Tag: Benzodiazepines
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Triazolam
Brands Classes DEA Class; Rx Common Brand Names; Halcion Sedative/Hypnotics Description Short acting benzodiazepine; no active metabolites; anterograde amnesia reported more frequently with triazolam than with other hypnotic benzodiazepines; used for insomnia. Indications Indicated for the short-term treatment of insomnia. Contraindications Documented hypersensitivity Acute alcohol intoxication Myasthenia gravis (allowable in limited circumstances) Narrow angle glaucoma…
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Temazepam
Brands Classes DEA Class; Rx Common Brand Names; Restoril Sedative/Hypnotics Description Oral benzodiazepine; shorter half-life than flurazepam and no active metabolites; for insomnia. Indications Indicated for the short-term treatment of insomnia. Contraindications Documented hypersensitivity Acute alcohol intoxication Narrow-angle glaucoma (questionable) Adverse Effects Drowsiness (9.1%) Dizziness (4.5%) Lethargy (4.5%) Hangover (2.5%) Diarrhea (1.7%) Euphoria (1.5%) Weakness…
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Quazepam
Brands Classes DEA Class; Rx Common Brand Names; Doral Sedative/Hypnotics Description Long-acting oral benzodiazepine with two active metabolites with long half-lives. Used for the short-term treatment of insomnia. May cause excessive daytime drowsiness, rarely associated with rebound insomnia upon discontinuation. Indications Indicated for the treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal…
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Oxazepam
Brands Classes DEA Class; Rx Common Brand Names; Serax Antianxiety Agents; Anxiolytics, Benzodiazepines Description Short-acting oral benzodiazepine metabolized to inactive metabolites; may be a preferred agent in those with hepatic disease; used primarily for anxiety disorders or acute alcohol withdrawal. Indications Indicated for the treatment of anxiety. For treatment of acute alcohol withdrawal.For the treatment…
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Midazolam
Brands Classes DEA Class; Rx Common Brand Names; Seizalam, Versed (DSC), Nayzilam Antianxiety Agents; Anxiolytics, Benzodiazepines; Anticonvulsants, Benzodiazepine Description Oral/parenteral/intranasal short-acting benzodiazepineUsed for sedation, anxiolysis, amnesia, and acutely for seizuresBlack-box warning describing risk of profound sedation and respiratory depression with concomitant opioid use Indications Indicated for procedural sedation and amnesia induction and to control preoperative…
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Lorazepam
Brands Classes DEA Class; Rx Common Brand Names; Ativan, Loreev XR Antianxiety Agents; Anxiolytics, Benzodiazepines; Anticonvulsants, Benzodiazepine Description Oral and parenteral intermediate-acting benzodiazepine with no active metabolitesApproved for anxiety, status epilepticus, perioperative sedation or amnesia induction, and the short-term treatment of insomnia in adults; several off-label usesAvoid coadministration with opioids if possible due to potential…
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Flurazepam
Brands Classes DEA Class; Rx Common Brand Names; Dalmane Sedative/Hypnotics Description Oral benzodiazepine with a relatively long half life.Used as a hypnotic agent in the short-term management of insomnia.Likely to cause residual daytime effects vs. other shorter-acting benzodiazepines. Indications Indicated for the short-term treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings,…
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Diazepam
Brands Classes DEA Class; Rx Common Brand Names; Valium, Diastat, Diastat AcuDial, Valtoco, Antianxiety Agents; Anxiolytics, Benzodiazepines; Skeletal Muscle Relaxants; Anticonvulsants, Benzodiazepine Description Oral, nasal, parenteral, or rectal long-acting benzodiazepineUsed for anxiety, acute alcohol withdrawal, skeletal muscle spasm, and seizure disordersIncreased risk of profound sedation, respiratory depression, coma, and death with concomitant opioid use Indications Indicated…
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Clorazepate
Brands Classes DEA Class; Rx Common Brand Names; Tranxene SD, Tranxene T-Tab Antianxiety Agents; Anxiolytics, Benzodiazepines; Anticonvulsants, Benzodiazepine Description Oral benzodiazepine with a long half-life; essentially a prodrug for desmethyldiazepam, the primary active metabolite of diazepam.Used primarily for partial seizures or anxiety. Indications Indicated for the adjunctive treatment of partial seizures. For the treatment of…
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Estazolam
Brands Classes DEA Class; Rx Common Brand Names; ProSom Sedative/Hypnotics Description Intermediate-acting oral benzodiazepine; no active metabolites.Used for the short-term treatment of insomnia. Indications Indicated for the short-term treatment of insomnia characterized by difficulty in falling asleep, nocturnal awakenings, and/or early morning awakenings. For the treatment of insomnia in adults with generalized anxiety disorder (GAD).…
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Clonazepam
Brands Classes DEA Class; Rx Common Brand Names; Klonopin Antianxiety Agents; Anxiolytics, Benzodiazepines; Anticonvulsants, Benzodiazepine Description Oral long-acting benzodiazepine with no active metabolitesApproved for panic disorder in adults and as prophylaxis of absence, petit mal variant (Lennox-Gastaut syndrome), akinetic, and myoclonic seizures in adult and pediatric patientsAvoid coadministration with opioids if possible due to potential…
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Chlordiazepoxide/Amitriptyline
Brands Classes DEA Class; Rx Common Brand Names; Limbitrol, Limbitrol DS Antidepressants, TCAs; Anxiolytics, Benzodiazepines; Psychotherapeutic Combos Description Oral antidepressant/anti-anxiety combination product.Amitriptyline is a tricyclic antidepressant (TCA), chlordiazepoxide is a benzodiazepine.Common ADRs include anticholinergic effects and drowsiness. Indications Indicated for the treatment of moderate to severe depression with concurrent symptoms of moderate to severe anxiety…
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Chlordiazepoxide
Brands Classes DEA Class; Rx Common Brand Names; Librium Antianxiety Agents; Anxiolytics, Benzodiazepines Description Binds receptors at several sites within the CNS, including the limbic system and reticular formation. Effects may be mediated through the GABA receptor system. Increase in neuronal membrane permeability to chloride ions enhances the inhibitory effects of GABA; the shift in…
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Alprazolam
Brands Classes DEA Class; Rx Common Brand Names; Xanax, Niravam, Xanax XR Antianxiety Agents; Anxiolytics, Benzodiazepine Description Oral intermediate-acting benzodiazepine with minimally active metabolites Approved for panic disorder, generalized anxiety disorder, and short-term treatment of anxiety symptoms in adults; rarely used in pediatric patients off-label Avoid coadministration with opioids if possible due to potential for profound…