Tag: Antihypertensives
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Hydrochlorothiazide/Aliskiren
Brands Classes DEA Class; Rx Common Brand Names; Tekturna HCT Renin Inhibitors/Combos Description Aliskiren, a direct renin inhibitor, and hydrochlorothiazide, a thiazide diuretic, are combined in 1 tablet to treat hypertension. Indications Indicated for the treatment of hypertension. Contraindications Hypersensitivity to aliskiren, hydrochlorothiazide, or sulfonamides Anuria Concomitant use with ACEIs or ARBs in patients with…
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Eprosartan/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Teveten HCT, Teveten Plus ARB/HCTZ Combos Description Angiotensin II antagonist and thiazide diuretic used together for management of HTN; additive efficacy; less potassium loss compared to diuretic monotherapy. Indications Indicated for the treatment of hypertension in patients who do not respond to monotherapy. Contraindications Hypersensitivity to eprosartan,…
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Olmesartan/Amlodipine/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Tribenzor ARB/CCB/Diuretic Combos Description Combination product containing a dihydropyridine calcium-channel blocker (amlodipine), an angiotensin II receptor blocker (ARB, olmesartan) and a thiazide diuretic (hydrochlorothiazide, HCTZ)Used for the maintenance treatment of HTN in adults after titration of individual drugs Indications Indicated for the treatment of hypertension. Contraindications…
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Valsartan/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Diovan HCT ARB/HCTZ Combos Description Angiotensin II blocker and thiazide diuretic once-daily productUsed for hypertensionAdditive efficacy; less potassium loss than with hydrochlorothiazide alone. Indications Indicated for the treatment of hypertension. Contraindications Hypersensitivity to valsartan, hydrochlorothiazide, or sulfonamides Anuria Coadministration with aliskiren in patients with diabetes Adverse…
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Spironolactone/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Aldactazide Thiazide Combos Description Combination oral diuretic product; potassium-sparing diuretic (aldosterone antagonist) and thiazide diureticFor treatment of hypertension or edema (not initial treatment)Useful for patients with hyperaldosteronism or hypokalemia Indications Indicated for the treatment of edema associated with cirrhosis of the liver, congestive heart failure, or the…
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Triamterene/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Dyazide, Maxzide Thiazide Combos Description Thiazide diuretic and a potassium-sparing diureticUsed for hypertension and edemaTriamterene counteracts potassium loss caused by hydrochlorothiazide; efficacy is diminished in patients with renal insufficiency. Indications Indicated for the treatment of peripheral edema or hypertension. Contraindications Hypersensitivity to triamterene, hydrochlorothiazide, or sulfonamides (hydrochlorothiazide…
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Candesartan/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Atacand HCT ARB/HCTZ Combos Description Angiotensin II antagonist and thiazide diuretic used together for management of HTN; additive efficacy; less potassium loss compared to diuretic monotherapy. Indications Indicated for the treatment of hypertension in patients who do not respond to monotherapy. Contraindications Hypersensitivity to candesartan, hydrochlorothiazide, or…
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Aliskiren/Amlodipine/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Amturnide Renin Inhibitors/Combos; Antianginal Agents; Calcium Channel Blockers, Dihydropyridine; CCB/Renin Inhibitor/HCTZ Combos Description Combination direct renin inhibitor (aliskiren), dihydropyridine calcium-channel blocker (amlodipine), and thiazide diuretic (hydrochlorothiazide)Used for hypertensionBlack box warning for use during pregnancy Indications Indicated for the treatment of hypertension. Contraindications Hypersensitivity to aliskiren, amlodipine, hydrochlorothiazide,…
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Enalapril/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Vaseretic ACEI/Diuretic Combos; ACEI/HCTZ Combos Description ACE inhibitor and thiazide diuretic; additive efficacy in HTN; given once or twice daily; counters the potassium loss from HCTZ; more effective than ACE monotherapy in black patients. Indications Indicated for the treatment of hypertension. Contraindications Hypersensitivity to ACE inhibitors, thiazides…
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Lisinopril/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Zestoretic ACEI/Diuretic Combos; ACEI/HCTZ Combos Description ACE inhibitor and thiazide diuretic combinationUsed for hypertension once dailyLisinopril counteracts the potassium loss from hydrochlorothiazide; more effective than ACE monotherapy in Black patients. Indications Indicated for the treatment of hypertension in patients who do not respond to monotherapy. Contraindications Hypersensitivity…
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Hydralazine/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Hydra-Zide Thiazide Combos Description Hydralazine/hydrochlorothiazide is a fixed-combination tablet that combines a vasodilator, hydralazine and a thiazide diuretic, hydrochlorothiazide Hydralazine, a direct vasodilator, dilates arterioles with little effect on veins; decreases systemic resistance Hydrochlorothiazide, a thiazide diuretic, inhibits Na reabsorption in distal renal tubules resulting in increased…
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Olmesartan/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Benicar HCT ARB/HCTZ Combos Description Oral antihypertensive combination product containing an angiotensin II receptor antagonist and thiazide diureticUsed for the management of hypertension in adultsAdditive blood pressure reduction Indications Indicated for the treatment of hypertension in patients who do not respond to monotherapy. Contraindications Hypersensitivity to olmesartan,…
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Benazepril/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Lotensin HCT ACEI/Diuretic Combos; ACEI/HCTZ Combos Description Combination product for HTN; contains ACE inhibitor and thiazide diuretic; additive efficacy in HTN; can be dosed qd; counters the potassium loss from HCTZ. Indications Indicated for the treatment of hypertension. Not for initial therapy Contraindications Hypersensitivity to either component…
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Captopril/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Capozide ACEI/Diuretic Combos; ACEI/HCTZ Combos Description Combination ACE inhibitor and thiazide diuretic; usually given 2—3 times daily; additive efficacy in HTN; counters the potassium loss from HCTZ; more effective than ACE monotherapy in black patients; captopril contains a sulfhydryl group and is shortest-acting. Indications Indicated for the…
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Quinapril/Hydrochlorothiazide
Brands Classes DEA Class; Rx Common Brand Names; Accuretic ACEI/Diuretic Combos; ACEI/HCTZ Combos Description ACE inhibitor and thiazide diureticUsed for hypertensionCounteracts the potassium loss from hydrochlorothiazide; more effective than ACE monotherapy in Black patients Indications Indicated for the treatment of hypertension. Contraindications Anuria Hypersensitivity to either component or sulfonamides History of angioedema Hereditary or idiopathic…