Tag: For Herpesvirus and Cytomegalovirus Infections
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Valganciclovir
Brands Classes DEA Class; Rx Common Brand Names; Valcyte Antivirals, CMV; Antivirals, Other Description Oral antiviral agent; prodrug of acyclovirUsed to treat chickenpox, herpes zoster, herpes labialis (cold sores), and genital herpesFormulated to improve oral bioavailability with less frequent dosing than oral acyclovir Indications Indicated for treatment of CMV retinitis in patients with AIDS Indicated…
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Valacyclovir
Brands Classes DEA Class; Rx Common Brand Names; Valtrex Antivirals, Other Description Oral antiviral agent; prodrug of acyclovirUsed to treat chickenpox, herpes zoster, herpes labialis (cold sores), and genital herpesFormulated to improve oral bioavailability with less frequent dosing than oral acyclovir Indications Indicated for the treatment of Herpes Labialis Herpes Zoster Genital Herpes Contraindications Hypersensitivity…
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Trifluridine
Brands Classes DEA Class; Rx Common Brand Names; Viroptic (DSC) Antivirals, Ophthalmic Description Ophthalmic antiviral preparation with activity against herpes simplex virus (HSV) types 1 and 2, vaccinia virus, and some adenovirus strains; used for primary keratoconjunctivitis and recurrent epithelial keratitis due HSV types 1 and 2; used for epithelial keratitis that has not responded…
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Penciclovir
Brands Classes DEA Class; Rx Common Brand Names; Denavir Antivirals, Topical Description Topical antiviral medication; active metabolite of famciclovirFor treatment of herpes labialis in patients 12 years and olderMore favorable results than with topical acyclovir Indications Indicated for the treatment of recurrent herpes labialis. Contraindications Hypersensitivity Adverse Effects Milde erythema Application site reaction (1%) Headache…
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Ganciclovir
Brands Classes DEA Class; Rx Common Brand Names; Cytovene, Vitrasert DSC, Zirgan Antivirals, CMV; Ophthalmic Description Synthetic purine nucleoside analog antiviralUsed for prevention and treatment of CMV; ophthalmic gel approved for acute herpetic keratitisDose adjustment may be required for hematological toxicity (neutropenia, thrombocytopenia) Indications Indicated for the treatment of cytomegalovirus (CMV) retinitis in immunocompromised adults,…
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Foscarnet
Brands Classes DEA Class; Rx Common Brand Names; Foscavir, Phosphonoformic acid Antivirals, CMV; Antivirals, Other Description Antiviral agent; organic analog of inorganic pyrophosphate; not associated with myelosuppression; does not require phosphorylation for activation; used in CMV, herpes simplex, and varicella-zoster. Indications Patients with AIDS: Combination therapy with ganciclovir indated for patients who have relapsed following…
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Famciclovir
Brands Classes DEA Class; Rx Common Brand Names; Famvir Antivirals, Other Description Oral antiviral agent; prodrug for penciclovirIndicated for tx of acute herpes zoster, tx or suppression of recurrent genital herpes in immunocompetent patients, acute tx of recurrent herpes labialis in immunocompetent patients, and tx of recurrent mucocutaneous herpes simplex infection in HIV patientsSimilar spectrum…
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Cidofovir
Brands Classes DEA Class; Rx Common Brand Names; Vistide (DSC) Antivirals, CMV Description Antiviral; acyclic phosphonate nucleotide analog; structurally similar to acyclovir; not dependent upon intracellular activationUsed for the treatment of cytomegalovirus (CMV), herpes virus infections, and adenovirus infectionsAssociated with renal toxicity; use with probenecid and IV hydration to reduce toxicity Indications Indicated for the…
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Acyclovir
Brands Classes DEA Class; Rx Common Brand Names; Zovirax, Avaclyr, Zovirax topical, Sitavig Antivirals, Other; Antivirals, HSV; Antivirals, VZV Description Synthetic antiviral with activity against herpes simplex virus type 1 and 2 and varicella-zoster virusUsed to treat herpes labialis, herpes genitalis, herpes simplex encephalitis, herpes simplex keratitis, neonatal herpes infection, chickenpox (varicella), shingles (zoster)Potent activity…