Tag: Drugs for Osteoporosis

Brands Classes DEA Class; Rx Common Brand Names; Reclast, Zometa Calcium Metabolism Modifiers;  Bisphosphonate Derivatives Description Potent third-generation intravenous bisphosphonate; carefully select product based on indication for useUsed for hypercalcemia of malignancy and bone metastases (e.g., Zometa); given as a single dose for Paget’s disease (e.g., Reclast)Given once-yearly for osteoporosis and corticosteroid-induced osteoporosis and prevention…

Brands Classes DEA Class; Rx Common Brand Names; Forteo, parathyroid hormone, Bonsity Parathyroid Hormone Analogs Description Recombinant human parathyroid hormoneUsed for the treatment of osteoporosis in patients with high risk of fractureBoxed warning regarding the risk of osteosarcoma; not recommended for use in patients at risk for osteosarcoma Indications Treatment of postmenopausal women with osteoporosis at…

Brands Classes DEA Class; Rx Common Brand Names; Boniva Calcium Metabolism Modifiers;  Bisphosphonate Derivatives Description Potent oral and parenteral third-generation bisphosphonatePrimarily used for treatment and prevention of postmenopausal osteoporosis; increases bone mineral density and reduces vertebral fracture risk; consider if spine-specific osteoporosis therapy neededUsed off-label for hypercalcemia of malignancy and for reduction of skeletal events…

Brands Classes DEA Class; Rx Common Brand Names; Miacalcin Calcium Metabolism Modifiers Description Subcutaneously administered monoclonal antibody against human RANKLProlia is used for treatment of osteoporosis in men and postmenopausal women, and for osteoporosis prophylaxis in women with breast cancer and men with nonmetastatic prostate cancerXgeva is used for prevention of skeletal-related events due to…

Brands Classes DEA Class; Rx Common Brand Names; Miacalcin Calcium Metabolism Modifiers Description Peptide hormone secreted by the C cells in the thyroid gland; binds directly to a receptor on the osteoclast surface to inhibit bone resorption; lowers serum calciumSynthetic salmon calcitonin is more potent and longer-acting than human calcitoninDue to lower efficacy vs. other…

Brands Classes DEA Class; Rx Common Brand Names; Fosamax, Binosto, Fosamax Plus D Calcium Metabolism Modifiers;  Bisphosphonate Derivatives Description Oral second-generation bisphosphonate; weekly or daily regimens available for selected conditionsUsed primarily for treatment and prevention of osteoporosis in both men and postmenopausal women; also indicated for corticosteroid-induced osteoporosisAlso used for adults with Paget’s disease Indications Postmenopausal…

Brands Classes DEA Class; Rx Common Brand Names; Tymlos Parathyroid Hormone Analogs Description An analog of human parathyroid hormone related peptide [PTHrP(1-34)]Used for the treatment of postmenopausal women with osteoporosis at high risk for fractureCumulative use for more than 2 years during a patient’s lifetime is not recommended Indications Women Indicated for treatment of osteoporosis…