Tag: Antiviral

Brands Classes DEA Class; Rx Common Brand Names; Isentress, Isentress HD HIV, Integrase Inhibitors Description First FDA-approved HIV integrase strand transfer inhibitor (HIV-1 INSTI)Used for treatment of HIV-1 infection in combination with other antiretroviralsElevated CPK, muscle weakness, and rhabdomyolysis reported Indications Indicated in combination with other antiretroviral agents for HIV-1 infection For the treatment of…

Brands Classes DEA Class; Rx Common Brand Names; Tivicay, Tivicay PD HIV, Integrase Inhibitors Description HIV integrase strand transfer inhibitor (INSTI)Used as part of a combination regimen to treat HIV infection in INSTI-naive adults and pediatric patients 4 weeks and older weighing at least 3 kg; also approved for INSTI-experienced adults with certain resistance profiles;…

Brands Classes DEA Class; Rx Common Brand Names; Selzentry HIV, CRAs Description Entry inhibitorUsed for treatment of CCR5-tropic human immunodeficiency virus (HIV) infection in combination with other antiretroviral agentsTropism assay of the HIV strain required prior to treatment Indications Indicated in combination with other antiretroviral agents for treatment of only CCR5-tropic human immunodeficiency virus type…

Brands Classes DEA Class; Rx Common Brand Names; Fuzeon  HIV, Fusion Inhibitors Description Fusion inhibitorFor use with other antiretroviral agents to treat antiretroviral-experienced patients with evidence of ongoing viral replication98% of patients develop injection site reactions Indications Indicated for the treatment of advanced human immunodeficiency virus (HIV) infection in combination with other antiretroviral agents in…

Brands Classes DEA Class; Rx Common Brand Names; Aptivus HIV, Protease Inhibitors Description Non-peptidic protease inhibitor (PI); must be “boosted” with ritonavirUsed to treat HIV-1 infection in treatment-experienced patients with strains resistant to more than 1 PIBlack Box Warnings regarding fatal and non-fatal hepatotoxicity and intracranial hemorrhage Indications Indicated for the treatment of human immunodeficiency…

Brands Classes DEA Class; Rx Common Brand Names; Invirase HIV, Protease Inhibitors Description Protease inhibitor (PI)Used to treat HIV-1 infections in combination with ritonavir and other antiretroviral agentsOnly use when ‘boosted’ with ritonavir; PR and QT prolongation (including TdP) reported Indications Indicated for the treatment of human immunodeficiency virus (HIV) infection in combination with other…

Brands Classes DEA Class; Rx Common Brand Names; Viracept HIV, Protease Inhibitors Description Protease inhibitorUsed for the treatment of HIV-1 infection in combination with other antiretroviral agentsAvoid use of powder formulation in patients with phenylketonuria Indications Indicated for the treatment of human immunodeficiency virus (HIV) infection in combination with other antiretroviral agents.   Contraindications Hypersensitivity…

Brands Classes DEA Class; Rx Common Brand Names; Kaletra HIV, Protease Inhibitors Description A protease inhibitor (PI)Indicated to treat HIV-1 infection when used in combination with other antiretroviral agentsAvailable as an oral solution and as full-strength and half-strength tablets Indications Indicated for the treatment of human immunodeficiency virus (HIV) infection in combination with other antiretroviral…

Brands Classes DEA Class; Rx Common Brand Names; Crixivan Antiretroviral Agents;  HIV, Protease Inhibitors Description Protease inhibitor (PI)Indicated to treat HIV infection in combination with other antiretroviralsPotential for nephrolithiasis Indications Indicated for the treatment of human immunodeficiency virus (HIV) infection in combination with other antiretroviral agents. Contraindications Hypersensitivity Drugs that are contraindicated with indinavir include…

Brands Classes DEA Class; Rx Common Brand Names; Lexiva HIV, Protease Inhibitors Description Protease inhibitor (PI)For the treatment of human immunodeficiency virus (HIV) infection in combination with other antiretroviral agentsProdrug of amprenavir; improved solubility compared to amprenavir allows for reduced pill burden Indications Indicated for the treatment of human immunodeficiency virus (HIV) infection in combination…

Brands Classes DEA Class; Rx Common Brand Names; Prezcobix HIV, ART Combos Description Fixed-dose combination product containing a protease inhibitor and a pharmacokinetic enhancerUsed with other antiretrovirals to treat HIV-1 infection in treatment-naive and experienced adults and pediatric patients weighing 40 kg or more without darunavir resistance-associated substitutionsGenotypic testing is recommended prior to initiating treatment…

Brands Classes DEA Class; Rx Common Brand Names; Prezista HIV, Protease Inhibitors Description Protease inhibitor (PI)For human immunodeficiency virus (HIV) infection when used in combination with other antiretroviral agentsHIV strains resistant to other PIs are responsive to darunavir Indications Coadministered with ritonavir and in combination with other antiretroviral agents for HIV infection Treatment-naive or antiretroviral…

Brands Classes DEA Class; Rx Common Brand Names; Evotaz HIV, ART Combos Description Fixed-dose combination product containing a protease inhibitor (PI) and a pharmacokinetic enhancerUsed with other antiretrovirals to treat HIV-1 infection in treatment-naive and experienced adults and pediatric patients weighing 35 kg or moreUse in treatment-experienced patients should be guided by the number of…