Tag: Drugs for Peptic Ulcer Disease
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Sucralfate
Brands Classes DEA Class; OTC Common Brand Names; Carafate Gastrointestinal Agents, Other Description Oral aluminum-containing sucrose sulfate complex; forms adherent, protective barrier at sites of damaged GI mucosa, shields mucosa from pepsin, acid, and bile; used for esophagitis, GERD, GI ulceration, and stomatitis. Indications Indicated for the treatment of duodenal ulcer not related to NSAID…
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Citric Acid/Sodium Bicarbonate
Brands Classes DEA Class; OTC Common Brand Names; Alka-Seltzer Heartburn Relief Antacids, Combos Description Citric acid: Antacid; forms sodium citrate which neutralizes stomach acid Sodium bicarbonate: Antacid; reacts with and neutralizes hydrochloric acid in the stomach Indications Indicated for Indigestion/Heartburn Contraindications — Adverse Effects — Warnings Sodium-restricted diet; 575 mg sodium/tablet Phenylketonurics; contains phenylalanine 5.6…
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Sodium Bicarbonate (Antidote)
Brands Classes DEA Class; Rx Common Brand Names; Antidotes, Other Description Increases blood and urinary pH by releasing a bicarbonate ion, which in turn neutralizes hydrogen ion concentrations 1g of sodium bicarbonate is equivalent to 11.9 mEq each of sodium and bicarbonate Indications Indicated for Cocaine Toxicity Cyanide Toxicity Salicylate Toxicity Barbiturate Toxicity Cardiac Arrest…
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Sodium Bicarbonate
Brands Classes DEA Class; OTC Common Brand Names; Alkalinizing Agents Description Bicarbonate reacts with H+ ions to form water & carbon dioxide. It acts as a buffer against acidosis by raising blood pH Indications Indicated for Cardiac Arrest Hyperkalemia Metabolic Acidosis Contraindications Hypersensitivity Injection Chloride loss due to vomiting or from continuous gastrointestinal suction Currently…
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Aluminum Hydroxide/Magnesium Carbonate
Brands Classes DEA Class; OTC Common Brand Names; Gaviscon Extra Strength Liquid, Gaviscon Extra Strength Tablets, Gaviscon Regular Strength Liquid Antacids, Combos Description Neutralizes gastric acid, increases gastric pH Indications Indicated for Gastric Hyperacidity, Heartburn Contraindications Hypersensitivity Adverse Effects Aluminum Chalky taste Constipation Fecal impaction Stomach cramps Nausea Vomiting Aluminum intoxication Hypophosphatemia Osteomalacia Magnesium Diarrhea Hypermagnesemia…
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Aluminum Hydroxide/Magnesium Trisilicate
Brands Classes DEA Class; OTC Common Brand Names; Gaviscon Regular Strength Tablets Antacids, Combos Description Neutralizes gastric acid, increases gastric pH Indications Indicated for Gastric Hyperacidity, Heartburn Contraindications Hypersensitivity Adverse Effects Aluminum hydroxide Chalky taste Constipation Fecal impaction Stomach cramps Nausea Vomiting Aluminum intoxication Hypomagnesemia Hypophosphatemia Osteomalacia Magnesium Trisilicate Diarrhea Hypermagnesemia Nausea Vomiting Headache Dizziness…
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Aluminum Hydroxide/Magnesium Hydroxide
Brands Classes DEA Class; OTC Common Brand Names; Maalox Antacids, Combos Description Neutralizes gastric acid, increases gastric pH Indications Indicated for Gastric Hyperacidity, Heartburn Contraindications Hypersensitivity to any component Adverse Effects Aluminum oxide Chalky taste Constipation Fecal impaction Stomach cramps Nausea Vomiting Aluminum intoxication Hypophosphatemia Osteomalacia Magnesium oxide Diarrhea Hypermagnesemia Warnings Prolonged antacid therapy may…
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Aluminum Hydroxide/Magnesium Hydroxide/Simethicone
Brands Classes DEA Class; OTC Common Brand Names; Mylanta, Mygel, DiGel, Gelusil, Rulox Antacids, Combos Description Aluminum hydroxide: Neutralizes stomach hydrochloride to form AlCl3 salt plus water; increases gastric pH Magnesium hydroxide: Promotes bowel evacuation by causing osmotic retention of fluid, which causes the colon to distend with increased peristaltic activity; forms magnesium chloride when reacts…
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Aluminum Hydroxide
Brands Classes DEA Class; OTC Common Brand Names; AlternaGEL, Amphojel, Nephrox Antacids Description Antacid; some use for hyperphosphatemia; there is concern regarding Al++ toxicity with long-term use as a phosphate ‘binder’, thus use is limited to patients with high serum phosphate (7mg/dL). Not a primary treatment for PUD. Indications Indicated for use as an antacid to…
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Rabeprazole
Brands Classes DEA Class; Rx Common Brand Names; Aciphex, Aciphex Sprinkle Proton Pump Inhibitors Description Proton pump inhibitor (PPI); gastric antisecretory agentUsed for GERD, peptic ulcer disease, in combination with antibiotics for the eradication of H. pylori, and for hypersecretory conditions such as ZE syndromeMay have less potential for drug interactions compared to other PPIs…
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Pantoprazole
Brands Classes DEA Class; Rx Common Brand Names; Protonix Proton Pump Inhibitors Description Oral and IV gastric proton-pump inhibitor (PPI)Used for erosive esophagitis, GERD, Zollinger-Ellison syndrome, duodenal and gastric ulcers, H. pylori eradication with antibiotics, and stress ulcer prophylaxisLowest propensity of PPIs for CYP-based drug interactions Indications Indicated for the treatment of Erosive Esophagitis Associated…
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Omeprazole/Sodium Bicarbonate
Brands Classes DEA Class; Rx, OTC Common Brand Names; Zegerid, Zegerid OTC, Konvomep Antacids, Combos; Proton Pump Inhibitors Description Oral immediate-release proton pump inhibitor (PPI) combined with a sodium bicarbonate bufferPrescription products used for GERD, erosive esophagitis, gastric and duodenal ulcer, and stress ulcer prophylaxis in critically ill patientsNonprescription products used for short-term use (14 days)…
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Omeprazole
Brands Classes DEA Class; Rx, OTC Common Brand Names; Prilosec, Prilosec OTC, OmepraCare, OmepraCare DR Proton Pump Inhibitors Description Oral proton pump inhibitor (PPI), gastric antisecretory agent.Used for GERD, erosive esophagitis, and hypersecretory conditions; also used in antimicrobial combination regimens for H. pylori eradication.Available OTC for heartburn. Indications Indicated for the short-term, self-treatment of frequent dyspepsia…
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Lansoprazole
Brands Classes DEA Class; Rx, OTC Common Brand Names; Prevacid, Prevacid Solu Tab, Prevacid 24HR Proton Pump Inhibitors Description Proton-pump inhibitor (PPI), gastric antisecretory agentUsed for treatment of duodenal and gastric ulcers, erosive esophagitis, GERD, heartburn, ZE syndrome, and NSAID-induced ulcers; combined with antibiotics for eradication of H. pyloriAssociated with increased risk of Clostridium difficile-associated diarrhea…
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Esomeprazole
Brands Classes DEA Class; Rx, OTC Common Brand Names; Nexium, Nexium 24HR Proton Pump Inhibitors Description Proton pump inhibitor; S-isomer of omeprazoleUsed for GERD, NSAID-induced ulcer healing and prevention, erosive esophagitis, H. pylori eradication, upper GI rebleeding prophylaxis after therapeutic endoscopy, and hypersecretory conditions; available OTC for short-term treatment of heartburnAvoid concomitant use with clopidogrel;…