Tag: Drugs for neurodegenerative diseaes

Brands Classes DEA Class;  Rx Common Brand Names; Decadron DSC, Dexamethasone Intensol, Baycadron, Hemady Corticosteroids;  Anti-Inflammatory Agents Dexamethasone ophthalmic; Maxidex Corticosteroids, Ophthalmic Dexamethasone ophthalmic insert; Dextenza Corticosteroids, Ophthalmic Dexamethasone intraocular; Dexycu Corticosteroids, Ophthalmic Dexamethasone intravitreal implant; Ozurdex Corticosteroids, Ophthalmic   Description Cytoprotective agentUsed to reduce the incidence and severity of cardiomyopathy associated with doxorubicin administration in…

Brands Classes DEA Class;  Rx Common Brand Names; Ampyra Multiple Sclerosis Treatments;  Potassium Channel Blockers;  Cholinergic Agonists Description Oral potassium channel blocker, also known as 4-aminopyridineIndicated to improve walking in adult patients with multiple sclerosis (MS); results are independent of immunomodulatory drug therapiesMajor dose-limiting side effect is seizures; patients with moderate to severe renal dysfunction…

Generic Only Classes DEA Class;  Rx Common Brand Names; ZINBRYTA Interleukin-2 (IL-2) InhibitorsMS Agents Description Immunosuppressant; chimeric monoclonal antibody (IgG1)Previously approved for relapsing forms of muiltiple sclerosisWithdrawn form the worldwide market due to safety concerns, including brain inflammation, hepatotoxicity, and other immune-mediated disorders Indications Indicated for the treatment of relapsing forms of multiple sclerosis. Contraindications…

Brands Classes DEA Class;  Rx Common Brand Names; Cytoxan Antineoplastics, Alkylating;  DMARDs, Immunomodulators Description Alkylating agent; has activity as both an antineoplastic and immunosuppressantUsed for the treatment of a variety of solid tumors, NHL, Hodgkin lymphoma, and ALL; oral cyclophosphamide used for nephrotic syndrome in pediatric patients; several off-label usesContraindicated in patients with urinary outflow…

Brands Classes DEA Class;  Rx Common Brand Names; Azasan, Imuran DMARDs, Immunomodulators;  Immunosuppressants Description Oral and parenteral thiopurine immunosuppressive agent; metabolized to 6-mercaptopurineCommonly used in transplant patients but also is useful in RA, lupus nephritis, and psoriatic arthritisIn gastroenterology, used in the treatment of Crohn’s disease and ulcerative colitis Indications Indicated for kidney transplant rejection…

Brands Classes DEA Class;  Rx Common Brand Names; Campath, Lemtrada  Antineoplastics, Monoclonal Antibody;  Multiple Sclerosis Treatments Description Humanized monoclonal antibody against the CD52 antigenOne product, Lemtrada, is used for relapsing forms of multiple sclerosis (MS) but is reserved for those with inadequate response to 2 or more drugs due to risk for serious side effectsThe…

Brands Classes DEA Class;  Rx Common Brand Names; Namenda XR, Namenda NMDA Antagonists Description Oral N-methyl-D-aspartate (NMDA) receptor antagonistFor use in moderate to severe Alzheimer’s disease both as monotherapy and with donepezil; may provide small cognitive benefit in mixed dementia and dementia with Lewy bodiesMedical conditions, drugs, or foods that raise urine pH may decrease…

Brands Classes DEA Class;  Rx Common Brand Names; Tasmar Antiparkinson Agents, COMT Inhibitors Description Peripheral and centrally acting oral COMT inhibitor; improves levodopa availability in the CNS; more potent than entacaponeUsed for adults with Parkinson’s disease as an adjunct to levodopa/carbidopaLess favorable side effect profile vs. entacapone; boxed warning exists in labeling for hepatotoxicity and…

Brands Classes DEA Class;  Rx Common Brand Names; Eldepryl, Zelapar, Emsam  Antiparkinson Agents, MAO Type B Inhibitors Description Selective type-B monoamine oxidase inhibitor (MAOI) available orally and as a transdermal patchOral formulations used as an adjunct treatment in Parkinson’s disease; transdermal patch approved for major depressive disorder in adultsTyramine reactions, such as hypertensive crisis, are…

Brands Classes DEA Class;  Rx Common Brand Names; Xadago Antiparkins Agents, Adjunct;  Antiparkinson Agents, MAO Type B Inhibitors Description Selective and reversible inhibitor of monoamine oxidase (MAO) Type BUsed as an adjunct to levodopa; carbidopa therapy to treat “off” episodes in adults with Parkinson’s diseaseAlthough MAO-B selectivity of the drug is high, patients should be…

Brands Classes DEA Class;  Rx Common Brand Names; Neupro Antiparkinson Agents, Dopamine Agonists Description Non-ergoline dopamine agonist; transdermal patch formulationUsed for early and advanced Parkinson’s disease and restless legs syndromeMay cause abrupt onset of sleep or excessive drowsiness resulting in serious harm Indications Indicated for the treatment of the signs and symptoms of idiopathic Parkinson’s disease.…

Brands Classes DEA Class;  Rx Common Brand Names; Requip, Requip XL Antiparkinson Agents, Dopamine Agonists Description Oral non-ergot-derived dopamine agonistUsed for Parkinson’s disease and moderate to severe restless legs syndrome (RLS) in adultsMonitor for hallucinations, psychotic-like behavior, impulse control symptoms, and sleep attacks Indications Indicated for the treatment of Parkinson’s disease. For the treatment of…

Brands Classes DEA Class;  Rx Common Brand Names; Azilect Antiparkinson Agents, MAO Type B Inhibitors Description Second generation, irreversible MAOI-B; for early treatment of Parkinson’s disease as monotherapy and for later disease as adjunct therapy to levodopa; typical MAOI dietary tyramine precautions not required for most foods/beverages when used at manufacturer recommended doses; dopaminergic adverse…

Brands Classes DEA Class;  Rx Common Brand Names; Mirapex, Mirapex ER Antiparkinson Agents, Dopamine Agonists Description Oral non-ergot-derived dopamine agonistUsed for Parkinson’s disease and moderate to severe restless legs syndrome (RLS) in adultsMonitor for hallucinations, psychotic-like behavior, impulse control symptoms, and sleep attacks Indications Indicated for the treatment of moderate to severe primary Restless Legs…

Brands Classes DEA Class;  Rx Common Brand Names; Stalevo Antiparkinson Agents, COMT Inhibitors;  Decarboxylase Inhibitors;  Antiparkinson Agents, Dopamine Precursors Description Oral combination of levodopa-carbidopa therapy with a COMT inhibitor (entacapone)Used for adults with Parkinson’s diseaseAddition of a COMT inhibitor helpful for patients whoexperience the end-of dose ‘wearing off’ effect of levodopa Indications Indicated for the…