DrugsAce

Tag: Antimicrobial Drugs

  • Rifampin/Isoniazid/Pyrazinamide

    Discontinued Classes DEA Class; Rx Common Brand Names; Rifater (DSC) Antitubercular Agents Description Oral combination antitubercular agentUsed to treat the initial phase of pulmonary tuberculosis in patients already receiving a fixed dosage regimen; simplified regimen may promote adherenceMonitor liver enzymes due to potential fatal hepatitis and hepatic dysfunction Indications Indicated in the initial phase of…

  • Rifampin/Isoniazid

    Discontinued Classes DEA Class; Rx Common Brand Names; Rifamate (DSC) Antitubercular Agents Description Oral combination antitubercular agentUsed to treat pulmonary tuberculosis in patients already receiving a fixed dosage regimen; simplified regimen may promote adherenceMonitor liver enzymes due to potential fatal hepatitis and hepatic dysfunction Indications Indicated for pulmonary tuberculosis in which organisms are susceptible, and…

  • Isoniazid

    Brands Classes DEA Class; Rx Common Brand Names; Nydrazid Antitubercular Agents Description Antimycobacterial agent; considered a first-line agent in the treatment of susceptible M. tuberculosis organisms. Appears to be more effective and less toxic than other antitubercular agents. Indications Indicated for the treatment of Latent Tuberculosis Infection and Active Tuberculosis Disease. Other Indications & Uses…

  • Ethambutol

    Brands Classes DEA Class; Rx Common Brand Names; Myambutol Antitubercular Agents Description Used for mycobacterial infections including tuberculosis and atypical mycobacterial infections. First-line antituberculosis agent in combination with isoniazid, pyrazinamide, rifampin, and/or streptomycin. Appears to be more effective and less toxic than other antitubercular agents. Indications Indicated for the treatment of drug-susceptible tuberculosis infection as…

  • Nitrofurantoin

    Brands Classes DEA Class; Rx Common Brand Names; Macrobid, Macrodantin, Furadantin Antibiotics, Other Description Oral nitrofuran antibacterial agent specifically used to treat urinary tract infections caused by many gram-negative and some gram-positive bacteria. Indications Urinary Tract Infection Susceptible strains of Escherichia coli, Enterobacter spp, Klebsiella spp, Staphylococcus aureus, and S saprophyticus Contraindications Renal failure (anuria, oliguria,…

  • Methenamine/Sodium Acid Phosphate

    Brands Classes DEA Class; Rx Common Brand Names; Uroquid-Acid No. 2, Utac Antibiotics, Other Description Methenamine: Hydrolyzed in acidic urine to ammonia and formaldehyde, which are bactericidal agents; does not convert to formaldehyde in serum Sodium acid phosphate: Urinary acidifier; elicits osmotic effect in GI tract Indications Use only after eradication of UTI by other…

  • Methenamine/Sodium Salicylate/Benzoic Acid

    Brands Classes DEA Class; OTC Common Brand Names; Cystex Antibiotics, Other Description Methenamine: Hydrolyzed in acidic urine to ammonia and formaldehyde, which are bactericidal agents; does not convert to formaldehyde in serum. Sodium salicylate: Analgesic Benzoic acid: Elicits weak antifungal and antibacterial properties; also helps acidify urine Indications Use only after eradication of UTI by…

  • Methenamine

    Brands Classes DEA Class; Rx Common Brand Names; Hiprex, Urex Antibiotics, Other Description Urinary antiinfectiveUsed for suppression and prophylaxis of frequently recurring urinary tract infectionsContraindicated in patients with renal insufficiency, severe hepatic insufficiency, and severe dehydration Indications Indicated for prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary…

  • Cotrimoxazole

    Brands Classes Trimethoprim/Sulfamethoxazole DEA Class; Rx Common Brand Names; Bactrim, Bactrim DS, Septra, Septra DS, Cotrim, cotrimoxazole, Sulfatrim Sulfonamides;  Antibiotics, Combos Description Combination product of trimethoprim and sulfamethoxazole in a fixed 1:5 ratio; both are synthetic folate antagonists. Indications Indicated for acute exacerbations of chronic bronchitis due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae…

  • Trimethoprim/Sulfamethoxazole

    Brands Classes DEA Class; Rx Common Brand Names; Bactrim, Bactrim DS, Septra, Septra DS, Cotrim, cotrimoxazole, Sulfatrim Sulfonamides;  Antibiotics, Combos Description Combination product of trimethoprim and sulfamethoxazole in a fixed 1:5 ratio; both are synthetic folate antagonists. Indications Indicated for acute exacerbations of chronic bronchitis due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae Documented…

  • Trimethoprim

    Brands Classes DEA Class; Rx Common Brand Names; Primsol, Proloprim, TMP  Antibiotics, Other Description Synthetic antifolate-type antiinfective agent. Has activity against gram-positive and gram-negative bacteria. Commonly used for UTI, prophylaxis of UTI, traveler’s diarrhea, and in combination with sulfamethoxazole or dapsone for prophylaxis and treatment of Pneumocystis infections. Indications Indicated for the treatment of acute otitis…

  • Pyrimethamine

    Brands Classes DEA Class; Rx Common Brand Names; Daraprim Antimalarials;  Antiparasitic Agents Description Synthetic antiparasitic agent with slow schizonticidal activityUsed for the treatment of toxoplasmosis in combination with sulfadoxineOnly available through the DARAPRIM Direct Program Indications Indicated for Toxoplasmosis P jiroveci Pneumonia (Off-label) Prophylaxis p P jiroveci pneumonia (formerly Pneumocystis pneumonia); administer with dapsone Treatment…

  • Sulfasalazine

    Brands Classes DEA Class; Rx Common Brand Names; Azulfidine, Azulfidine EN 5-Aminosalicylic Acid Derivatives;  DMARDs, Other Description Oral prodrug; metabolized by intestinal bacteria to sulfapyridine and 5-aminosalicylate (5-ASA, also known as mesalamine)Used to treat ulcerative colitis, rheumatoid arthritis, and juvenille idiopathic arthritis (JIA)The sulfapyridine component is particularly associated with adverse reactions vs. 5-ASA use alone…

  • Sulfadiazine

    Generic Only Classes DEA Class; Rx Common Brand Names;  Sulfonamides Description Exerts bacteriostatic action through competitive antagonism with para-aminobenzoic acid (PABA). Microorganisms that require exogenous folic acid and do not synthesize folic acid are not susceptible to the action of sulfonamides Indications Indicated for Prophylaxis of Recurrent Rheumatic Fever Asymptomatic meningococcal  Other Indications & Uses…

  • Silver Sulfadiazine

    Brands Classes DEA Class; Rx Common Brand Names; Silvadene, Thermazene, SSD Cream Antibacterials, Topical Description Topical sulfonamide antiinfective; wide spectrum of activity against Candida and gram-positive and gram-negative bacteria; used to prevent and treat serious burn and wound infections. Indications Indicated for wound management including the treatment of burn wound infection and burn wound infection prophylaxis…