Tag: Hormones and Drugs Affecting the Hypothalamus and pituitary

  • Urofollitropin

    Brands Classes DEA Class; Rx Common Brand Names; Bravelle, Fertinorm HP Gonadotropins;  Ovulation Stimulators Description Human-derived urinary gonadotropin; lower cost than recombinant FSH; primarily contains FSH with negligible (< 0.1 IU) LH activity per 1000 IU of FSH activity; used for infertility protocols for ovulation induction; also used for spermatogenesis induction in men with reproductive failure due…

  • Somatropin

    Brands Classes DEA Class; Rx Common Brand Names; Genotropin, Genotropin Miniquick, Genotropin Pen 12, Humatrope, Norditropin FlexPro, Nutropin, Nutropin AQ NuSpin 20, Nutropin AQ NuSpin 10, Nutropin AQ NuSpin 5, Omnitrope, Saizen, Serostim, Zorbtive, Nutropin AQ Pen 20, Nutropin AQ Pen 10, Zomacton Growth Hormone Analogs Description Recombinant growth hormone; less immunogenic than somatremUsed for growth…

  • Octreotide

    Brands Classes DEA Class; Rx Common Brand Names; Sandostatin, Sandostatin LAR, Bynfezia Pen, Mycapssa Antidiarrheals;  Somatostatin Analogs Description Synthetic analog of somatostatinInjections used for acromegaly, vasoactive intestinal peptide tumors (VIPomas; watery diarrhea), metastatic carcinoid tumors, AIDS-associated diarrhea, esophageal varices, and other indications; oral formula used for acromegaly in adultsGastrointestinal adverse effects are common; cholelithiasis may be…

  • Nafarelin

    Brands Classes DEA Class; Rx Common Brand Names; Synarel Gonadotropin Releasing Hormone Agonists Description Intranasal synthetic analog of GnRH used for treatment of central precocious puberty in children and for endometriosis, uterine fibroids, and hirsutism in women. Maximum recommended length of therapy in women is 6 months due to risk of osteoporosis. Also used for…

  • Menotropins

    Brands Classes DEA Class; Rx Common Brand Names; Menopur, Repronex Gonadotropins;  Ovulation Stimulators Description Purified preparation of FSH and LH, obtained from the urine of postmenopausal women; also referred to as HMG; used for ovulation induction and associated with multiparity; also used for oligospermia in males in combination with hCG; highly purified products are of…

  • Leuprolide

    Brands Classes DEA Class; Rx Common Brand Names; Lupron, Lupron Depot, Lupron Depot 3 Month, Lupron Depot 4 Month, Lupron Depot 6 Month, Lupron Depot-Ped, Eligard, Fensolvi, Camcevi Antineoplastics, GNRH Agonist Description Synthetic nonpeptide analog of gonadotropin-releasing hormone (GnRH)Used for endometriosis, precocious puberty, prostate cancer, and uterine fibroidsMay cause an increase in symptoms during the first…

  • Lanreotide

    Brands Classes DEA Class; Rx Common Brand Names; Somatuline Depot Somatostatin Analogs Description Subcutaneous, long-acting analog of somatostatin given as depot injectionUsed for the treatment of acromegaly, gastroenteropancreaticneuroendocrine tumors (GEP-NETs), and carcinoid syndromeMay decrease gallbladder motility and lead to gallstone formation; may also affect blood glucose and thyroid function tests, and may cause bradycardia Indications…

  • Histrelin

    Brands Classes DEA Class; Rx Common Brand Names; Supprelin LA, Vantas Antineoplastics, GNRH Agonist Description A gonadotropin-releasing hormone (GnRH) agonistUsed for the palliative treatment of advanced prostate cancer or the treatment of central precocious puberty in childrenInitial increases in hormone levels may cause temporary worsening of symptoms; implant insertion is a surgical procedure Indications Indicated…

  • Goserelin

    Brands Classes DEA Class; Rx Common Brand Names; Zoladex, Zoladex LA Antineoplastics, GNRH Agonist Description A synthetic gonadotropin-releasing hormone (GnRH) agonistUsed for the palliative treatment of advanced prostate cancer or breast cancer, for the management of endometriosis, dysfunctional uterine bleeding, and the adjunct medical management of uterine fibroidsA transient tumor flare may occur during the…

  • Follitropin Beta

    Brands Classes DEA Class; Rx Common Brand Names; Follistim AQ Gonadotropins;  Ovulation Stimulators Description Products ar recombinant versions of human follicle stimulating hormone (FSH), a gonadotropin; available as follitropin alfa or follitropin betaUsed for infertility protocols for ovulation induction in selected females and for induction of spermatogenesis in selected malesUsed in combination with human chorionic…

  • Follitropin Alfa

    Brands Classes DEA Class; Rx Common Brand Names; Gonal-f, Gonal-f RFF Gonadotropins;  Ovulation Stimulators Description Products ar recombinant versions of human follicle stimulating hormone (FSH), a gonadotropin; available as follitropin alfa or follitropin betaUsed for infertility protocols for ovulation induction in selected females and for induction of spermatogenesis in selected malesUsed in combination with human…

  • Cosyntropin

    Brands Classes DEA Class; Rx Common Brand Names; Cortrosyn, Synthetic ACTH Diagnostics, Endocrine Description Parenteral synthetic peptide of corticotropin (ACTH)Used for diagnostic testing of adrenal functionLess potent and less allergenic than other exogenous ACTH preparations Indications Indicated for adrenocortical insufficiency diagnosis. Contraindications Hypersensitivity to cosyntropin, synthetic ACTH, or to any excipients Adverse Effects Flushing Mild…

  • Corticotropin

    Brands Classes DEA Class; Rx Common Brand Names; H.P. Acthar Gel, Purified Cortrophin Gel Corticosteroids Description Parenteral adrenocorticotropic hormone (ACTH); highly purified and extracted from porcine pituitary glandsRepository injection primarily used in adults for multiple sclerosis; other corticosteroids usually preferred for other indicationsIn pediatric patients, repository injection primarily used for infantile spasms in infants and…