Tag: Inhibitors of Folate Synthesis (Antibiobics)

  • Sulfasalazine

    Brands Classes DEA Class; Rx Common Brand Names; Azulfidine, Azulfidine EN 5-Aminosalicylic Acid Derivatives;  DMARDs, Other Description Oral prodrug; metabolized by intestinal bacteria to sulfapyridine and 5-aminosalicylate (5-ASA, also known as mesalamine)Used to treat ulcerative colitis, rheumatoid arthritis, and juvenille idiopathic arthritis (JIA)The sulfapyridine component is particularly associated with adverse reactions vs. 5-ASA use alone…

  • Sulfadiazine

    Generic Only Classes DEA Class; Rx Common Brand Names;  Sulfonamides Description Exerts bacteriostatic action through competitive antagonism with para-aminobenzoic acid (PABA). Microorganisms that require exogenous folic acid and do not synthesize folic acid are not susceptible to the action of sulfonamides Indications Indicated for Prophylaxis of Recurrent Rheumatic Fever Asymptomatic meningococcal  Other Indications & Uses…

  • Silver Sulfadiazine

    Brands Classes DEA Class; Rx Common Brand Names; Silvadene, Thermazene, SSD Cream Antibacterials, Topical Description Topical sulfonamide antiinfective; wide spectrum of activity against Candida and gram-positive and gram-negative bacteria; used to prevent and treat serious burn and wound infections. Indications Indicated for wound management including the treatment of burn wound infection and burn wound infection prophylaxis…

  • Mafenide

    Brands Classes DEA Class; Rx Common Brand Names; Sulfamylon Antibacterials, Topical Description Synthetic topical sulfonamide.Used adjunctively to prevent infections in patients with 2nd- and 3rd-degree burns.Bacteriostatic against many gram-positive and gram-negative bacteria, including Pseudomonas aeruginosa and several anaerobic strains. Indications Indicated for wound management including the treatment of second or third degree burns or burn…