (EIB) prophylaxis (6 years and older)Boxed warning for…