Tag: Antitubercular Agents (Antibiobics)

Brands Classes DEA Class; Rx Common Brand Names; Rifadin, Rimactane Antitubercular Agents Description Semisynthetic rifamycin antibioticPrimarily used as part of first-line, combination therapy for the treatment of tuberculosis and also used to treat asymptomatic carriers of Neisseria meningitidisPotent inducer of hepatic microsomal enzymes and associated with many significant drug interactions Indications Indicated for Tuberculosis.Indicated for…

Brands Classes DEA Class; Rx Common Brand Names; Trecator Antitubercular Agents Description Second-line agent for tuberculosis; for disease resistant to rifampin and/or isoniazid, or for patients who are intolerant of rifampin and isoniazid; used in combination with at least one other antitubercular drug; only film-coated tablets (Trecator®) available. Indications Indicated for the treatment of drug-susceptible…

Brands Classes DEA Class; Rx Common Brand Names; Capastat Antitubercular Agents Description Bacteriostatic or bactericidal Inhibits cell wall synthesis Indications Indicated for treatment of Tuberculosis Contraindications Hypersensitivity Alcohol use Renal dysfunction, severe History of seizure disorder, mental depression, severe anxiety or psychosis Adverse Effects Confusion Restlessness Drowsiness Vertigo Cardiac arrhythmia Folate deficiency Hyperreflexia Dysarthria Dizziness…

Brands Classes DEA Class; Rx Common Brand Names; Capastat Antitubercular Agents Description Parenteral polypeptide antibiotic, exact mechanism unknown.Used as a second line agent in combination with other medications for the treatment of pulmonary tuberculosis.Practical use is limited by routes of administration, adverse effects of nephrotoxicity and neurotoxicity. Indications Indicated for treatment of Tuberculosis Contraindications Hypersensitivity…

Brands Classes DEA Class; Rx Common Brand Names; Paser 5-Aminosalicylic Acid Derivatives;  Antitubercular Agents Description Oral antituberculosis agent that may inhibit folic acid synthesis and/or inhibit synthesis of a cell wall component Use second-line to treat tuberculosis infection; often used for multi-drug resistant tuberculosisMust be used as part of a multi-drug treatment regimen Indications Indicated for…

Brands Classes DEA Class; Rx Common Brand Names; Sirturo Antitubercular Agents Description Diarylquinoline antimycobacterialFor use in combination with other drugs to treat adults and pediatric patients 5 years and older weighing at least 15 kg with pulmonary multi-drug resistant tuberculosis (MDR-TB) for which no other effective treatment regimens are availableAssociated with an increased risk of…

Brands Classes DEA Class; Rx Common Brand Names; Priftin Antitubercular Agents Description Oral cyclopentyl rifamycin antimycobacterial drugUsed for treatment of active pulmonary tuberculosis (TB) in combination with 1 or more anti-TB drugs and treatment of latent TB infection in patients at high risk of progression to TB diseaseHepatotoxicity and drug-drug interactions may limit use Indications…

Brands Classes DEA Class; Rx Common Brand Names; Rifadin, Rimactane Antitubercular Agents Description Semisynthetic rifamycin antibioticPrimarily used as part of first-line, combination therapy for the treatment of tuberculosis and also used to treat asymptomatic carriers of Neisseria meningitidisPotent inducer of hepatic microsomal enzymes and associated with many significant drug interactions Indications Indicated for Tuberculosis.Indicated for…

Brands Classes DEA Class; Rx Common Brand Names; Mycobutin Antitubercular Agents Description Antimycobacterial agent; alternative to clarithromycin or azithromycin for MAC prophylaxis; alternative to rifampin for TB prophylaxis or treatment. Indications Indicated for prevention of disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infectionOrphan designation for treatment of disseminated Mycobacterium avium complex…

Generic Only Classes DEA Class; Rx Common Brand Names; Nydrazid Antitubercular Agents Description Antituberculosis agent; useful when resistance to isoniazid or rifampin has been confirmed; used in combination with other agents. Indications Indicated for the treatment of drug-susceptible tuberculosis infection as part of combination therapy.For the treatment of drug-resistant tuberculosis infection as part of combination…

Discontinued Classes DEA Class; Rx Common Brand Names; Rifater (DSC) Antitubercular Agents Description Oral combination antitubercular agentUsed to treat the initial phase of pulmonary tuberculosis in patients already receiving a fixed dosage regimen; simplified regimen may promote adherenceMonitor liver enzymes due to potential fatal hepatitis and hepatic dysfunction Indications Indicated in the initial phase of…

Discontinued Classes DEA Class; Rx Common Brand Names; Rifamate (DSC) Antitubercular Agents Description Oral combination antitubercular agentUsed to treat pulmonary tuberculosis in patients already receiving a fixed dosage regimen; simplified regimen may promote adherenceMonitor liver enzymes due to potential fatal hepatitis and hepatic dysfunction Indications Indicated for pulmonary tuberculosis in which organisms are susceptible, and…

Brands Classes DEA Class; Rx Common Brand Names; Nydrazid Antitubercular Agents Description Antimycobacterial agent; considered a first-line agent in the treatment of susceptible M. tuberculosis organisms. Appears to be more effective and less toxic than other antitubercular agents. Indications Indicated for the treatment of Latent Tuberculosis Infection and Active Tuberculosis Disease. Other Indications & Uses…

Brands Classes DEA Class; Rx Common Brand Names; Myambutol Antitubercular Agents Description Used for mycobacterial infections including tuberculosis and atypical mycobacterial infections. First-line antituberculosis agent in combination with isoniazid, pyrazinamide, rifampin, and/or streptomycin. Appears to be more effective and less toxic than other antitubercular agents. Indications Indicated for the treatment of drug-susceptible tuberculosis infection as…