Tag: Antimalarial

Brands Classes DEA Class; Rx Common Brand Names; Qualaquin Antimalarials;  Description Antimalarial; occurs naturally in the bark of the cinchona tree; more toxic and potent antimalarial than quinidine; FDA ruled that it lacked evidence of effectiveness for relief of nocturnal muscle cramps; non-prescription forms are no longer available but prescription forms are still available. Indications Indicated…

Brands Classes DEA Class; Rx Common Brand Names; Primaquine Antimalarials;  Antimalarials, Aminoquinoline Description Oral antimalarial agent; chemically related to chloroquine; not effective against asexual erythrocytic forms; alternative agent for PCP in combination with clindamycin. Indications Indicated for the radical cure (prevention of relapse) of malaria due to P. vivax or P. ovale in patients who are receiving appropriate antimalarial…

Brands Classes DEA Class; Rx Common Brand Names; Lariam Antimalarials Description Oral antimalarial agent used for malaria prophylaxis or treatment. Prophylactic dosing should begin 1 week before entering endemic area and continue for 4 weeks after leaving. Alternative antimalarial in areas where chloroquine- and proguanil-resistant strains of malaria exist (i.e., European countries). Treatment of choice for…

Brands Classes DEA Class; Rx Common Brand Names; Malarone Antimalarials Description Oral antimalarial combination with potent synergistic antimalarial activity. Atovaquone is structurally and pharmacologically related to the older antimalarials, lapinone and parvaquone. Proguanil is a synthetic biguanide derivative of pyrimidine and a prodrug for cycloguanil. Certain populations are poor metabolizers (e.g., Asian and African populations) of…

Brands Classes DEA Class; Rx Common Brand Names; Mepron Antimalarials Description Oral antiprotozoal agent; active against both Toxoplasma gondii and Pneumocystis jiroveci (formerly Pneumocystis carinii); structurally and pharmacologically related to lapinone and parvaquone (antimalarials); effective for malaria when used with proguanil. Indications Indicated for the treatment Pneumocystis Carinii Pneumonia Malaria (P. falciparum) Contraindications History of hypersensitivity…

Brands Classes DEA Class; Rx Common Brand Names; Coartem Antimalarials Description Fixed artemisinin-based combination tabletFor the treatment of acute, uncomplicated malaria infections in patients 2 months and older with a bodyweight of at least 5 kgArtemisinin-based therapies are potent with rapid onset of anti-parasitic activity Indications Indicated for the treatment of malaria. Contraindications Hypersensitivity Coadministration with…