Tag: Drugs for neurodegenerative diseaes

  • Chlordiazepoxide/Clidinium

    Brands Classes DEA Class;  Rx Common Brand Names; Librax Gastrointestinal Agents, Other Description Oral benzodiazepine/antimuscarinic combination Used to control emotional and somatic factors in gastrointestinal disorders and for adjunct treatment for irritable bowel syndrome and peptic ulcer disease Common ADRs include anticholinergic effects and drowsiness Indications Indicated to control emotional and somatic factors in gastrointestinal disorders, for…

  • Riluzole

    Brands Classes DEA Class;  Rx Common Brand Names; Rilutek, Tiglutik, Exservan Glutamate Inhibitors Description Oral glutamate antagonistUsed for treatment of amyotrophic lateral sclerosis (ALS)Does not cure disease or improve symptoms, but may prolong survival by 3 months Indications Indicated for the treatment of amyotrophic lateral sclerosis (ALS). For the treatment of chorea associated with Huntington’s Disease…

  • Edaravone

    Brands Classes DEA Class;  Rx Common Brand Names; Radicava, Radicava ORS Neurologics, Other Description Oral and intravenous antioxidantUsed for treatment of amyotrophic lateral sclerosis (ALS)Hypersensitivity reactions, including anaphylaxis, reported Indications Indicated for amyotrophic lateral sclerosis (ALS) Contraindications Hypersensitivity to drug or any of its excipients Adverse Effects Contusion (15%) Gait disturbance (13%) Headache (10%) Dermatitis…

  • Teriflunomide

    Brands Classes DEA Class;  Rx Common Brand Names; Aubagio Multiple Sclerosis Treatments;  Pyrimidine Synthesis Inhibitors Description Oral pyrimidine synthesis inhibitor; an active metabolite of leflunomideUsed in adults with relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive diseaseBoxed warnings regarding risk for hepatotoxicity and for teratogenicity Indications Indicated for…

  • Prednisone

    Brands Classes DEA Class;  Rx Common Brand Names; Deltasone, Rayos, Prednisone Intensol, Sterapred, Sterapred DS Corticosteroid Description Commonly-prescribed oral corticosteroid with little mineralocorticoid activity; metabolized to prednisolone; prednisone is roughly 4 times as potent as hydrocortisone as a glucocorticoidUsed in many conditions in adult and pediatric patients, including asthma, COPD, SLE, rheumatoid and psoriatic arthritis, prevention…

  • Ocrelizumab

    Brands Classes DEA Class;  Rx Common Brand Names; Ocrevus  Monoclonal Antibodies;  Multiple Sclerosis Treatments Description CD20-directed cytolytic monoclonal antibody which targets B-cellsUsed in adults for primary progressive MS and relapsing forms of MS, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive diseaseInfusion reactions are common; pre-medication is needed prior to infusion Indications…

  • Natalizumab

    Brands Classes DEA Class;  Rx Common Brand Names; Tysabri  Multiple Sclerosis Treatments;  Inflammatory Bowel Disease Agents;  Monoclonal Antibodies, Integrin Blockers Description Humanized monoclonal antibody against alpha-4 integrin; an alpha-4-integrin inhibitorUsed in adults for relapsing forms of multiple sclerosis and induces and maintains remission in moderately to severely active Crohn’s DiseaseOnly available via the TOUCH Prescribing…

  • Interferon Beta 1b

    Brands Classes DEA Class;  Rx Common Brand Names; Betaseron, Extavia Immunomodulators;  Multiple Sclerosis Treatments Description Recombinant interferon beta; not glycosylatedIndicated for relapsing forms of multiple sclerosis, such as clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive diseaseMay increase the risk for depression, suicidal ideation, and suicide attempts Indications Indicated for treatment of relapsing forms…

  • Interferon beta 1a

    Brands Classes DEA Class;  Rx Common Brand Names; Avonex, Rebif, Rebif Rebidose, AVOSTARTGRIP Immunomodulators;  Multiple Sclerosis Treatments Description Recombinant, glycosylated interferon beta; identical amino acid sequence to endogenous interferon betaIndicated for relapsing forms of multiple sclerosis, such as clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive diseaseMay increase the risk for depression, suicidal ideation, and…

  • Glatiramer

    Brands Classes DEA Class;  Rx Common Brand Names; Copaxone, Glatopa  Immunomodulators;  Multiple Sclerosis Treatments Description Synthetic random peptide given subcutaneously; formerly known as copolymer-1Used in adults with relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease; also used off-label in pediatric patientsImmediate post-injection reactions (flushing, chest pain, dyspnea,…

  • Fingolimod

    Brands Classes DEA Class;  Rx Common Brand Names; Gilenya, Tascenso ODT Immunomodulators;  Multiple Sclerosis Treatments;  Sphingosine 1-Phosphate Receptor Modulators Description Oral sphingosine 1-phosphate receptor modulatorUsed for the treatment of relapsing forms of multiple sclerosis in adults and pediatric patients 10 years and olderHypersensitivity, cardiac or ocular conditions, or severe hepatic disease may preclude treatment with…

  • Dimethyl Fumarate

    Brands Classes DEA Class;  Rx Common Brand Names; Tecfidera, BG-12 Immunomodulators;  Multiple Sclerosis Treatments Description Anti-inflammatory agent and inducer of the nuclear 1 factor (erythroid- derived 2)–like 2 (Nrf2) antioxidant response pathwayUsed for the treatment of adults with relapsing forms of multiple sclerosisOral agent with unique neuroprotective properties Indications Indicated for the treatment of relapsing…

  • Dexamethasone/Neomycin/Polymyxin

    Brands Classes DEA Class;  Rx Common Brand Names; Maxitrol, Dexasporin Antibiotics/Corticosteroids, Ophthalmic   Description Ophthalmic suspension or ointment for inflammatory and antibacterial combinationUsed for inflammatory conditions of the eyes where there is high risk of infection or where infection coexists Indications Indicated for steroid-responsive inflammatory eye conditions in which dexamethasone is indicated & where bacterial…

  • Dexamethasone/Tobramycin

    Brands Classes DEA Class;  Rx Common Brand Names; TobraDex, TobraDex ST Antibiotics/Corticosteroids, Ophthalmic   Description Topical ophthalmic corticosteroid and aminoglycoside combinationUsed for corticosteroid-responsive inflammatory ocular conditions that coexist with superficial bacterial infectionsLocalized adverse events most common Indications Indicated For the treatment of corticosteroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial…

  • Dexamethasone/Ciprofloxacin

    Brands Classes DEA Class;  Rx Common Brand Names; Ciprodex Antibiotics/Corticosteroids, Otic   Description Fluoroquinolone/corticosteroid combination otic suspension used for the topical treatment of selected ear infections, including acute otitis media due to susceptible organisms in children with tympanostomy tubes aged 6 months and older; also used for acute otitis externa (e.g., swimmer’s ear). Indications Indicated…