DrugsAce

Tag: Immunosuppressants

  • Desloratadine

    Brands Classes DEA Class; OTC, Rx Common Brand Names; Clarinex, Clarinex RediTabs Antihistamines, 2nd Generation Description Oral non-sedating, long acting second-generation antihistamine; the active metabolite of loratadineUsed to relieve symptoms associated with seasonal and perennial allergic rhinitis and used for chronic idiopathic urticariaDoes not cause QT prolongation Indications Indicated for the management of symptoms of…

  • Brompheniramine/Dextromethorphan/Phenylephrine

    Brands Classes DEA Class; OTC Common Brand Names; Neo DM Suspension, Dimaphen DM, Children’s Dimetapp Cold & Cough Cough/Cold, Non-narcotic Combos;  Antihistamine/Antitussive/Decongestant Combos Description Oral sedating antihistamine and non-opioid antitussive combinationUsed to relieve symptoms associated with the common cold or allergies including rhinorrhea, sneezing, and cough in adults and pediatric patients 6 years and olderThese products…

  • Mycophenolate

    Brands Classes DEA Class; Rx Common Brand Names; CellCept, Myfortic, MMF Immunosuppressants   Description Immunosuppressant with mycophenolic acid (MPA) as active component; similar efficacy with mofetil or sodium formulasUsed for organ rejection prophylaxis in conjunction with other immunosuppressants, in adult and pediatric patients 3 months and olderMay increase the risk of fetal harm (birth defects) and…

  • Sirolimus

    Brands Classes DEA Class; Rx Common Brand Names; Rapamune Immunosuppressants sirolimus topical (Rx) Brand and Other Names: Hyftor Classes: Dermatologics, mTOR Inhibitors sirolimus protein bound (Rx) Brand and Other Names: Fyarro Classes: Antineoplastics, mTOr Kinase Inhibitor   Description Immunosuppressant; analog of tacrolimusOral formulations for prophylaxis of organ rejection in renal transplant patients and for lymphangioleiomyomatosis; topical gel for facial…

  • Everolimus

    Brands Classes DEA Class; Rx Common Brand Names; Afinitor, Zortress, Afinitor Disperz Antineoplastics, mTOr Kinase Inhibitors Description Macrolide immunosuppressant analog of sirolimus; inhibits the mammalian target of rapamycin (mTOR), a serine-threonine kinaseAfinitor is used for certain patients with breast cancer, neuroendocrine tumors of pancreatic, GI, or lung origin, renal cell carcinoma, and certain tuberous sclerosis complex…

  • Belatacept

    Brands Classes DEA Class; Rx Common Brand Names; Nulojix Immunosuppressants;  Selective T-Cell Costimulation Blockers Description Selective T-cell costimulation blockerFor rejection prophylaxis in adults receiving a kidney transplantMay increase risk for developing post-transplant lymphoproliferative disorder; ONLY use in Epstein-Barr virus seropositive patients Indications Indicated for use in combination with basiliximab induction, mycophenolate mofetil, and corticosteroids to…

  • Tacrolimus

    Brands Classes DEA Class; Rx Common Brand Names; Prograf, Astagraf XL, Hecoria, Envarsus XR, Protopic Immunosuppressants;  Calcineurin Inhibitors Description Immunosuppressant; more potent than cyclosporine Used for graft rejection prophylaxis and treatment of acute or refractory graft rejection; considered an alternative to cyclosporine; topical formulation used for atopic dermatitisIncreased susceptibility to infections and secondary malignancy possible Indications Indicated…

  • Cyclosporine

    Brands Classes DEA Class; Rx Common Brand Names; Neoral, Sandimmune, Gengraf DMARDs, Immunomodulators;  Immunosuppressants;  Calcineurin Inhibitors   Description Immunosuppressive; cyclic polypeptide consisting of 11 amino acidsUsed to prevent organ rejection and in various autoimmune conditions; ophthalmic 0.05% emulsion and 0.09% solution used to increase tear production in patients with ocular inflammation associated with keratoconjunctivitis; 0.1% ophthalmic…

  • Basiliximab

    Brands Classes DEA Class; Rx Common Brand Names; Simulect Immunouppressants;  Monoclonal Antibodies Description Immunosuppressant; chimeric (murine/human) monoclonal antibody (IgG); binds to and blocks the interleukin-2 receptor alpha chain (CD25); has not been associated with an increased risk of lymphoma or other malignancies. Indications Indicated for acute kidney transplant rejection prophylaxis when used as part of…

  • Antithymocyte Globulin

    Brands Classes DEA Class; Rx Common Brand Names; Atgam, ATG equine Immunosuppressants;  Polyclonal Antibodies Description Immunosuppressant, polyclonal IgG against human T-lymphocytes derived from horses (Atgam) or rabbits (Thymoglobulin)Used for kidney organ transplant rejection, organ transplant rejection prophylaxis, and moderate to severe aplastic anemiaRisk of serious hypersensitivity reactions, including anaphylaxis or cytokine release syndrome (CRS) Indications…