DrugsAce

Tag: Cell Wall Inhibitors (Antibiobics)

  • Amoxicillin/​Clavulanic Acid

    Brands Classes Amoxicillin/Clavulanate DEA Class; Rx Common Brand Names; Augmentin, Augmentin XR, Augmentin ES-600 Penicillins, Amino Description Contains amoxicillin and clavulanic acid; clavulanic acid is a beta-lactamase inhibitor that reestablishes amoxicillin’s activity against beta-lactamase-producing bacteria; drug combination has good activity against beta-lactamase producing H. influenzae and penicillinase-producing anaerobes; used commonly for upper respiratory infections, otitis media…

  • Aztreonam

    Brands Classes DEA Class; Rx Common Brand Names; Azactam, Cayston Monobactams Description Synthetic beta-lactam antibiotic; spectrum limited to aerobic gram-negative bacteria; no gram-positive or anaerobic activity; less nephrotoxic than aminoglycosides; not indicated for meningitis. Aztreonam for inhalation indicated for CF patients >= 7 years. Indications Indicated for Systemic Infections, Pseudomonal Infections, Urinary Tract Infections, Cystic…

  • Meropenem/​Vaborbactam

    Brands Classes DEA Class; Rx Common Brand Names; Vabomere Carbapenems Description Combination of meropenem, a carbapenem antibacterial, and vaborbactam, a beta-lactamase inhibitorUsed for complicated urinary tract infections (cUTIs) including pyelonephritis in adults caused by susceptible E. coli, K. pneumoniae, and E. cloacaeActivity against meropenem-resistant organisms, including KPC-producing Enterobacteriaceae Indications Indicated for complicated urinary tract infections…

  • Meropenem

    Brands Classes DEA Class; Rx Common Brand Names; Merrem IV Carbapenems Description IV carbapenem antibioticUsed for complicated intraabdominal and skin and skin structure infections and bacterial meningitisMay have a lower incidence of ADRs than imipenem Indications Indicated as a single agent therapy for the treatment of complicated skin and skin structure infections due to Staphylococcus…

  • Imipenem/Cilastatin/Relebactam

    Brands Classes DEA Class; Rx Common Brand Names; Recarbrio Carbapenems Description Imipenem: Carbapenem; inhibits bacterial cell-wall synthesis by binding to penicillin-binding proteins resulting in bacterial cell lysis Cilastatin: Prevents renal metabolism of imipenem by competing with dehydropeptidase in the renal tubules Relebactam: Has no intrinsic antibacterial activity; protects imipenem from degradation by certain serine beta-lactamases…

  • Imipenem/Cilastatin

    Brands Classes DEA Class; Rx Common Brand Names; Invanz Carbapenems Description Beta-lactam antibiotic derived from thienamycin. Cilastatin added to reduce renal metabolism of imipenem. Without cilastatin, imipenem is rapidly metabolized and causes toxicity to the proximal tubule. Cilastatin has no antibacterial activity. Imipenem is more efficient at penetrating through the bacterial cell wall, resistant to…

  • Ertapenem

    Brands Classes DEA Class; Rx Common Brand Names; Invanz Carbapenems Description IV or IM broad-spectrum carbapenem antibiotic stable against beta-lactamasesUsed to treat UTI, skin, pelvic, intraabdominal infections and community-acquired pneumonia; used for colorectal surgical prophylaxisOnce-daily dosing may be advantageous, but no P. aeruginosa activity  Indications Indicated for the treatment of Community-Acquired Pneumonia Indicated for the…

  • Doripenem

    Brands Classes DEA Class; Rx Common Brand Names; Doribax Carbapenems Description IV broad spectrum carbapenem antibioticFor complicated intraabdominal and urinary tract infections in adultsSpectrum of activity similar to imipenem and meropenem but is more active in vitro against Pseudomonas aeruginosa Indications Indicated for the treatment of complicated intraabdominal infections. For the treatment of complicated urinary…

  • Cephalexin

    Brands Classes DEA Class; Rx Common Brand Names; Keflex, Panixine Disperdose Cephalosporins, 1st Generation Description Oral, first-generation cephalosporin used primarily for otitis media and infections of the respiratory tract due to susceptible staphylococci, Streptococcus pneumoniae, and group A beta-hemolytic streptococci. Indications Indicated for the treatment of upper respiratory tract infections, including group A beta-hemolytic streptococcal…

  • Cefuroxime

    Brands Classes DEA Class; Rx Common Brand Names; Ceftin, Zinacef Cephalosporins, 2nd Generation Description Oral/parenteral second-generation cephalosporinUsed for severe upper and lower respiratory tract infections, skin infections, otitis media, and surgical prophylaxisOral tablets and suspension are not bioequivalent and are not substitutable on a milligram-per-milligram basis Indications Indicated for the treatment of Pharyngitis/Tonsillitis Indicated for…

  • Ceftriaxone

    Brands Classes DEA Class; Rx Common Brand Names; Rocephin (DSC) Cephalosporins, 3rd Generation Description Parenteral third-generation cephalosporin antibioticUsed to treat infections such as gonorrhea, respiratory tract infections, and meningitisHas longest half-life of all cephalosporins, allowing for once-daily dosing and for outpatient therapy Indications Indicated for the treatment of bacteremia and sepsis. For the treatment of…

  • Ceftazidime/Avibactam

    Brands Classes DEA Class; Rx Common Brand Names; Avycaz Cephalosporins, 3rd Generation Description Combination intravenous anti-infective, including a third-generation cephalosporin and beta-lactamase inhibitorFor complicated intra-abdominal infections (with metronidazole), complicated urinary tract infections, and hospital-acquired and ventilator-associated pneumonia (HAP/VAP) in adult and pediatric patients 3 months and olderDecreased efficacy seen in adult patients with complicated intra-abdominal…

  • Ceftazidime

    Brands Classes DEA Class; Rx Common Brand Names; Fortaz, Tazicef, Tazidime Cephalosporins, 3rd Generation Description Parenteral third-generation cephalosporinExtremely active against Pseudomonas aeruginosa; used for lower respiratory tract infections, skin and soft-tissue infections, UTIs, bone and joint infections, and meningitisLimited use for empiric monotherapy for neutropenic fever due to emergence of resistant pathogens and poor gram-positive activity…

  • Ceftaroline

    Brands Classes DEA Class; Rx Common Brand Names; Teflaro Cephalosporins, Other Description IV broad spectrum cephalosporin antibioticUsed for acute bacterial skin and skin structure infections and community-acquired pneumoniaFirst beta-lactam approved to treat methicillin-resistant S. aureus (MRSA), vancomycin-resistant S. aureus (VRSA), vancomycin-insensitive S. aureus (VISA), and hetero-resistant vancomycin-insensitive S. aureus (hVISA) Indications Indicated for treatment of…

  • Cefprozil

    Brands Classes DEA Class; Rx Common Brand Names; Cefzil Cephalosporins, 2nd Generation Description Oral, semisynthetic, second-generation cephalosporin. Clinical uses include otitis media, soft-tissue infections, and respiratory tract infections. Indications Indicated for the treatment of mild to moderate pharyngitis or tonsillitis. For the treatment of acute bacterial exacerbation of chronic bronchitis.For the treatment of otitis media.For…