Tag: Antifungal

  • Ciclopirox

    Brands Classes DEA Class; Rx Common Brand Names; Loprox, Penlac Antifungals, Topical Description Antifungal agent; 1% cream or lotion used topically for tinea infections; 8% nail solution used for onychomycosis; 1% shampoo for seborrheic dermatitis of the scalp. Indications Indicated for the treatment of Mild to Moderate Onychomycosis of Fingernails & Toenails Tinea Pedis or…

  • Clotrimazole

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Gyne-Lotrimin-3 Combination Pack, Gyne-Lotrimin-3 Vaginal Cream, Gyne-Lotrimin-3 Vaginal Suppositories, Gyne-Lotrimin-7, Mycelex-7, Mycelex-7 Combination Pack, Mycelex vaginal, Gyne Lotrimin, Lotrimin, Lotrimin AF, Mycelex topical Antifungals, Topical Description Imidazole antifungal agent marketed in a variety of preparations including vaginal suppositories and cream, topical lotion and cream, topical solution, and…

  • Butoconazole

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Femstat 3, Gynazole 1 Antifungals, Vaginal Description Imidazole antifungal agent that is fungicidal in vitro against Candida spp.; available as a vaginal preparation; multiple dose products available OTC; single dose product available by prescription only. Indications Indicated for the treatment of vulvovaginal candidiasis (VVC). Contraindications Hypersensitivity…

  • Butenafine

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Lotrimin Ultra, Mentax, Mentax-TC Antifungals, Topical Description Topical antifungal agent; structurally similar to the allylamines (e.g., naftifine and terbinafine); active against a variety of superficial dermatophytes responsible for causing tinea pedis, tinea corporis, and tinea cruris. Indications Indicated for the topical treatment of tinea corporis, tinea cruris,…

  • Voriconazole

    Brands Classes DEA Class; Rx Common Brand Names; Vfend Antifungals, Systemic;  Description IV and oral azole antifungal drugIndicated for aspergillosis, candidiasis, candidemia, and as salvage therapy for Scedosporium and Fusarium sp. infectionsAssociated with visual disturbances, QT prolongation, and phototoxicity Indications In clinical trials, the majority of isolates recovered were Aspergillus fumigatus Indicated for candidemia in…

  • Posaconazole

    Brands Classes DEA Class; Rx Common Brand Names; Noxafil Antifungals, Systemic;  Description Oral and intravenous azole antifungal agentUsed for the treatment of invasive aspergillosis and oropharyngeal candidiasis and for prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patientsOral dose formulations not interchangeable due to differences in dosing Indications Oral suspension or delayed-release tablets…

  • Micafungin

    Brands Classes DEA Class; Rx Common Brand Names; Mycamine Antifungals, Systemic;  Antifungals, Echinocandin Description Echinocandin antifungalUsed for Candida infection prophylaxis and treatmentEfficacy for treatment of infections caused by fungi other than Candida has not been established Indications Indicated for the treatment of Treatment of candidemia, acute disseminated candidiasis, candida peritonitis and abscesses Treatment of Esophageal…

  • Ketoconazole

    Brands Classes DEA Class; Rx Common Brand Names; Nizoral, Nizoral Topical, Extina, Ketozole, Xolegel Antifungals, Systemic;  Description Imidazole antifungalUsed topically for fungal skin and skin structure infections; used orally for serious fungal infections only when no other antifungal therapies availableOral use associated with fatal hepatotoxicity, adrenal gland suppression, and harmful drug interactions Indications Indicated for the…

  • Itraconazole

    Brands Classes DEA Class; Rx Common Brand Names; Sporanox, Onmel, Tolsura Antifungals, Systemic;  Description Oral, azole antifungal agentUsed for blastomycosis, histoplasmosis, aspergillosis, onychomycosis, and oropharyngeal or esophageal candidiasisDosage forms not interchangeable Indications Indicated for Life-threatening Infections Indicated for treatment of blastomycosis, including pulmonary and extrapulmonary infections in immunocompromised and nonimmunocompromised adults Indicated for treatment of pulmonary…

  • Isavuconazonium Sulfate

    Brands Classes DEA Class; Rx Common Brand Names; Cresemba, isavuconazole Antifungals, Systemic;  Description Oral and injectable azole antifungalUsed for the treatment of invasive aspergillosis or invasive mucormycosisBioequivalence between oral and intravenous formulations established Indications Indicated for invasive aspergillosis Has activity against most strains of the following microorganisms, both in vitro and in clinical infection: Aspergillus…

  • Flucytosine

    Brands Classes DEA Class; Rx Common Brand Names; Ancobon, 5-FC, 5-fluorocytosine Antifungals, Systemic;  Description Fluorinated pyrimidine antifungal agent; structurally similar to fluorouracil and floxuridine; used mainly in combination with amphotericin B for cryptococcal meningitis; use has decreased due to availability of new antifungals. Indications Indicated for treatment of Candidiasis/Cryptococcus Infection Other Indications & Uses Off-label: chromomycosis…

  • Fluconazole

    Brands Classes DEA Class; Rx Common Brand Names; Diflucan Antifungals, Systemic;  Description First triazole synthetic antifungal agentUsed for treatment of various Candida infections, cryptococcal meningitis, and prophylaxis in BMT patientsAssociated with increased incidence of Candida krusei when used for prophylaxis Indications Indicated for treatment of Oropharyngeal Candidiasis Esophageal Candidiasis Cryptococcal Meningitis Vaginal Candidiasis Candida UTI/Peritonitis…

  • Caspofungin

    Brands Classes DEA Class; Rx Common Brand Names; Cancidas Antifungals, Systemic;  Antifungals, Echinocandin Description IV echinocandin antifungalUsed for aspergillosis, candidemia, esophageal candidiasis, and empiric treatment in febrile neutropeniaFever and infusion-related reactions common Indications Includes candidemia and other Candida infections including intra-abdominal abscesses, peritonitis, and pleural space infectionsIndicated for treatment of esophageal candidiasisIndicated for invasive aspergillosis…

  • Anidulafungin

    Brands Classes DEA Class; Rx Common Brand Names; Eraxis Antifungals, Systemic;  Antifungals, Echinocandin Description IV echinocandin antifungal drugUsed for candidemia and other invasive candidiasis infections and esophageal and oropharyngeal candidiasisEfficacy for treatment of infections caused by fungi other than Candida has not been established Indications Indicated for treatment of candidemia and intra-abdominal abscess and peritonitis…

  • Amphotericin B

    Brands Classes amphotericin B deoxycholate (Rx) Brand and Other Names: amphotericin B (conventional) Classes: Antifungals, Systemic amphotericin B cholesteryl sulfate (Rx) Brand and Other Names: Amphotec Classes: Antifungals, Systemic amphotericin B phospholipid complex (Rx) Brand and Other Names: Abelcet Classes: Antifungals, Systemic amphotericin B liposomal (Rx) Brand and Other Names: AmBisome Classes: Antifungals, Systemic Description Polyene antifungal antibiotic similar to nystatin; despite many…