Tag: Cholinergic Antagonist
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Solifenacin
Brands Classes DEA Class; Rx Common Brand Names; VESIcare, VESIcare LS Anticholinergics, Genitourinary Description Oral competitive selective M3 antimuscarinic agentUsed for overactive bladder (OAB) in adult or pediatric patients 2 years and older; in adults may be used in combination with a beta-3 adrenoreceptor agonistCommon side effects include dry mouth or constipation; monitor for urinary…
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Scopolamine
Brands Classes DEA Class; Rx Common Brand Names; Transderm Scop, Scopace, Maldemar Antiemetic Agents Description Antimuscarinic, mostly used transdermallyPrimarily used for the prevention of motion sickness; may be used for post-operative nausea/vomiting (PONV) or procedural sedationHigh anticholinergic properties Indications For the treatment of nausea/vomiting. For nausea/vomiting prophylaxis due to motion sickness. For use in aspiration…
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Oxybutynin
Brands Classes DEA Class; Rx Common Brand Names; Ditropan XL Antispasmodic Agents, Urinary Description Combination of a short-acting antimuscarinic agent (ipratropium), with a short-acting beta-agonist (SABA, albuterol)Primarily used in the treatment of COPD in adults, also used off-label for acute asthma exacerbation in adult and pediatric patientsAvailable as an oral inhalation or nebulizer solution…
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Albuterol/Ipratropium
Brands Classes DEA Class; Rx Common Brand Names; Combivent Respimat Respiratory Inhalant Combos Description Combination of a short-acting antimuscarinic agent (ipratropium), with a short-acting beta-agonist (SABA, albuterol)Primarily used in the treatment of COPD in adults, also used off-label for acute asthma exacerbation in adult and pediatric patientsAvailable as an oral inhalation or nebulizer solution…
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Ipratropium
Brands Classes DEA Class; Rx Common Brand Names; Atrovent, Atrovent HFA Anticholinergics, Respiratory Description Tertiary amine antimuscarinic; one of the isomers of atropine; used for hypermotility disorders of the lower urinary tract or to control excessive salivary or respiratory secretions. Indications Indicated for Maintenance treatment of bronchospasm, including chronic bronchitis and emphysema For the…
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Methenamine/Hyoscyamine/Methylene Blue/Phenyl Salicylate/Sodium Phosphate Monobasic
Brands Classes DEA Class; Rx Common Brand Names; Uribel, Uticap, Utrona-C, Uretron D/S Antibiotics, Other Description Combination product used to relieve symptoms of urinary irritation or urinary tract infection. Indications Indicated for the treatment of symptoms of irritative voiding including for the relief of local urinary symptoms such as inflammation, hypermotility, and mild pain, which accompany…
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Methenamine/Hyoscyamine (Discontinued)
Discontinued Classes DEA Class; Rx Common Brand Names; Prosed DS, Darpaz, Urogesic Blue Antibiotics, Other Description Methenamine: Hydrolyzed in acidic urine to ammonia and formaldehyde, which are bactericidal agents; does not convert to formaldehyde in serum Hyoscyamine: Elicits anticholinergic activity; decreases urinary spasms with cystitis Additional ingredients in some products: Methylene blue (weak antiseptic properties); sodium…
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Hyoscyamine
Brands Classes DEA Class; Rx Common Brand Names; Levbid, Levsin, Anaspaz, Cystospaz, NuLev, Symax Duotab Anticholinergic Agents Description Tertiary amine antimuscarinic; one of the isomers of atropine; used for hypermotility disorders of the lower urinary tract or to control excessive salivary or respiratory secretions. Indications Indicated for adjunctive treatment of irritable bowel syndrome and neurogenic bladder;…
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Budesonide inhaled/Formoterol/Glycopyrrolate Inhaled
Brands Classes DEA Class; Rx Common Brand Names; Breztri COPD Agents; Respiratory Inhalant Combos; Corticosteroids, Inhalants; Beta2 Agonists Description Budesonide: Anti-inflammatory corticosteroid; has potent glucocorticoid activity and weak mineralocorticoid activity Formoterol: Long-acting selective beta-2 agonist with rapid onset of action; acts locally as bronchodilator; stimulates intracellular adenyl cyclase, which results in increased cyclic adenosine monophosphate…
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Indacaterol/Glycopyrrolate inhaled
Brands Classes DEA Class; Rx Common Brand Names; Utibron Neohaler Anticholinergics, Respiratory; Beta2 Agonists; Respiratory Inhalant Combos; COPD Agents Description Inhaled combination of a long-acting beta-2 adrenergic agonist (LABA), (indacaterol) and a long-acting muscarinic antagonist (LAMA), (glycopyrrolate)Used in adults for the treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysemaNot indicated for…
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Glycopyrrolate inhaled/Formoterol
Brands Classes DEA Class; Rx Common Brand Names; Bevespi Aerosphere Anticholinergics, Respiratory; Beta2 Agonists; Respiratory Inhalant Combos; COPD Agents Description Combination of an inhaled long-acting antimuscarinic agent (LAMA), (glycopyrrolate) with a long-acting beta-2 adrenergic agonist (LABA), (formoterol)Used in adults for the maintenance treatment of COPD, including chronic bronchitis and/or emphysemaNot indicated for the relief…
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Glycopyrrolate
Brands Classes DEA Class; Rx Common Brand Names; Cuvposa, Dartisla ODT, glycopyrronium, Robinul, Robinul Forte, Seebri Neohaler, Lonhala Magnair Anesthetic Premedication Agents; Anticholinergic Agents Respiratory; COPD Agents Description Parenteral, oral, and inhalational antimuscarinic anticholinergic; less CNS penetration than atropine or scopolamineUsed parenterally to reduce GI secretions perioperatively; commonly used orally to reduce severe drooling in patients…
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Fesoterodine
Brands Classes DEA Class; Rx Common Brand Names; Toviaz Anticholinergics, Genitourinary Description Oral competitive selective antimuscarinic (M3); reduces incontinence episodes and urinary urgencyUsed for treatment of overactive bladder (OAB) in adults and for neurogenic detrusor overactivity (NDO) in pediatric patients 6 years of age and older weighing more than 25 kgActive metabolite is the therapeutic…
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Darifenacin
Brands Classes DEA Class; Rx Common Brand Names; Enablex Anticholinergics, Genitourinary Description Oral competitive selective antimuscarinic (M3); reduces incontinence episodes and urinary urgencyUsed for treatment of overactive bladder (OAB) in adults; used as monotherapy or in combination with a beta-3 adrenoreceptor agonist if neededComparable to oxybutynin in efficacy; less dry mouth and CNS side effects…
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Cyclopentolate/Phenylephrine
Brands Classes DEA Class; Rx Common Brand Names; Cyclomydril Cycloplegics/Mydriatics Description Cyclopentolate is an anticholinergic agent that causes loss of accommodation and mydriasis; Phenylephrine is a sympathomimetic agent that causes vasoconstriction and mydriasis.Used to produce mydriasis for ophthalmologic examination.Patients should not drive or participate in hazardous activities while pupils are dilated. Indications For mydriasis induction…