Tag: Cephalosporins

  • Cephalexin

    Brands Classes DEA Class; Rx Common Brand Names; Keflex, Panixine Disperdose Cephalosporins, 1st Generation Description Oral, first-generation cephalosporin used primarily for otitis media and infections of the respiratory tract due to susceptible staphylococci, Streptococcus pneumoniae, and group A beta-hemolytic streptococci. Indications Indicated for the treatment of upper respiratory tract infections, including group A beta-hemolytic streptococcal…

  • Cefuroxime

    Brands Classes DEA Class; Rx Common Brand Names; Ceftin, Zinacef Cephalosporins, 2nd Generation Description Oral/parenteral second-generation cephalosporinUsed for severe upper and lower respiratory tract infections, skin infections, otitis media, and surgical prophylaxisOral tablets and suspension are not bioequivalent and are not substitutable on a milligram-per-milligram basis Indications Indicated for the treatment of Pharyngitis/Tonsillitis Indicated for…

  • Ceftriaxone

    Brands Classes DEA Class; Rx Common Brand Names; Rocephin (DSC) Cephalosporins, 3rd Generation Description Parenteral third-generation cephalosporin antibioticUsed to treat infections such as gonorrhea, respiratory tract infections, and meningitisHas longest half-life of all cephalosporins, allowing for once-daily dosing and for outpatient therapy Indications Indicated for the treatment of bacteremia and sepsis. For the treatment of…

  • Ceftazidime/Avibactam

    Brands Classes DEA Class; Rx Common Brand Names; Avycaz Cephalosporins, 3rd Generation Description Combination intravenous anti-infective, including a third-generation cephalosporin and beta-lactamase inhibitorFor complicated intra-abdominal infections (with metronidazole), complicated urinary tract infections, and hospital-acquired and ventilator-associated pneumonia (HAP/VAP) in adult and pediatric patients 3 months and olderDecreased efficacy seen in adult patients with complicated intra-abdominal…

  • Ceftazidime

    Brands Classes DEA Class; Rx Common Brand Names; Fortaz, Tazicef, Tazidime Cephalosporins, 3rd Generation Description Parenteral third-generation cephalosporinExtremely active against Pseudomonas aeruginosa; used for lower respiratory tract infections, skin and soft-tissue infections, UTIs, bone and joint infections, and meningitisLimited use for empiric monotherapy for neutropenic fever due to emergence of resistant pathogens and poor gram-positive activity…

  • Ceftaroline

    Brands Classes DEA Class; Rx Common Brand Names; Teflaro Cephalosporins, Other Description IV broad spectrum cephalosporin antibioticUsed for acute bacterial skin and skin structure infections and community-acquired pneumoniaFirst beta-lactam approved to treat methicillin-resistant S. aureus (MRSA), vancomycin-resistant S. aureus (VRSA), vancomycin-insensitive S. aureus (VISA), and hetero-resistant vancomycin-insensitive S. aureus (hVISA) Indications Indicated for treatment of…

  • Cefprozil

    Brands Classes DEA Class; Rx Common Brand Names; Cefzil Cephalosporins, 2nd Generation Description Oral, semisynthetic, second-generation cephalosporin. Clinical uses include otitis media, soft-tissue infections, and respiratory tract infections. Indications Indicated for the treatment of mild to moderate pharyngitis or tonsillitis. For the treatment of acute bacterial exacerbation of chronic bronchitis.For the treatment of otitis media.For…

  • Cefoxitin

    Generic Only Classes DEA Class; Rx Common Brand Names;  Cephalosporins, 2nd Generation Description Second-generation cephalosporin with activity against some gram-positive cocci, gram-negative rod infections, and anaerobic bacteria. Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins; inhibits final transpeptidation step of peptidoglycan synthesis, resulting in cell wall death Indications…

  • Cefotetan

    Generic Only Classes DEA Class; Rx Common Brand Names; Cefotan Cephalosporins, 2nd Generation Description Parenteral second-generation cephalosporinUsed for abdominal and soft-tissue infections, respiratory tract infections, and UTIsLonger half-life allows for twice-daily dosing compared to cefoxitin, which requires usual dosing of 4 times per day Indications Indicated for the treatment of lower respiratory tract infections and…

  • Cefixime

    Brands Classes DEA Class; Rx Common Brand Names; Suprax Cephalosporins, 3rd Generation Description Oral third-generation cephalosporin.Enhanced antibacterial activity and increased stability against many beta-lactamases.Commonly used for otitis media, respiratory tract infections, and UTIs. Indications Indicated in the treatment of acute exacerbations of chronic bronchitis caused by susceptible isolates of Streptococcus pneumoniae and Haemophilus influenzae. Indicated…

  • Cefepime

    Brands Classes DEA Class; Rx Common Brand Names; Maxipime Cephalosporins, Other Description Parenteral fourth-generation cephalosporin. Pharmacokinetics and spectrum of activity similar to ceftazidime. Clinical uses are similar to those of the third-generation cephalosporins. Indications Indicated for Treatment of moderate-to-severe pneumonia. Empiric therapy in febrile neutropenic patients. Treatment of uncomplicated and complicated urinary tract infections (UTIs),…

  • Cefdinir

    Brands Classes DEA Class; Rx Common Brand Names;  Cephalosporins, 3rd Generation Description Oral extended-spectrum, semisynthetic, third generation cephalosporin. It is not active against methicillin-resistant staphylococci or Pseudomonas aeruginosa. Cefdinir is used for skin infections and a variety of upper respiratory infections. Indications Indicated for the treatment of acute otitis media. For the treatment of acute…

  • Cefazolin

    Brands Classes DEA Class; Rx Common Brand Names; Ancef, Kefzol Cephalosporins, 1st Generation Description Parenteral first-generation cephalosporinUsed for respiratory tract, urinary tract, skin and skin structure, biliary tract, bone and joint, and genital infections as well as sepsis, endocarditis, and perioperative prophylaxisGreater activity against gram-positive bacteria than most other cephalosporins, but limited activity against gram-negative…

  • Cefadroxil

    Brands Classes DEA Class; Rx Common Brand Names; Duricef, Ultracef Cephalosporins, 1st Generation Description Oral first-generation cephalosporin. Spectrum includes gram-positive organisms with limited gram-negative coverage. Indicated for UTI, skin and skin structure infections, pharyngitis, and tonsillitis. Indications Indicated for the treatment of urinary tract infection (UTI), including cystitis. For the treatment of skin and skin…

  • Cefaclor

    Brands Classes DEA Class; Rx Common Brand Names; Ceclor (DSC), Raniclor (DSC) Cephalosporins, 2nd Generation Description Oral second-generation cephalosporin used primarily to treat otitis media, sinusitis, and upper respiratory tract infection caused by H. influenzae that are resistant to ampicillin or amoxicillin. Indications Indicated for Lower respiratory tract infections, including pneumonia, caused by Streptococcus pneumoniae,…