Tag: Antiviral

Brands Classes DEA Class; Rx Common Brand Names; Stribild HIV, ART Combos Description Fixed-dose combination tablet containing elvitegravir, an HIV integrase strand transfer inhibitor; cobicistat, a pharmacokinetic enhancer; emtricitabine, a nucleoside reverse transcriptase inhibitor or NRTI; and tenofovir DF, an acyclic nucleotide reverse transcriptase inhibitorUsed for the treatment of HIV-1 infection in patients who are…

Brands Classes DEA Class; Rx Common Brand Names; Atripla  HIV, ART Combos Description Combination of a non-nucleoside, a nucleoside, and a nucleotide reverse transcriptase inhibitorUsed for the treatment of human immunodeficiency virus (HIV) infectionBlack Box Warning for patients coinfected with HIV and hepatitis B Indications Indicated for the treatment of human immunodeficiency virus (HIV) infection.…

Brands Classes DEA Class; Rx Common Brand Names; Complera  HIV, ART Combos Description Combination of 2 NRTIs and 1 NNRTIIndicated as a complete regimen for treatment of HIV-1 infections in antiretroviral-naive adults and pediatric patients (weighing at least 35 kg) with baseline HIV-1 RNA of 100,000 copies/mL or less and certain virologically-stable (HIV-1 RNA less…

Brands Classes DEA Class; Rx Common Brand Names; Truvada  HIV, ART Combos Description Combination product of a nucleotide and a nucleoside reverse transcriptase inhibitorUsed in combination with other antiretroviral agents for the treatment of HIV infection, and in combination with safe sex practices for HIV pre-exposure prophylaxis in adults and adolescents without HIV weighing more…

Brands Classes DEA Class; Rx Common Brand Names; Viread HIV, NRTIs Description Nucleotide reverse transcriptase inhibitorUsed for the treatment of HIV infection and chronic HBV infectionDecreases in bone mineral density reported in patients receiving tenofovir Also available combined with emtricitabine (Truvada), emtricitabine/efavirenz (Atripla), emtricitabine/rilpivirine (Complera) Indications Indicated in combination with other antiretroviral agents for treatment…

Brands Classes DEA Class; Rx Common Brand Names; Genvoya HIV, ART Combos Description Fixed-dose combination tablet containing elvitegravir, an HIV integrase strand transfer inhibitor; cobicistat, a pharmacokinetic enhancer; emtricitabine, a nucleoside reverse transcriptase inhibitor or NRTI; and tenofovir alafenamide, an acyclic nucleotide reverse transcriptase inhibitorUsed for the treatment of HIV-1 infection in adults and pediatric…

Brands Classes DEA Class; Rx Common Brand Names; Symtuza HIV, ART Combos Description Darunavir: Protease inhibitor; selectively inhibits cleavage of Gag-Pol polyprotein precursors, thereby preventing the formation of mature virus particles Cobicistat: CYP3A4 inhibitor; mechanism-based pharmaco-enhancer; first product to be developed and submitted solely as pharmacokinetic booster; enhances the systemic exposure of CYP3A substrates (eg,…

Brands Classes DEA Class; Rx Common Brand Names; Odefsey HIV, ART Combos Description Combination of 2 NRTIs and 1 NNRTIIndicated as a complete regimen for treatment of HIV-1 infections in antiretroviral-naive patients (weighing at least 35 kg) with baseline HIV RNA of 100,000 copies/mL or less, and certain virologically-stable (HIV RNA less than 50 copies/mL)…

Brands Classes DEA Class; Rx Common Brand Names; Biktarvy HIV, ART Combos Description Oral 3-drug combination of an integrase strand inhibitor (bictegravir) and 2 nucleoside analog reverse transcriptase inhibitors (emtricitabine and tenofovir alafenamide)Used as complete regimen for the treatment of HIV-1 infection in adults and pediatric patients weighing 14 kg or moreBlack Box Warning for…

Brands Classes DEA Class; Rx Common Brand Names; Descovy HIV, ART Combos Description Combination product containing 2 nucleoside analog reverse transcriptase inhibitors (NRTIs)Used as part of a combination regimen to treat HIV-1 in adults and pediatric patients who weigh at least 14 kg and in combination with safe sex practices for HIV pre-exposure prophylaxis in…

Brands Classes DEA Class; Rx Common Brand Names; Vemlidy Hepatitis B, NRTIs Description Hepatitis B virus (HBV) nucleoside analog reverse transcriptase inhibitorUsed to treat chronic HBV infection in patients 12 years and older with compensated liver disease; guidelines recommend use with other antiretroviral agents to treat HIVBlack Box Warning for acute HBV exacerbations upon treatment…

Brands Classes DEA Class; Rx Common Brand Names; Pegasys, Pegasys ProClick Hepatitis B/Hepatitis C Agents Description Covalent conjugate of recombinant interferon alfa-2a with PEGUsed to treat chronic HCV infections in patients 5 years and older, and chronic HBV infections in patients 3 years and olderImproved tolerability when compared with interferon alfa-2a Indications Indicated as part…

Brands Classes DEA Class; Rx Common Brand Names; Symfi, Symfi Lo HIV, ART Combos Description Tenofovir: NRTI; following hydrolysis and phosphorylation, inhibits HIV-1 reverse transcriptase by competing with AMP as substrate Lamivudine: NRTI; following phosphorylation, inhibits HIV reverse transcriptase by viral DNA chain termination; cytosine analog Efavirenz: NNRTI; activity against HIV-1 by binding to reverse…

Brands Classes DEA Class; Rx Common Brand Names; Cimduo, Temixys HIV, ART Combos Description Oral 2-drug combination of a nucleoside reverse transcriptase inhibitor and an acyclic nucleoside analog (i.e., nucleotide reverse transcriptase inhibitor)Used with other antiretroviral drugs to treat HIV-1 in adult and pediatric patients weighing at least 35 kgBlack Box Warning for patients coinfected…