Tag: HMG CoA Reductase Inhibitors (Statins)

Brands Classes DEA Class; Rx Common Brand Names; Vytorin Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description Oral antilipemic combination of a potent cholesterol absorption inhibitor (ezetimibe) and HMG-CoA reductase inhibitor (simvastatin); results in synergistic cholesterol-lowering effects; 10—80 mg of simvastatin with ezetimibe achieves LDL reductions of approximately > 51%Used for primary hypercholesterolemia or mixed hyperlipidemia;…

Brands Classes DEA Class; Rx Common Brand Names; Zocor, FloLipid Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description Oral HMG Co-A reductase inhibitor; used for hypercholesterolemia or hypertriglyceridemia; reduces LDL, total cholesterol, TG, and apolipoprotein B; increases HDL; improves mortality in patients with CAD; more potent than fluvastatin or pravastatin; FDA-approved for stroke prophylaxis and homozygous…

Brands Classes DEA Class; Rx Common Brand Names; Roszet Lipid-Lowering Agents, 2-Azetidinones;  Lipid-Lowering Agents, Statins Description Rosuvastatin HMG-CoA reductase inhibitor; inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase Ezetimibe Blocks GI cholesterol absorption via NPC1L1 (Niemann-Pick C1-Like 1) inhibition, reducing cholesterol deliver to the liver This action reduces hepatic cholesterol stores…

Brands Classes DEA Class; Rx Common Brand Names; Crestor, Ezallor Sprinkle Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description Most potent, oral HMG-CoA reductase inhibitorApproved for primary hypercholesterolemia, hyperlipoproteinemia and/or hypertriglyceridemia, heterozygous familial hypercholesterolemia (for patients 8 to 17 years), homozygous familial hypercholesterolemia (for patients 7 years and older), and primary prevention of cardiovascular diseaseLimited metabolism;…

Brands Classes DEA Class; Rx Common Brand Names; Pravachol Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description Oral HMG Co-A reductase inhibitor (statin)Used for hypercholesterolemia, hyperlipoproteinemia, hypertriglyceridemia, primary or secondary prevention of coronary heart disease, and for stroke prophylaxis in adults; used for heterozygous familial hypercholesterolemia in adult and pediatric patients 8 years and olderHepatotoxicity, myopathy,…

Brands Classes DEA Class; Rx Common Brand Names; Livalo, Zypitamag Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description HMG-CoA reductase inhibitor, inhibits rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase Indications To reduce elevated total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG), and to increase high-density lipoprotein cholesterol (HDL-C)…

Brands Classes DEA Class; Rx Common Brand Names; Mevacor, Altoprev Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description Oral antilipemic agent; HMG-CoA reductase inhibitor; used for hypercholesterolemia.   Indications Indicated For the treatment of hypercholesterolemia, including hyperlipidemia, hyperlipoproteinemia, or hypertriglyceridemia, as an adjunct to dietary control. For myocardial infarction prophylaxis (primary prevention).For myocardial infarction prophylaxis (primary…

Brands Classes DEA Class; Rx Common Brand Names; Lescol, Lescol XL Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description Least potent, oral, HMG Co-A reductase inhibitor; used 1-2 times daily to treat hypercholesterolemia; indicated to reduce LDL and total cholesterol, plasma triglycerides, and apolipoprotein B; documented to slow the progression of coronary atherosclerosis in patients with…

Brands Classes DEA Class; Rx Common Brand Names; Lipitor Lipid-Lowering Agents, Statins;  HMG-CoA Reductase Inhibitors Description Potent HMG-CoA reductase inhibitor Used to treat hypercholesterolemia and hypertriglyceridemia, to prevent cardiovascular events in patients at risk for CHD or with clinical evidence of CHD, and for homozygous familial hypercholesterolemia; reduces LDL cholesterol, apoprotein B, and triglycerides; increases HDLHas…