Tag: Drugs for Diabetes
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Canagliflozin
Brands Classes DEA Class; Rx Common Brand Names; Invokana Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitus; also provides cardiovascular (CV) risk reduction if CV disease also present; if diabetic nephropathy with albuminuria is present, the drug reduces the risk of end-stage kidney disease, doubling of…
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Alogliptin
Brands Classes DEA Class; Rx Common Brand Names; Nesina Antidiabetics, Dipeptyl Peptidase-IV Inhibitors Description Oral DPP-4 inhibitor given once daily; reduces breakdown of GLP-1 which increases insulin secretionUsed for type 2 diabetes mellitus in adults; mean A1C reduction 0.4 to 0.6%Used as monotherapy or in combination with other hypoglycemic agents including insulin, but not GLP-1…
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Acarbose
Brands Classes DEA Class; Rx Common Brand Names; Precose Antidiabetics, Alpha-Glucosidase Inhibitors Description Oral alpha-glucosidase inhibitor; minimal systemic absorptionUsed for the treatment of type 2 diabetes mellitusAgents in this class have only modest effects on A1C (i.e., mean 0.3% to 0.7% reduction) Indications Indicated for the treatment of type 2 diabetes mellitus as an adjunct…
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Pramlintide
Brands Classes DEA Class; Rx Common Brand Names; Symlin, SymlinPen 120, SymlinPen 60 Antidiabetics, Amylinomimetics Description Synthetic injectable amylin analogUsed primarily as an adjunct to insulin in adults with type 1 and type 2 diabetes mellitus; improves glycemic control and causes modest (0.5 to 2 kg) weight lossSlows gastric emptying, suppresses postprandial glucagon secretion Indications Indicated…
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Insulin Isophane Human/Insulin Regular Human
Brands Classes DEA Class; OTC Common Brand Names; Humulin 70/30, Novolin 70/30 Antidiabetics, Insulins Description A combination of regular insulin and intermediate-acting insulin (NPH insulin); fixed-ratio mixturesUsed for type 1 and type 2 diabetes mellitusFor type 2 diabetes, most commonly given twice daily Indications Indicated for the treatment of type 1 diabetes mellitus. For the treatment…
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Insulin Regular Human
Brands Classes DEA Class; Rx, OTC Common Brand Names; Humulin R, Novolin R, Humulin R U-500, Myxredlin Antidiabetics, Insulins; Antidiabetics, Short-Acting Insulins Description Regular insulin U-100 is short-acting insulin; concentrated regular insulin U-500 exhibits characteristics of immediate-acting insulinsUsed for type 1 and 2 diabetes mellitus in adult and pediatric patients; also used for hyperglycemic crises and…
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Insulin NPH
Brands Classes DEA Class; OTC Common Brand Names; Humulin N, Novolin N Antidiabetics, Insulins; Antidiabetics, Intermediate-Acting Insulins Description Intermediate-acting insulin with a longer onset and duration of activity when compared to regular insulinUsed in adult and pediatric patients with type 1 and type 2 diabetes mellitusUsually requires 2 or more injections/day when used as a…
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Insulin Lispro Protamine/Insulin Lispro
Brands Classes DEA Class; Rx Common Brand Names; Humalog Mix 50/50, Humalog Mix 50/50 Kwikpen, Humalog Mix 75/25, Humalog Mix 75/25 Kwikpen Antidiabetics, Insulins Description A combination of insulin lispro and insulin lispro protamine; fixed-ratio mixturesUsed for type 1 and type 2 diabetes mellitusFor type 2 diabetes, most commonly given twice daily Indications Indicated for the…
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Insulin Lispro
Brands Classes DEA Class; Rx Common Brand Names; Admelog, Humalog, Humalog Kwikpen, Humalog Junior KwikPen, Admelog Solostar, insulin lispro-aabc, Lyumjev Antidiabetics, Insulins; Antidiabetics, Rapid-Acting Insulins Description Rapid-acting insulin analog with a quicker onset/shorter duration of action than regular insulinUsed to improve glycemic control in adult and pediatric patients with diabetes; often given as prandial or snack…
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Insulin Glulisine
Brands Classes DEA Class; Rx Common Brand Names; Apidra, Apidra Solostar Antidiabetics, Insulins; Antidiabetics, Rapid-Acting Insulins Description Rapid-acting insulin analogUsed in the treatment of type 1 and type 2 diabetes mellitusQuicker onset and shorter duration of action when compared to regular insulin Indications Diabetes Mellitus Type I or II Indicated to improve glycemic control in…
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Insulin Glargine/Lixisenatide
Brands Classes DEA Class; Rx Common Brand Names; Soliqua 100/33 Antidiabetics, Glucagon-like Peptide-1 Agonists; Antidiabetics, Long-Acting Insulins Description Lixisenatide: Incretin mimetic; analogue of human glucagonlike peptide-1 (GLP-1); acts as GLP-1 receptor agonist to augment glucose-dependent insulin secretion, decreases glucagon secretion, and slows gastric emptying Insulin glargine: Basal insulin analog; insulin lowers blood glucose by stimulating…
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Insulin Glargine
Brands Classes DEA Class; Rx Common Brand Names; Lantus, Lantus SoloStar, Toujeo, Basaglar, Semglee, insulin glargine-yfgn, Rezvoglar, insulin glargine-aglr Antidiabetics, Insulins; Antidiabetics, Long-Acting Insulins Description Rapid-acting insulin analogUsed in the treatment of type 1 and type 2 diabetes mellitusQquicker onset and shorter duration of action when compared to regular insulin Indications Indicated for the treatment of…
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Insulin Detemir
Brands Classes DEA Class; Rx Common Brand Names; Levemir, Levemir FlexTouch Antidiabetics, Insulins; Antidiabetics, Long-Acting Insulins Description Basal insulin analog administered subcutaneously once or twice dailyUsed for type 1 diabetes mellitus (DM) in adult and pediatric patients 2 years and older and adults with type 2 DMAdvantages vs. NPH insulin include less variability in patient…
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Liraglutide/Insulin Degludec
Brands Classes DEA Class; Rx Common Brand Names; Xultophy Antidiabetics, Glucagon-like Peptide-1 Agonists; Antidiabetics, Insulins; Antidiabetics, Long-Acting Insulins Description Subcutaneous injection with a basal insulin (insulin degludec) and a GLP-1 RA (liraglutide); given once dailyUsed in adults for type 2 diabetes mellitus; may be added to metformin in patients naive to basal insulinLiraglutide is not…
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Insulin Degludec
Brands Classes DEA Class; Rx Common Brand Names; Tresiba Antidiabetics, Insulins; Antidiabetics, Long-Acting Insulins Description Long-acting, insulin analog; given subcutaneously once dailyUsed in adult and pediatric patients 1 year and older with type 1 or type 2 diabetes mellitusProvides A1C control similar to other long-acting once-daily insulin analogs; severe, life threatening allergic reactions, including anaphylaxis,…