Tag: cholinergic agonist

Brands Classes DEA Class;  Rx Common Brand Names; Evoxac Salivary Stimulants Description Derivative of acetylcholine and thus functions as a cholinergic agonist; used for xerostomia secondary to Sjogren’s syndrome or radiation therapy; being investigated for Alzheimer’s disease. Indications Indicated for xerostomia in patients with Sjogren’s syndrome Contraindications Uncontrolled asthma, conditions in which miosis is undesirable…

Brands Classes DEA Class;  Rx Common Brand Names; Urecholine Cholinergics, Genitourinary   Description Synthetic parasympathomimetic; used for urinary retention; is occasionally used to offset some of the bothersome anticholinergic reactions to tricyclic antidepressants Indications Indicated for treatment of atonic neurogenic bladder or acute postoperative and postpartum non-obstructive urinary retention. For the treatment of gastroesophageal reflux…

Brands Classes DEA Class;  Rx Common Brand Names; Miochol E Miotics, Direct-Acting Description Direct-acting parasympathomimetic ophthalmic agent; naturally-occurring neurohormone that mediates nerve impulse transmission at cholinergic sites. Used intraocularly to produce rapid miosis during ophthalmic surgery. Indications Indicated for miosis induction in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment ocular surgery where…

Brands Classes DEA Class;  Rx Common Brand Names; ATNAA, DuoDote Cholinergic, Toxicity Antidotes Description Parenteral cholinesterase reactivator; antidote to reverse muscle paralysis from organophosphate anticholinesterase poisoning or overdose of drugs used for myasthenia gravis; atropine must be administered concomitantly. Indications Indicated for treatment of poisoning by organophosphorus nerve agents as well as organophosphorus insecticides in…

Brands Classes DEA Class;  Rx Common Brand Names; Protopam, 2PAM Antidote, Pralidoxime Auto Injector Cholinergic, Toxicity Antidotes Description Parenteral cholinesterase reactivator; antidote to reverse muscle paralysis from organophosphate anticholinesterase poisoning or overdose of drugs used for myasthenia gravis; atropine must be administered concomitantly. Indications For use as an antidote to organophosphate insecticide toxicity. For the treatment…

Brands Classes DEA Class;  Rx Common Brand Names; Phospholine Iodide Miotics, Cholinesterase Inhibitors;  Antiglaucoma, Miotics Description Ophthalmic cholinesterase-inhibitor miotic agentUsed in adults to decrease intraocular pressure; used in pediatric patients to diagnose and treat concomitant esotropias with a significant accommodative componentContraindicated in patients with active uveal inflammation, angle-closure glaucoma without iridectomy, or a hypersensitivity to…

Brands Classes DEA Class;  Rx Common Brand Names; Exelon, Exelon Patch Acetylcholinesterase Inhibitors, Central;  Cholinesterase Inhibitors Description Oral and transdermal cholinesterase inhibitorOral and transdermal formulations approved for mild to moderate dementia due to Alzheimer’s or Parkinson’s disease; transdermal patch also approved for severe Alzheimer’s disease; may provide cognitive benefit in dementia with Lewy bodiesRequires slow…

Brands Classes DEA Class;  Rx Common Brand Names; Mestinon, Regonol Acetylcholinesterase Inhibitors, Peripheral Description Oral and parenteral cholinesterase inhibitorUsed for myasthenia gravis and reversal of neuromuscular blocking effects of nondepolarizing muscle relaxants as well as for military medical use as pretreatment for exposure to Soman nerve agentLonger duration of action and associated with fewer muscarinic…

Generic Only Classes DEA Class;  Rx Common Brand Names;  Acetylcholinesterase Inhibitors, Peripheral;  Anticholinergic Toxicity Antidotes      Description Indirect acting parasympathomimetic via inhibition of acetylcholinesterase Indications For the Anticholinergic Toxicity Rarely used; indicated only when life-threatening symptoms related to anticholinergic toxicity Useful for diagnostic as opposed to therapeutic reasons Contraindications Salicylate allergy Asthma, gangrene, diabetes, cardiovascular…

Brands Classes DEA Class;  Rx Common Brand Names; Prostigmin, Bloxiverz Acetylcholinesterase Inhibitors, Central Description Oral, SC, IM, and IV cholinesterase inhibitorUsed for symptomatic tx of myasthenia gravis (PO, SC, IM), reversal of non-depolarizing neuromuscular blocking agents (IV), and for prevention/tx of post-op distention and urinary retention (SC, IM)Similar to, but shorter-acting than, pyridostigmine Indications For…

Brands Classes DEA Class;  Rx Common Brand Names; Razadyne ER Acetylcholinesterase Inhibitors, Central Description Oral cholinesterase inhibitorUsed for the symptomatic treatment of mild to moderate Alzheimer’s disease; may provide cognitive benefit in mixed vascular dementia and Alzheimer’s diseaseA slow dosage titration is required to limit GI side effects Indications Indicated for mild-to-moderate demential of the…

Brands Classes DEA Class;  Rx Common Brand Names; Enlon Plus Antidotes, Systemic Description Combined cholinesterase inhibitor, edrophonium, and antimuscarinic agent, atropineUsed IV to reverse the effects of nondepolarizing neuromuscular blocking agents (e.g., curare type)Edrophonium exerts the primary actions, while atropine decreases the adverse reactions associated with edrophonium Indications For use in nondepolarizing neuromuscular blockade reversal or…

Brands Classes DEA Class;  Rx Common Brand Names; Enlon Myasthenia Gravis Agents Description Parenteral cholinesterase inhibitorUsed for diagnosing myasthenia gravis, assessing cholinesterase inhibitor therapy, differentiating cholinergic and myasthenic crises, and reversing effects of nondepolarizing neuromuscular blockers after surgery; adjunct to atropine for treating respiratory depression associated with curare overdosageDrug of choice for diagnosing myasthenia gravis…

Brands Classes DEA Class;  Rx Common Brand Names; Namzaric Acetylcholinesterase Inhibitors, Central;  NMDA Antagonists Description Combination acetylcholinesterase inhibitor and NMDA receptor antagonistUsed for moderate to severe Alzheimer’s disease stabilized on donepezil and/or memantine separately; adults with mixed vascular dementia and Alzheimer’s disease may experience a small cognitive benefitDonepezil has a known risk of QT prolongation;…

Brands Classes DEA Class;  Rx Common Brand Names; Aricept, Aricept ODT Acetylcholinesterase Inhibitors, Central Description Reversible cholinesterase inhibitor (ChEI); available in oral and transdermal system formulationsApproved for symptom management of mild to severe Alzheimer’s diseasen adults; may provide cognitive benefit in mixed dementia and dementia with Lewy bodiesIn patients with risk factors for QT prolongation…