Tag: Antipsychotics
-
Trifluoperazine
Brands Classes DEA Class; Rx Common Brand Names; Stelazine Antipsychotics, 1st Generation Antipsychotics, Phenothiazine Description Oral and parenteral piperazine phenothiazine antipsychotic; similar to fluphenazineUsed primarily as an antipsychoticBoxed warning regarding an increased risk of death in elderly patients with dementia Indications Indicated for the treatment of schizophrenia. For the short-term treatment of non-psychotic generalized…
-
Thiothixene
Brands Classes DEA Class; Rx Common Brand Names; Navane Antipsychotics, 1st Generation Description Antipsychotic drug structurally similar to phenothiazines; 5 mg PO equivalent to 100 mg chlorpromazine; increased risk of death in elderly patients treated for dementia-related psychosis. Indications Indicated for the treatment of schizophrenia. For the treatment of severe behavioral or psychological symptoms of…
-
Prochlorperazine
Brands Classes DEA Class; Rx Common Brand Names; Compazine, Compazine Spansules, prochlorperazine edisylate, prochlorperazine mesylate Antiemetic Agents; Antipsychotics, Phenothiazine Description Oral, rectal, and parenteral phenothiazine used as an antiemetic and antipsychotic agentUsed primarily for nausea and vomitingShares many of the effects of phenothiazine antipsychotics; increased risk of death in elderly patients with dementia Indications Indicated for…
-
Pimozide
Brands Classes DEA Class; Rx Common Brand Names; Orap Antipsychotics, 1st Generation; Description High potency oral antipsychotic; associated with QT prolongation and cardiac arrhythmias; many contraindicated drug interactionsReserved for use for motor and phonic tics of Tourette’s syndrome refractory to standard treatmentAs with all antipsychotics, increased mortality risk in elderly patients treated for dementia-related psychosis…
-
Amitriptyline/Perphenazine
Brands Classes DEA Class; Rx Common Brand Names; Etrafon, Etrafon-A, Triavil Psychotherapeutic Combos Description Oral combination phenothiazine antipsychotic and tricyclic antidepressantUsed for schizophrenia and for moderate to severe anxiety/agitation and associated depressive symptomsBoxed warning for increased risk of suicidality in children, adolescents, and young adults during early treatment phase and increased mortality risk in elderly…
-
Perphenazine
Brands Classes DEA Class; Rx Common Brand Names; Trilafon Antipsychotics, 1st Generation; Antipsychotics, Phenothiazine Description Oral piperazine phenothiazine antipsychotic agentUsed primarily as an antipsychotic agentBoxed warning regarding increased risk of death in elderly patients with dementia Indications Indicated for the treatment of schizophrenia For the treatment of severe nausea/vomiting.For the treatment of severe behavioral or…
-
Molindone
Brands Classes DEA Class; Rx Common Brand Names; Moban Antipsychotics, 1st Generation; Description Oral conventional non-phenothiazine antipsychoticUsed for the treatment of schizophreniaHigh extrapyramidal effects, low sedative effects, and low anticholinergic effects Indications Indicated for the treatment of schizophrenia For the treatment of severe behavioral or psychological symptoms of dementia (BPSD). Contraindications Documented hypersensitivity Severe CNS…
-
Loxapine
Brands Classes DEA Class; Rx Common Brand Names; Loxitane, Adasuve Antipsychotics, 1st Generation; Description Conventional non-phenothiazine antipsychoticOral formulation approved for the treatment of schizophreniaInhalational formulation approved for treating agitation associated with schizophrenia or bipolar I disorderInhalational loxapine is only available through a REMS program due to the risk of bronchospasm, which may result in respiratory…
-
Haloperidol
Brands Classes DEA Class; Rx Common Brand Names; Haldol, Haldol Decanoate, Haloperidol LA, Peridol Antipsychotics, 1st Generation; Description High-potency oral and parenteral conventional antipsychotic structurally related to droperidolOral formulation and immediate-release intramuscular injection FDA-approved for treating schizophrenia and Tourette’s Disorder; immediate-release IM formulation is effective for acute agitation in hospitalized settingsAn intramuscular depot injection is available…
-
Fluphenazine
Brands Classes DEA Class; Rx Common Brand Names; Modecate, Modecate Concentrate, Moditen, Prolixin, RhoFluphenazine Antipsychotics, 1st Generation; Antipsychotics, Phenothiazine Description Piperazine phenothiazine antipsychotic; 2 mg orally equivalent to 100 mg of oral chlorpromazine, the prototype antipsychotic; depot IM injections (i.e., fluphenazine decanoate or fluphenazine enanthate) available for chronic disorders; increased risk of death in elderly patients…
-
Thioridazine
Brands Classes DEA Class; Rx Common Brand Names; Mellaril Antipsychotics, Phenothiazine Description Oral low potency phenothiazine antipsychoticRisk of QT prolongation and torsade de pointes (TdP) limits use to refractory schizophrenic patientsAs with all antipsychotics, boxed warning for increased mortality risk in elderly patients with dementia-related psychosis Indications Indicated for the treatment of schizophrenia in patients…
-
Chlorpromazine
Brands Classes DEA Class; Rx Common Brand Names; Thorazine Antipsychotics, Phenothiazine Description Oral and parenteral phenothiazine antipsychotic; potencies of other antipsychotics are compared to oral chlorpromazine 100 mgPrimarily used as an antipsychotic; occastionally used for presurgical anxiolytic, as an antiemetic, and for treatment of intractable hiccupsBoxed warning regarding an increased risk of death in elderly…