DrugsAce

Tag: Drugs for Diabetes

  • Semaglutide

    Brands Classes DEA Class; Rx Common Brand Names; Ozempic, Rybelsus, Wegovy Antidiabetics, Glucagon-like Peptide-1 Agonists Description Incretin mimetic (GLP-1 receptor agonist); available as a once-weekly subcutaneous injection or as an oral tablet given once daily; not a first-line therapy due to the boxed warning regarding rodent C-cell tumors and the uncertain risk to humansOzempic (injection) and…

  • Lixisenatide

    Brands Classes DEA Class; Rx Common Brand Names; Adlyxin Antidiabetics, Glucagon-like Peptide-1 Agonists Description Incretin mimetic (GLP-1 receptor agonist), given subcutaneously once dailyUsed in adults for type 2 diabetes mellitus as an adjunct to diet and exerciseUsed as monotherapy or with oral hypoglycemic medications or long-acting basal insulin Indications Indicated as an adjunct to diet…

  • Liraglutide

    Brands Classes DEA Class; Rx Common Brand Names; Victoza, Saxenda Antidiabetics, Glucagon-like Peptide-1 Agonists Description Subcutaneous incretin mimetic (GLP-1 receptor agonist); used once daily; not a first-line therapy due to the boxed warning regarding rodent C-cell tumors and the uncertain risk to humansVictoza product is used in adult and pediatric patients 10 years and older…

  • Exenatide Injectable Suspension

    Brands Classes Exenatide injectable solution (Rx) Brand and Other Names: Byetta Classes: Antidiabetics, Glucagon-like Peptide-1 Agonists Exenatide injectable suspension (Rx) Brand and Other Names: Bydureon BCise Classes: Antidiabetics, Glucagon-like Peptide-1 Agonists Description Subcutaneous incretin mimetic (GLP-1 receptor agonist); immediate-release injection given twice daily with meals; extended-release injection given once-weeklyExtended-release injection used to improve glycemic control in patients 10…

  • Exenatide Injectable Solution

    Brands Classes Exenatide injectable solution (Rx) Brand and Other Names: Byetta Classes: Antidiabetics, Glucagon-like Peptide-1 Agonists Exenatide injectable suspension (Rx) Brand and Other Names: Bydureon BCise Classes: Antidiabetics, Glucagon-like Peptide-1 Agonists Description Subcutaneous incretin mimetic (GLP-1 receptor agonist); immediate-release injection given twice daily with meals; extended-release injection given once-weeklyExtended-release injection used to improve glycemic control in patients 10…

  • Dulaglutide

    Brands Classes DEA Class; Rx Common Brand Names; Trulicity Antidiabetics, Glucagon-like Peptide-1 Agonists Description Incretin mimetic (GLP-1 receptor agonist) administered as a once-weekly subcutaneous injectionUsed to improve glycemic control in patients 10 years and older with type 2 diabetes mellitus (T2DM) and for the reduction of cardiovascular (CV) mortality due to major cardiovascular events (MACE)…

  • Albiglutide

    Brands Classes DEA Class; Rx Common Brand Names; Tanzeum Antidiabetics, Glucagon-like Peptide-1 Agonists Description Incretin mimetic (GLP-1 receptor agonist) administered as a once-weekly subcutaneous injectionUsed to improve glycemic control in adults with type 2 diabetes mellitusNot recommended as a first-line therapy because of the boxed warning regarding rodent C-cell tumor findings and the uncertain relevance…

  • Tolbutamide

    Brands Classes DEA Class; Rx Common Brand Names; Orinase Antidiabetics, Sulfonylureas Description First-generation oral sulfonylurea; least potent and shortest-acting sulfonylurea; lacks active metabolitesUsed in adults for the treatment of type 2 diabetes mellitus; however, second-generation agents are preferredMay be useful in the elderly or patients with renal disease Indications Indicated for adjunctive treatment of type…

  • Sitagliptin

    Brands Classes DEA Class; Rx Common Brand Names; Januvia  Antidiabetics, Dipeptyl Peptidase-IV Inhibitors Description Oral DPP-4 inhibitor given once daily; reduces the breakdown of GLP-1 which increases insulin secretionUsed in adults for type 2 diabetes mellitus; mean A1C reduction 0.65 to 1.05%Used as monotherapy or in combination with other hypoglycemic agents including insulin, but not…

  • Saxagliptin

    Brands Classes DEA Class; Rx Common Brand Names; Onglyza Antidiabetics, Dipeptyl Peptidase-IV Inhibitors Description Oral DPP-4 inhibitor given once daily; reduces breakdown of GLP-1 which increases insulin secretionUsed in adults for type 2 diabetes mellitus; mean A1C reduction 0.4 to 0.9%Used as monotherapy or in combination with other hypoglycemic agents including insulin, but not GLP-1…

  • Metformin/Rosiglitazone

    Discontinued Classes DEA Class; Rx Common Brand Names; Avandamet Antidiabetics, Biguanides/Thiazolidinediones Description Oral combination of metformin, a biguanide, and rosiglitazone, a thiazolidinedione (TZD)Used in adults for type 2 diabetes mellitus; rosiglitazone is not to be used with insulinRisk of lactic acidosis due to metformin is low; TZDs may cause or exacerbate heart failure; monitor closely…

  • Rosiglitazone

    Brands Classes DEA Class; Rx Common Brand Names; Avandia  Antidiabetics, Thiazolidinediones Description Thiazolidinedione (TZD) oral antidiabetic; targets insulin resistanceUsed in adults with type 2 diabetes mellitus; not used with insulin due to increased risks for heart failureMonitor closely; TZDs can cause or exacerbate heart failure (boxed warning) Indications Indicated as adjunct to diet and exercise…

  • Metformin/Repaglinide

    Brands Classes DEA Class; Rx Common Brand Names; PrandiMet Antidiabetics, Biguanides/Meglitinides Description Combination of a meglitinide oral antidiabetic agent, repaglinide, and the biguanide metforminUsed in adults to treat type 2 diabetes mellitus; most commonly used in patients not achieving goals with either agent aloneBoxed warning regarding lactic acidosis Indications Indicated as adjunct to diet and…

  • Repaglinide

    Brands Classes DEA Class; Rx Common Brand Names; Prandin Antidiabetics, Meglitinides Derivatives Description Meglitinide oral hypoglycemic agent; stimulates insulin secretionRapid onset and short duration of action replicates physiological insulin profiles around mealsUsed for the treatment of type 2 diabetes mellitus in adults; not commonly used as monotherapy Indications Indicated as an adjunct to diet and…

  • Alogliptin/Pioglitazone

    Brands Classes DEA Class; Rx Common Brand Names; Oseni Antidiabetics, Dipeptyl Peptidase-IV Inhibitors;  Antidiabetics, Thiazolidinediones Description Oral combination of a thiazolidinedione (pioglitazone) and a dipeptidy-peptidase-4 (DPP-4) inhibitor (alogliptin)Used for the treatment of type 2 diabetes mellitus in adultsDue to the pioglitazone component, monitor patients for edema or signs/symptoms of heart failure Indications Indicated for the…