DrugsAce

Tag: Antiviral

  • Trifluridine

    Brands Classes DEA Class; Rx Common Brand Names; Viroptic (DSC) Antivirals, Ophthalmic Description Ophthalmic antiviral preparation with activity against herpes simplex virus (HSV) types 1 and 2, vaccinia virus, and some adenovirus strains; used for primary keratoconjunctivitis and recurrent epithelial keratitis due HSV types 1 and 2; used for epithelial keratitis that has not responded…

  • Penciclovir

    Brands Classes DEA Class; Rx Common Brand Names; Denavir Antivirals, Topical Description Topical antiviral medication; active metabolite of famciclovirFor treatment of herpes labialis in patients 12 years and olderMore favorable results than with topical acyclovir Indications Indicated for the treatment of recurrent herpes labialis. Contraindications Hypersensitivity Adverse Effects Milde erythema Application site reaction (1%) Headache…

  • Ganciclovir

    Brands Classes DEA Class; Rx Common Brand Names; Cytovene, Vitrasert DSC, Zirgan Antivirals, CMV;  Ophthalmic Description Synthetic purine nucleoside analog antiviralUsed for prevention and treatment of CMV; ophthalmic gel approved for acute herpetic keratitisDose adjustment may be required for hematological toxicity (neutropenia, thrombocytopenia) Indications Indicated for the treatment of cytomegalovirus (CMV) retinitis in immunocompromised adults,…

  • Foscarnet

    Brands Classes DEA Class; Rx Common Brand Names; Foscavir, Phosphonoformic acid Antivirals, CMV;  Antivirals, Other Description Antiviral agent; organic analog of inorganic pyrophosphate; not associated with myelosuppression; does not require phosphorylation for activation; used in CMV, herpes simplex, and varicella-zoster. Indications Patients with AIDS: Combination therapy with ganciclovir indated for patients who have relapsed following…

  • Famciclovir

    Brands Classes DEA Class; Rx Common Brand Names; Famvir Antivirals, Other Description Oral antiviral agent; prodrug for penciclovirIndicated for tx of acute herpes zoster, tx or suppression of recurrent genital herpes in immunocompetent patients, acute tx of recurrent herpes labialis in immunocompetent patients, and tx of recurrent mucocutaneous herpes simplex infection in HIV patientsSimilar spectrum…

  • Cidofovir

    Brands Classes DEA Class; Rx Common Brand Names; Vistide (DSC) Antivirals, CMV Description Antiviral; acyclic phosphonate nucleotide analog; structurally similar to acyclovir; not dependent upon intracellular activationUsed for the treatment of cytomegalovirus (CMV), herpes virus infections, and adenovirus infectionsAssociated with renal toxicity; use with probenecid and IV hydration to reduce toxicity Indications Indicated for the…

  • Acyclovir

    Brands Classes DEA Class; Rx Common Brand Names; Zovirax, Avaclyr, Zovirax topical, Sitavig Antivirals, Other;  Antivirals, HSV;  Antivirals, VZV Description Synthetic antiviral with activity against herpes simplex virus type 1 and 2 and varicella-zoster virusUsed to treat herpes labialis, herpes genitalis, herpes simplex encephalitis, herpes simplex keratitis, neonatal herpes infection, chickenpox (varicella), shingles (zoster)Potent activity…

  • Sofosbuvir/Velpatasvir/Voxilaprevir

    Brands Classes DEA Class; Rx Common Brand Names; Vosevi HCV NS5A Inhibitors;  HCV Polymerase Inhibitors;  HCV Protease Inhibitors Description Combination oral antiviralUsed for the treatment of chronic hepatitis C infection in treatment-experienced adults without cirrhosis or with compensated cirrhosis (Child-Pugh A)Risk of hepatitis B virus (HBV) reactivation has been reported in some cases resulting in…

  • Sofosbuvir/​Velpatasvir

    Brands Classes DEA Class; Rx Common Brand Names; Epclusa HCV NS5A Inhibitors;  HCV Polymerase Inhibitors Description Combination oral productUsed to treat adults and pediatric patients 3 years and older infected with chronic hepatitis C virus (HCV), with and without cirrhosisFirst regimen approved for all HCV genotypes Indications Indicated for chronic hepatitis C virus (HCV) infection…

  • Sofosbuvir

    Brands Classes DEA Class; Rx Common Brand Names; Sovaldi Hepatitis B/Hepatitis C Agents;  HCV Polymerase Inhibitors Description Hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitorFor chronic hepatitis C infection, genotypes 1, 2, 3, and 4, in adult patients and genotypes 2 and 3 in pediatric patients 3 years and older, including those with hepatocellular…

  • Ombitasvir/Paritaprevir/Ritonavir

    Brands Classes DEA Class; Rx Common Brand Names; Technivie NS3/4A Protease Inhibitor Antivirals in Combination with NS5A Protein Inhibitor Antivirals for Hepatitis C Description 3 drug oral combination product including a HCV NS5A inhibitor, a NS3/4A protease inhibitor, and a pharmacokinetic enhancerFor use with ribavirin in the treatment of genotype 4 hepatitis C virus (HCV)…

  • Ombitasvir/Paritaprevir/Ritonavir & Dasabuvir (DSC)

    Discontinued Classes DEA Class; Rx Common Brand Names; Viekira Pak (DSC) HCV NS5A Inhibitors;  HCV Polymerase Inhibitors;  HCV Protease Inhibitors Description Combination oral product containing 3 antivirals with activity against HCV and a pharmacokinetic enhancerFor HCV genotype 1a and 1b, including patients with and without compensated cirrhosisContraindicated in patients with moderate to severe hepatic disease…

  • Ledipasvir/​Sofosbuvir

    Brands Classes DEA Class; Rx Common Brand Names; Harvoni HCV NS5A Inhibitors;  HCV Polymerase Inhibitors Description Combination antiviral containing a hepatitis C virus (HCV) NS5A protein inhibitor and a nucleotide analog HCV NS5B polymerase inhibitorUsed to treat chronic HCV genotype 1, 4, 5, and 6 infections in adults and pediatric patients 3 years and olderBlack…

  • Glecaprevir/​Pibrentasvir

    Brands Classes DEA Class; Rx Common Brand Names; Mavyret HCV NS5A Inhibitors;  HCV NS3/4A Protease Inhibitors Description Combination oral antiviral containing an HCV NS3/4A protease inhibitor and NS5A inhibitorFor the treatment of chronic HCV infections (all genotypes) in adults and pediatric patients 3 years and older without cirrhosis or with compensated cirrhosis (Child-Pugh A)Contraindicated in…

  • Elbasvir/Grazoprevir

    Brands Classes DEA Class; Rx Common Brand Names; Zepatier HCV NS5A Inhibitors;  HCV NS3/4A Protease Inhibitors Description Combination product containing an NS5A inhibitor (elbasvir) and an NS3/4A protease inhibitor (grazoprevir)Used to treat adults and pediatric patients weighing at least 30 kg with HCV genotypes 1 and 4 infectionsContraindicated in patients with moderate to severe hepatic…