DrugsAce

Tag: Antimicrobial Drugs

  • Metronidazole/Tetracycline/Bismuth Subsalicylate

    Brands Classes DEA Class; Rx Common Brand Names;  H pylori Agents Description Metronidazole, tetracycline: Inhibits nucleic acid synthesis by disrupting DNA Bismuth Subsalicylate: Antisecretory effect by salicylate, antimicrobial action by bismuth Tetracycline: Binds to the 30S and possibly 50S ribosomal subunits of susceptbible bacteria to inhibit proteain synthesis Indications Indicated for eradication of H pylori…

  • Metronidazole

    Brands Classes DEA Class; Rx Common Brand Names; Flagyl, Flagyl ER, Flagyl IV RTU Nitroimidazoles metronidazole topical (Rx) Brand and Other Names: MetroCream, MetroGel, MetroLotion, Noritate Classes: Antibacterials, Topical metronidazole vaginal (Rx) Brand and Other Names: MetroGel Vaginal, Vandazole, Nuvessa Classes: Antibiotics, Other;  Vaginal Preparations, Other Description Oral/parenteral/topical/vaginal synthetic nitroimidazole; antibacterial and antiprotozoalUsed for anaerobic bacterial infections and protozoal infections such as…

  • Bismuth Subsalicylate

    Brands Classes DEA Class; OTC Common Brand Names; Kaopectate, Pepto Bismol, Maalox Total Relief, Kaopectate Extra Strength, Pepto-Bismol Maximum Strength Antidiarrheals;  H pylori Agents Description Antimicrobial anti-inflammatory action (bismuth); antisecretory effect (salicylate) Indications Indicated for Diarrhea, Gas, Upset Stomach, Indigestion, Heartburn, Nausea, Traveler’s Diarrhea, Helicobacter Pylori Contraindications Hypersensitivity to bismuth, aspirin, other salicylates Infectious diarrhea, high…

  • Rifampicin

    Brands Classes DEA Class; Rx Common Brand Names; Rifadin, Rimactane Antitubercular Agents Description Semisynthetic rifamycin antibioticPrimarily used as part of first-line, combination therapy for the treatment of tuberculosis and also used to treat asymptomatic carriers of Neisseria meningitidisPotent inducer of hepatic microsomal enzymes and associated with many significant drug interactions Indications Indicated for Tuberculosis.Indicated for…

  • Dapsone

    Brands Classes DEA Class; Rx Common Brand Names; Aczone Antileprosy Agents,  Acne Agents, Topical Description Synthetic sulfone chemically similar to sulfonamidesHas antiinfective and immunosuppressive propertiesAgent of choice for all forms of leprosy; used for PCP prophylaxis; used in combination with pyrimethamine for prevention of toxoplasmosis in AIDS patients; used for various dermatologic disorders and topically…

  • Clofazimine

    Brands Classes DEA Class; Rx Common Brand Names; Lamprene Antitubercular Agents Description Exerts a slow bactericidal effect on Mycobacterium leprae (Hansen’s bacillus); inhibits mycobacterial growth and binds preferentially to mycobacterial DNA Also exerts anti-inflammatory properties in controlling erythema nodosum leprosum reactions; however, its precise mechanisms of action are unknown Indications Indicated for treatment of lepromatous…

  • Ethionamide

    Brands Classes DEA Class; Rx Common Brand Names; Trecator Antitubercular Agents Description Second-line agent for tuberculosis; for disease resistant to rifampin and/or isoniazid, or for patients who are intolerant of rifampin and isoniazid; used in combination with at least one other antitubercular drug; only film-coated tablets (Trecator®) available. Indications Indicated for the treatment of drug-susceptible…

  • Cycloserine

    Brands Classes DEA Class; Rx Common Brand Names; Capastat Antitubercular Agents Description Bacteriostatic or bactericidal Inhibits cell wall synthesis Indications Indicated for treatment of Tuberculosis Contraindications Hypersensitivity Alcohol use Renal dysfunction, severe History of seizure disorder, mental depression, severe anxiety or psychosis Adverse Effects Confusion Restlessness Drowsiness Vertigo Cardiac arrhythmia Folate deficiency Hyperreflexia Dysarthria Dizziness…

  • Capreomycin

    Brands Classes DEA Class; Rx Common Brand Names; Capastat Antitubercular Agents Description Parenteral polypeptide antibiotic, exact mechanism unknown.Used as a second line agent in combination with other medications for the treatment of pulmonary tuberculosis.Practical use is limited by routes of administration, adverse effects of nephrotoxicity and neurotoxicity. Indications Indicated for treatment of Tuberculosis Contraindications Hypersensitivity…

  • Aminosalicylic Acid

    Brands Classes DEA Class; Rx Common Brand Names; Paser 5-Aminosalicylic Acid Derivatives;  Antitubercular Agents Description Oral antituberculosis agent that may inhibit folic acid synthesis and/or inhibit synthesis of a cell wall component Use second-line to treat tuberculosis infection; often used for multi-drug resistant tuberculosisMust be used as part of a multi-drug treatment regimen Indications Indicated for…

  • Bedaquiline

    Brands Classes DEA Class; Rx Common Brand Names; Sirturo Antitubercular Agents Description Diarylquinoline antimycobacterialFor use in combination with other drugs to treat adults and pediatric patients 5 years and older weighing at least 15 kg with pulmonary multi-drug resistant tuberculosis (MDR-TB) for which no other effective treatment regimens are availableAssociated with an increased risk of…

  • Rifapentine

    Brands Classes DEA Class; Rx Common Brand Names; Priftin Antitubercular Agents Description Oral cyclopentyl rifamycin antimycobacterial drugUsed for treatment of active pulmonary tuberculosis (TB) in combination with 1 or more anti-TB drugs and treatment of latent TB infection in patients at high risk of progression to TB diseaseHepatotoxicity and drug-drug interactions may limit use Indications…

  • Rifampin

    Brands Classes DEA Class; Rx Common Brand Names; Rifadin, Rimactane Antitubercular Agents Description Semisynthetic rifamycin antibioticPrimarily used as part of first-line, combination therapy for the treatment of tuberculosis and also used to treat asymptomatic carriers of Neisseria meningitidisPotent inducer of hepatic microsomal enzymes and associated with many significant drug interactions Indications Indicated for Tuberculosis.Indicated for…

  • Rifabutin

    Brands Classes DEA Class; Rx Common Brand Names; Mycobutin Antitubercular Agents Description Antimycobacterial agent; alternative to clarithromycin or azithromycin for MAC prophylaxis; alternative to rifampin for TB prophylaxis or treatment. Indications Indicated for prevention of disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infectionOrphan designation for treatment of disseminated Mycobacterium avium complex…

  • Pyrazinamide

    Generic Only Classes DEA Class; Rx Common Brand Names; Nydrazid Antitubercular Agents Description Antituberculosis agent; useful when resistance to isoniazid or rifampin has been confirmed; used in combination with other agents. Indications Indicated for the treatment of drug-susceptible tuberculosis infection as part of combination therapy.For the treatment of drug-resistant tuberculosis infection as part of combination…