Tag: Drugs for neurodegenerative diseaes

  • Carbidopa/Levodopa

    Brands Classes DEA Class;  Rx Common Brand Names; Sinemet, Rytary, Duopa, Dhivy, Sinemet CR (DSC) Decarboxylase Inhibitors;  Antiparkinson Agents, Dopamine Precursors Description Combination product of dopamine precursor (levodopa) with a decarboxylase inhibitor (carbidopa)Used for idiopathic Parkinson’s disease, post-encephalitic parkinsonism, and symptomatic parkinsonism following injury to the nervous system; various formulations help with individualization of dosingAn enteral…

  • Carbidopa

    Brands Classes DEA Class;  Rx Common Brand Names; Lodosyn Decarboxylase Inhibitors Description Decarboxylase inhibitor; prevents the peripheral conversion of levodopa to dopamine; more levodopa is then available for entry into the CNS in the treatment of Parkinson’s disease. Indications For use with carbidopa-levodopa or with levodopa for Parkinson’s disease in patients for whom the dosage…

  • Bromocriptine

    Brands Classes DEA Class;  Rx Common Brand Names; Cycloset, Parlodel  Antiparkinson Agents, Dopamine Agonists;  Hyperprolactinemia;  Metabolic & Endocrine, Other Description Synthetic oral dopamine agonist; chemically related to ergot alkaloidsUsed in adult and pediatric patients 11 years and older with selected conditions such as acromegaly, a variety of hyperprolactinemia syndromes, and prolactin-secreting pituitary adenomas; micronized product…

  • Apomorphine

    Brands Classes DEA Class;  Rx Common Brand Names; Apokyn, Kynmobi Antiparkinson Agents, Dopamine Agonists Description Non-narcotic morphine derivative; dopamine agonist with potent emetic propertiesApproved as a sublingual film for acute, intermittent ‘off’ episodes associated with Parkinson’s disease; subcutaneous injection approved in advanced Parkinson’s diseaseMonitor for hypotension, orthostasis, new or worsening impulse control symptoms, and patient…

  • Amantadine

    Brands Classes DEA Class;  Rx Common Brand Names; Osmolex ER, Gocovri  Antiparkinson Agents, Dopamine Agonists;  Antivirals, Influenza Description Synthetic antiviral agent with dopamine agonist properties Used primarily for motor symptoms of Parkinson’s disease (PD) or drug-induced EPS; an extended-release product can be used as an adjunct to carbidopa-levodopa in PD patients experiencing ‘off’ episodes Not…