Tag: Drugs for Diabetes

  • Glimepiride/​Pioglitazone

    Brands Classes DEA Class; Rx Common Brand Names; Duetact Antidiabetics, Sulfonylureas/Thiazolidinediones Description Combination of pioglitazone, a thiazolidinedione, and glimepiride, a second-generation sulfonylureaUsed in adults for the treatment of type 2 diabetes mellitusMonitor patients for hypoglycemia, edema, weight gain, and heart failure Indications Indicated for management of type 2 diabetes mellitus as adjunct to diet and…

  • Glimepiride/​Rosiglitazone

    Brands Classes DEA Class; Rx Common Brand Names; Avandaryl Antidiabetics, Sulfonylureas/Thiazolidinediones Description Combination of glimepiride, a sulfonylurea, and rosiglitazone, a thiazolidinedione.Used for treatment of type 2 diabetes mellitus; combination may increase risk of hypoglycemia vs monotherapy. Indications Indicated for the treatment of type 2 diabetes mellitus uncontrolled by diet and exercise alone.NOTE: Patients treated with…

  • Glimepiride

    Brands Classes DEA Class; Rx Common Brand Names; Amaryl Antidiabetics, Sulfonylureas Description Second-generation sulfonylurea; weakly active metabolitesUsed primarily in adults for the treatment of type 2 diabetes mellitus, as add-on therapy to metformin or other agentsGlipizide is preferred over glyburide for use in the elderly and in patients with renal dysfunction, but glimepiride can also…

  • Ertugliflozin/Sitagliptin

    Brands Classes DEA Class; Rx Common Brand Names; Steglujan Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitor combination productUsed for adults with type 2 diabetes mellitus; when used with metformin, many patients achieve A1C targetsContraindicated in severe renal impairment, as ertugliflozin efficacy is reduced…

  • Ertugliflozin/Metformin

    Brands Classes DEA Class; Rx Common Brand Names; Segluromet Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitusContraindicated in severe renal impairment due to reduced ertugliflozin efficacy and increased risk of metformin-related lactic acidosis Indications Indicated as adjunct to diet…

  • Ertugliflozin

    Brands Classes DEA Class; Rx Common Brand Names; Steglatro Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed for adults with type 2 diabetes mellitusNot recommended for patients with an eGFR less than 45 mL/minute/1.73 m2 as efficacy is reduced and renal-related adverse reactions may increase Indications Indicated as an adjunct to diet and…

  • Empagliflozin/​Linagliptin/​Metformin

    Brands Classes DEA Class; Rx Common Brand Names; Trijardy XR Antidiabetics, Biguanides;  Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Empagliflozin: SGLT2 inhibitor; SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen; SGLT2 inhibitors reduce glucose reabsorption and lower the…

  • Empagliflozin/​Metformin

    Brands Classes DEA Class; Rx Common Brand Names; Synjardy, Synjardy XR Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitusContraindicated in severe renal impairment Indications Indicated for the treatment of type 2 diabetes mellitus in combination with diet and exercise…

  • Empagliflozin/Linagliptin

    Brands Classes DEA Class; Rx Common Brand Names; Glyxambi Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of a sodium-glucose co-transporter 2 (SGLT2) inhibitor combined with a dipeptidyl peptidase-4 (DPP-4) inhibitorUsed for adults with type 2 diabetes mellitus not adequately controlled on either drug alone; when used with metformin, many patients achieve target…

  • Empagliflozin

    Brands Classes DEA Class; Rx Common Brand Names; Jardiance Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitus (DM); to reduce the risk of cardiovascular (CV) death in adults with type 2 DM and established CV disease; to reduce risk of CV death and heart failure (HF)…

  • Dapagliflozin/Saxagliptin/Metformin

    Brands Classes DEA Class; Rx Common Brand Names; Qternmet XR Antidiabetics, Biguanides;  Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of a sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitorUsed for adults with type 2 diabetes mellitus; when used with metformin, patients may achieve A1C targetsContraindicated for patients with eGFR less…

  • Dapagliflozin/​Saxagliptin

    Brands Classes DEA Class; Rx Common Brand Names; Qtern Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of a sodium-glucose co-transporter 2 (SGLT2) inhibitor and dipeptidyl peptidase-4 (DPP-4) inhibitorUsed for adults with type 2 diabetes mellitus; when used with metformin, patients may achieve A1C targetsContraindicated for patients with eGFR less than 45 mL/minute/1.73…

  • Dapagliflozin/​Metformin

    Brands Classes DEA Class; Rx Common Brand Names; Xigduo XR Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed in adults with type 2 diabetes mellitus; to reduce the risk of hospitalization for heart failure in adults with T2DM and established CV disease or multiple CV risk…

  • Dapagliflozin

    Brands Classes DEA Class; Rx Common Brand Names; Farxiga Antidiabetics, SGLT2 Inhibitors Description Oral sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed for improving glycemic control in adults with type 2 diabetes mellitus (DM); reducing hospitalization for heart failure (HF) in adults with type 2 DM and established cardiovascular (CV) disease or multiple CV risk factors; reducing CV…

  • Canagliflozin/​Metformin

    Brands Classes DEA Class; Rx Common Brand Names; Invokamet, Invokamet-XR Antidiabetics, Biguanides;  Antidiabetics, SGLT2 Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed for adults with type 2 diabetes mellitusContraindicated in severe renal impairment due to reduced canagliflozin efficacy and increased risk of metformin-related lactic acidosis Indications Indicated for the treatment…