Tag: Drugs for neurodegenerative diseaes
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Carbidopa/Levodopa
Brands Classes DEA Class; Rx Common Brand Names; Sinemet, Rytary, Duopa, Dhivy, Sinemet CR (DSC) Decarboxylase Inhibitors; Antiparkinson Agents, Dopamine Precursors Description Combination product of dopamine precursor (levodopa) with a decarboxylase inhibitor (carbidopa)Used for idiopathic Parkinson’s disease, post-encephalitic parkinsonism, and symptomatic parkinsonism following injury to the nervous system; various formulations help with individualization of dosingAn enteral…
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Carbidopa
Brands Classes DEA Class; Rx Common Brand Names; Lodosyn Decarboxylase Inhibitors Description Decarboxylase inhibitor; prevents the peripheral conversion of levodopa to dopamine; more levodopa is then available for entry into the CNS in the treatment of Parkinson’s disease. Indications For use with carbidopa-levodopa or with levodopa for Parkinson’s disease in patients for whom the dosage…
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Bromocriptine
Brands Classes DEA Class; Rx Common Brand Names; Cycloset, Parlodel Antiparkinson Agents, Dopamine Agonists; Hyperprolactinemia; Metabolic & Endocrine, Other Description Synthetic oral dopamine agonist; chemically related to ergot alkaloidsUsed in adult and pediatric patients 11 years and older with selected conditions such as acromegaly, a variety of hyperprolactinemia syndromes, and prolactin-secreting pituitary adenomas; micronized product…
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Apomorphine
Brands Classes DEA Class; Rx Common Brand Names; Apokyn, Kynmobi Antiparkinson Agents, Dopamine Agonists Description Non-narcotic morphine derivative; dopamine agonist with potent emetic propertiesApproved as a sublingual film for acute, intermittent ‘off’ episodes associated with Parkinson’s disease; subcutaneous injection approved in advanced Parkinson’s diseaseMonitor for hypotension, orthostasis, new or worsening impulse control symptoms, and patient…
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Amantadine
Brands Classes DEA Class; Rx Common Brand Names; Osmolex ER, Gocovri Antiparkinson Agents, Dopamine Agonists; Antivirals, Influenza Description Synthetic antiviral agent with dopamine agonist properties Used primarily for motor symptoms of Parkinson’s disease (PD) or drug-induced EPS; an extended-release product can be used as an adjunct to carbidopa-levodopa in PD patients experiencing ‘off’ episodes Not…