Tag: Antihypertensives
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Hydralazine
Brands Classes DEA Class; Rx Common Brand Names; Apresoline Vasodilators Description Oral and parenteral vasodilator; used for HTN and CHF, although ACE inhibitors have largely replaced hydralazine for CHF; used for HTN during pregnancy; also used to treat pulmonary hypertension; its use in the general population for HTN has declined due to adverse effects and…
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Verapamil
Brands Classes DEA Class; Rx Common Brand Names; Isoptin SR, Calan SR, Covera HS, Isoptin, Isoptin IV, Calan, Verap, Verapamil SR, Verelan, Verelan PM Antidysrhythmics, IV; Calcium Channel Blockers; Calcium Channel Blockers, Non-dihydropyridine Description Oral and IV calcium-channel blocker; used for angina, HTN, and supraventricular tachyarrhythmias; class IV antiarrhythmic agent; more effective than digoxin for controlling…
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Nisoldipine
Brands Classes DEA Class; Rx Common Brand Names; Sular Calcium Channel Blockers; Calcium Channel Blockers, Dihydropyridine Description Long-acting, oral, dihydropyridine calcium-channel blocker; similar to nifedipine, but has greater affinity and selectivity for vascular smooth muscle, produces 5-10 times greater peripheral vasodilation, and has a longer half-life allowing QD dosing; approved for HTN; off-label for…
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Nifedipine
Brands Classes DEA Class; Rx Common Brand Names; Procardia, Procardia XL, Adalat CC, Nifedical XL, Adalat, Afeditab CR, Nifediac CC Calcium Channel Blockers; Calcium Channel Blockers, Dihydropyridine Description Oral calcium-channel blocker; prototype dihydropyridine with more prominent effects on vasodilation and coronary flow than diltiazem and verapamil; lacks effects on AV conduction; primarily used for angina, Prinzmetal’s…
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Nicardipine
Brands Classes DEA Class; Rx Common Brand Names; Cardene IV, Cardene SR Calcium Channel Blockers; Calcium Channel Blockers, Dihydropyridine Description Oral and intravenous dihydropyridine calcium channel blockerUsed for angina and hypertensionPotent vasodilator more selective to vascular smooth muscle than cardiac muscle Indications Indicated for the treatment of chronic stable angina. For the treatment of hypertension.For the…
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Isradipine
Brands Classes DEA Class; Rx Common Brand Names; DynaCirc Calcium Channel Blockers; Calcium Channel Blockers, Dihydropyridine Description Dihydropyridine calcium-channel blockerUsed for hypertension and anginaMore potent than nifedipine and amlodipine; longer-acting than regular-release nifedipine but shorter-acting than amlodipine Indications Indicated for the treatment of hypertension. For the treatment of chronic stable angina.For the treatment of hypertensive…
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Felodipine
Brands Classes DEA Class; Rx Common Brand Names; Cabren, Cardioplen XL, Felendil XL, Felogen XL, Felotens XL, Keloc SR, Neofel XL, Plendil, Renedil, Vascalpha Calcium Channel Blockers; Calcium Channel Blockers, Dihydropyridine Description Oral, dihydropyridine calcium-channel blocker; used for HTN and angina (off-label use); potent peripheral vasodilator similar to nifedipine, but with greater selectivity for vascular smooth…
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Diltiazem
Brands Classes DEA Class; Rx Common Brand Names; Cardizem, Cardizem CD, Cardizem LA, Cartia XT, Dilacor, Dilacor XR, Dilatrate, Diltazem, Diltazem CD, Dilt-CD, Diltia XT, Diltiaz, Diltiaz CD, Diltiaz SR, Diltiazem CD, Diltiazem SR, Dilzem, Taztia XT, Tiazac Antidysrhythmics, IV; Calcium Channel Blockers; Calcium Channel Blockers, Non-dihydropyridine Description Oral and IV, benzothiazepine calcium-channel blocker; primarily used…
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Clevidipine
Brands Classes DEA Class; Rx Common Brand Names; Cleviprex Calcium Channel Blockers; Calcium Channel Blockers, Dihydropyridine Description Intravenous dihydropyridine calcium channel blockerUsed for hypertension when oral therapy is not feasible or desirableDelivered in a lipid emulsion vehicle Indications Indicated for the treatment of hypertension when oral therapy is not feasible or desirable. Contraindications Hypersensitivity…
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Amlodipine/Atorvastatin
Brands Classes DEA Class; Rx Common Brand Names; Caduet Calcium Channel Blockers; Lipid-Lowering Agents, Statins; Calcium Channel Blockers, Dihydropyridine; HMG-CoA Reductase Inhibitors Description Combination calcium-channel blocker and HMG-CoA reductase inhibitor; used for HTN or angina with hyperlipidemia in patients who were previously receiving the individually titrated drug components Indications Indicated for the treatment of hypertension…
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Valsartan/Amlodipine
Brands Classes DEA Class; Rx Common Brand Names; Exforge ARB/CCB Combos Description Dihydropyridine calcium-channel blocker (amlodipine) combined with angiotensin II antagonist (valsartan); both drugs have long half-lives allowing for qd dosing; used primarily for tx of HTN after titration of individual drugs. Indications Indicated for the treatment of hypertension. Contraindications Hypersensitivity to valsartan, amlodipine, or…
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Amlodipine
Brands Classes DEA Class; Rx Common Brand Names; Norvasc, Katerzia, Norliqva Antianginal Agents; Calcium Channel Blockers, Dihydropyridine Description Oral dihydropyridine calcium channel blocker; potent peripheral vasodilatorUsed for hypertension and anginaOnce daily dosing due to long half-life Indications Indicated for the treatment of hypertension. For the treatment of coronary artery disease (CAD), including chronic stable angina, variant…
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Trandolapril/Verapamil
Brands Classes DEA Class; Rx Common Brand Names; Tarka ACE Inhibitors Description ACE inhibitor and CCB; used qd for HTN; oral combination product contains immediate-release trandolapril and extended-release verapamil; has greater antihypertensive effects than either agent alone. Indications Indicated for the treatment of hypertension. Not indicated for initial therapy For the treatment of hypertension in…
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Trandolapril
Brands Classes DEA Class; Rx Common Brand Names; Mavik ACE Inhibitors Description Oral ACE inhibitor; structurally similar to enalapril, requiring hydrolysis for activity; used once daily for HTN and to reduce cardiovascular morbidity and mortality following AMI. Indications Indicated for the treatment of hypertension. For the treatment of heart failure postmyocardial infarction or left-ventricular dysfunction…
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Ramipril
Brands Classes DEA Class; Rx Common Brand Names; Altace ACE Inhibitors Description ACE inhibitor; prodrug metabolized to active ramiprilat; used 1—2 times daily for HTN; also used to reduce proteinuria and slow the progression of renal disease from various nephropathies; given twice daily for CHF, AMI, and post-MI. Indications Indicated for reduction of cardiovascular mortality,…