Tag: Drugs for Diabetes

Brands Classes DEA Class; Rx Common Brand Names; Actos Antidiabetics, Thiazolidinediones Description Thiazolidinedione (TZD) oral antidiabetic; targets insulin resistanceUsed in adults with type 2 diabetes mellitus; use with caution in combination with insulinMonitor closely; TZDs can cause or exacerbate heart failure (boxed warning) Indications Indicated as monotherapy or with insulin or insulin secretagogues For the…

Brands Classes DEA Class; Rx Common Brand Names; Starlix Antidiabetics, Meglitinides Derivatives Description Meglitinide oral hypoglycemic agent; stimulates insulin secretionRapid onset and short duration of action replicates physiological insulin profiles around mealsUsed prior to meals for the treatment of type 2 diabetes mellitus in adults; not commonly used as monotherapy Indications Indicated for the treatment…

Brands Classes DEA Class; Rx Common Brand Names; Glyset Antidiabetics, Alpha-Glucosidase Inhibitors Description Oral alpha-glucosidase inhibitor; in contrast to acarbose, miglitol is systemically absorbed before acting in GI tractUsed for the treatment of type 2 diabetes mellitusAgents in this class have only modest effects on A1C (i.e., mean 0.3% to 0.7% reduction) Indications Indicated for…

Brands Classes DEA Class; Rx Common Brand Names; ACTOplus Met, ACTOplus Met XR  Antidiabetics, Biguanides/Thiazolidinediones Description Oral combination of pioglitazone, a thiazolidinedione (TZD), and metformin, a biguanideUsed in adults for type 2 diabetes mellitus; use with caution with insulinRisk of lactic acidosis due to metformin is low; TZDs may cause or exacerbate heart failure; monitor…

Brands Classes DEA Class; Rx Common Brand Names; Janumet, Janumet XR Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors Description Oral combination of metformin with a sodium-glucose co-transporter 2 (SGLT2) inhibitorUsed for adults with type 2 diabetes mellitusContraindicated in severe renal impairment due to reduced canagliflozin efficacy and increased risk of metformin-related lactic acidosis Indications Indicated as an adjunct…

Brands Classes DEA Class; Rx Common Brand Names; Janumet, Janumet XR Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors Description Oral combination of a biguanide (metformin) and a dipeptidy-peptidase-4 (DPP-4) inhibitor (sitagliptin)Used in adults for the treatment of type 2 diabetes mellitusPer boxed warning the risk of lactic acidosis due to metformin requires care in prescribing and monitoring Indications…

Brands Classes DEA Class; Rx Common Brand Names; Kombiglyze XR Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors Description Oral combination of a biguanide (metformin) and a dipeptidy-peptidase-4 (DPP-4) inhibitor (saxagliptin)Used in adults for the treatment of type 2 diabetes mellitusPer boxed warning the risk of lactic acidosis due to metformin requires care in prescribing and monitoring Indications Indicated…

Brands Classes DEA Class; Rx Common Brand Names; Kazano Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors Description Oral combination of a biguanide (metformin) and a dipeptidy-peptidase-4 (DPP-4) inhibitor (alogliptin)Used in adults for the treatment of type 2 diabetes mellitusPer boxed warning the risk of lactic acidosis due to metformin requires care in prescribing and monitoring Indications Indicated as…

Brands Classes DEA Class; Rx Common Brand Names; Glucophage, Glucophage XR, Glumetza, Riomet, Riomet ER Antidiabetics, Biguanides Description Oral biguanide antidiabetic agentUsed for type 2 diabetes mellitus (T2DM) in adult and pediatric patients 10 years and older; first-line T2DM therapy generally includes metforminRisk of lactic acidosis is low but requires care in prescribing and monitoring Indications…

Brands Classes DEA Class; Rx Common Brand Names; Jentadueto, Jentadueto XR Antidiabetics, Biguanides/Dipeptyl Peptidase-IV Inhibitors Description Oral combination of a biguanide (metformin) and a dipeptidy-peptidase-4 (DPP-4) inhibitor (linagliptin)Used in adults for the treatment of type 2 diabetes mellitusPer boxed warning the risk of lactic acidosis due to metformin requires care in prescribing and monitoring Indications…

Brands Classes DEA Class; Rx Common Brand Names; Tradjenta Antidiabetics, Dipeptyl Peptidase-IV Inhibitors Description Oral DPP-4 inhibitor given once daily; reduces breakdown of GLP-1 which increases insulin secretionUsed in adults with type 2 diabetes mellitus; mean A1C reduction 0.7%Used as monotherapy or in combination with other medications, with the exception of GLP-1 agonists Indications Indicated…

Brands Classes DEA Class; Rx Common Brand Names; Glucovance Antidiabetics, Sulfonylureas/Biguanides Description Oral combination of metformin with a ‘second-generation’ sulfonylureaUsed in adults for type 2 diabetes mellitus; due to longer duration of action, glyburide is not preferred in the elderlyRisk of lactic acidosis from metformin is low but requires care in monitoring Indications Indicated for…

Brands Classes DEA Class; Rx Common Brand Names; Diabeta, Glynase, Glynase PresTab Antidiabetics, Sulfonylureas Description Second-generation sulfonylurea; twice as potent as glipizide and longer duration of actionUsed primarily in adults for the treatment of type 2 diabetes mellitusDue to longer duration of action, not a preferred sulfonylurea in the elderly Indications Indicated for the treatment of…

Brands Classes DEA Class; Rx Common Brand Names; Metaglip Antidiabetics, Sulfonylureas/Biguanides Description Oral combination of metformin with a ‘second-generation’ sulfonylureaUsed in adults for type 2 diabetes mellitus; glipizide preferred over glyburide for the elderly due to no active metabolitesRisk of lactic acidosis from metformin is low but requires care in monitoring Indications Indicated for the…

Brands Classes DEA Class; Rx Common Brand Names; Glucotrol, Glucotrol XL, Minodiab Antidiabetics, Sulfonylureas Description Second-generation sulfonylurea; shorter duration of action than glyburide; no active metabolitesUsed primarily in adults for the treatment of type 2 diabetes mellitus, as add-on therapy to metformin or other agentsGlipizide is preferred over glyburide for use in the elderly and in…