Tag: For Hepatic Viral Infections: Hepatitis C

Brands Classes DEA Class; Rx Common Brand Names; Vosevi HCV NS5A Inhibitors;  HCV Polymerase Inhibitors;  HCV Protease Inhibitors Description Combination oral antiviralUsed for the treatment of chronic hepatitis C infection in treatment-experienced adults without cirrhosis or with compensated cirrhosis (Child-Pugh A)Risk of hepatitis B virus (HBV) reactivation has been reported in some cases resulting in…

Brands Classes DEA Class; Rx Common Brand Names; Epclusa HCV NS5A Inhibitors;  HCV Polymerase Inhibitors Description Combination oral productUsed to treat adults and pediatric patients 3 years and older infected with chronic hepatitis C virus (HCV), with and without cirrhosisFirst regimen approved for all HCV genotypes Indications Indicated for chronic hepatitis C virus (HCV) infection…

Brands Classes DEA Class; Rx Common Brand Names; Sovaldi Hepatitis B/Hepatitis C Agents;  HCV Polymerase Inhibitors Description Hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitorFor chronic hepatitis C infection, genotypes 1, 2, 3, and 4, in adult patients and genotypes 2 and 3 in pediatric patients 3 years and older, including those with hepatocellular…

Brands Classes DEA Class; Rx Common Brand Names; Technivie NS3/4A Protease Inhibitor Antivirals in Combination with NS5A Protein Inhibitor Antivirals for Hepatitis C Description 3 drug oral combination product including a HCV NS5A inhibitor, a NS3/4A protease inhibitor, and a pharmacokinetic enhancerFor use with ribavirin in the treatment of genotype 4 hepatitis C virus (HCV)…

Discontinued Classes DEA Class; Rx Common Brand Names; Viekira Pak (DSC) HCV NS5A Inhibitors;  HCV Polymerase Inhibitors;  HCV Protease Inhibitors Description Combination oral product containing 3 antivirals with activity against HCV and a pharmacokinetic enhancerFor HCV genotype 1a and 1b, including patients with and without compensated cirrhosisContraindicated in patients with moderate to severe hepatic disease…

Brands Classes DEA Class; Rx Common Brand Names; Harvoni HCV NS5A Inhibitors;  HCV Polymerase Inhibitors Description Combination antiviral containing a hepatitis C virus (HCV) NS5A protein inhibitor and a nucleotide analog HCV NS5B polymerase inhibitorUsed to treat chronic HCV genotype 1, 4, 5, and 6 infections in adults and pediatric patients 3 years and olderBlack…

Brands Classes DEA Class; Rx Common Brand Names; Mavyret HCV NS5A Inhibitors;  HCV NS3/4A Protease Inhibitors Description Combination oral antiviral containing an HCV NS3/4A protease inhibitor and NS5A inhibitorFor the treatment of chronic HCV infections (all genotypes) in adults and pediatric patients 3 years and older without cirrhosis or with compensated cirrhosis (Child-Pugh A)Contraindicated in…

Brands Classes DEA Class; Rx Common Brand Names; Zepatier HCV NS5A Inhibitors;  HCV NS3/4A Protease Inhibitors Description Combination product containing an NS5A inhibitor (elbasvir) and an NS3/4A protease inhibitor (grazoprevir)Used to treat adults and pediatric patients weighing at least 30 kg with HCV genotypes 1 and 4 infectionsContraindicated in patients with moderate to severe hepatic…

Brands Classes DEA Class; Rx Common Brand Names; Daklinza NS5A Protein Inhibitor Antivirals for Hepatitis C Description Hepatitis C virus (HCV) NS5A inhibitorFor use with sofosbuvir and with or without ribavirin to treat genotypes 1 and 3 chronic HCV infectionsConsider testing for NS5A resistance-associated polymorphisms prior to treating cirrhotic patients with HCV genotype 1a infections…