Tag: Drugs for Bone Disorders

  • Tiludronate

    Discontinued Classes DEA Class; Rx Common Brand Names; Skelid Calcium Metabolism Modifiers;  Bisphosphonate Derivatives Description Bisphosphanate that inhibits bone resorption via actions on osteoclast activity, leading to an indirect increase in bone formation Indications Indicated for the treatment of Paget’s Disease Contraindications Hypersensitivity Inability to stand or sit upright for at least 30 minutes Abnormalities…

  • Pamidronate

    Brands Classes DEA Class; Rx Common Brand Names; Aredia Calcium Metabolism Modifiers Description Intravenous second-generation intravenous bisphosphonateUsed primarily for hypercalcemia of malignancy and to reduce skeletal adverse events in selected cancer patientsFor other indications, more potent bisphosphonates are preferred Indications Indicated for the treatment of hypercalcemia.For the treatment of osteolytic lesions of multiple myeloma or…

  • Etidronate

    Brands Classes DEA Class; Rx Common Brand Names; Didronel Calcium Metabolism Modifiers;  Bisphosphonate Derivatives Description Injectable and oral first-generation bisphosphonate with a lower potency and selectivity vs. newer second- and third-generation bisphosphonatesFor Paget’s disease the drug has largely been replaced by newer bisphosphonates that are easier to use and have greater antiresorptive potency; also indicated…