Tag: Antiepilepsy

Brands Classes DEA Class;  Rx Common Brand Names; Zonegran, Zonisade Anticonvulsants, Other Description Sulfonamide anticonvulsantUsed for adjunctive treatment of partial seizuresMonitor for suicidal thoughts/behavior or depression Indications Indicated as adjunctive therapy for partial seizures Contraindications Hypersensitivity to zonisamide or sulfonamides Adverse Effects Somnolence (17%) Anorexia (13%) Dizziness (13%) Headache (10%) Nausea (9%) Agitation/irritability (9%) Fatigue…

Brands Classes DEA Class;  Rx Common Brand Names; Sabril, Vigadrone Anticonvulsants, Other Description Oral anticonvulsant designed to inhibit GABA metabolismUsed for complex partial seizures and infantile spasmsRisk of permanent vision loss; only available through restricted distribution Indications Indicated for the treatment of infantile spasms. For the adjunctive treatment of refractory complex partial seizures. Contraindications —…

Brands Classes DEA Class;  Rx Common Brand Names; Qsymia CNS Stimulants, Anorexiants Description Combination of an anorectic sympathomimetic amine (phentermine) and carbonic anhydrase inhibitor antiepileptic (topiramate)Used for weight reduction and management in obese adults, overweight adults with at least 1 weight-related comorbidity, and pediatric patients 12 years and older with an initial BMI in the…

Brands Classes DEA Class;  Rx Common Brand Names; Topamax, Trokendi XR, Qudexy XR, Eprontia Anticonvulsants,Others Antimigraine Agents Description Oral anticonvulsant; weak carbonic anhydrase inhibitorUsed for partial and generalized seizures, Lennox-Gastaut, refractory seizures, and migraine prophylaxis; off-label uses include binge-eating disorder and alcohol use disorderClose monitoring for emerging or worsening suicidal thoughts/behavior or depression recommended Indications Indicated…

Brands Classes DEA Class;  Rx Common Brand Names; Gabitril Anticonvulsants,Others Description Oral anticonvulsant for partial seizures; unique MOA; inhibits reuptake of GABA; a therapeutic range for plasma concentrations has not been established; does not appear to affect hepatic microsomal enzymes; close monitoring for emerging or worsening suicidal thoughts/behavior or depression is recommended. Indications Indicated for…

Brands Classes DEA Class;  Rx Common Brand Names; Banzel Anticonvulsants,Others Description Triazole derivative anticonvulsantUsed for adjunctive treatment of seizures associated with Lennox-Gastaut syndromeApproved for use in patients >= 1 year Indications Indicated for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome. For the adjunctive treatment of refractory partial seizures. Contraindications Documented hypersensitivity Familial Short…

Brands Classes DEA Class;  Rx Common Brand Names; Mysoline Anticonvulsants, Barbiturates;  CYP3A4 Inducer, Strong Description Oral anticonvulsant related to barbiturates; metabolized to phenobarbital and another active metabolite; effective in all seizure disorders except absence; close monitoring for emerging or worsening suicidal thoughts/behavior or depression is recommended. Indications Indicated for use as an alternative to other…

Brands Classes DEA Class;  Rx Common Brand Names; Lyrica, Lyrica CR Analgesics, Other;  Anticonvulsants, Other;  Fibromyalgia Agents Description Oral compound chemically and structurally similar to gabapentin, with antiepileptic, analgesic, and anxiolytic propertiesUsed for neuropathic pain associated with diabetic peripheral neuropathy or spinal cord injury, postherpetic neuralgia, fibromyalgia, and adjunctive therapy for partial onset seizuresMonitor for…

Brands Classes DEA Class;  Rx Common Brand Names; Dilantin, Dilantin 125, Phenytek Anticonvulsants, Hydantoins;  Antidysrhythmics, Ib Description Oral and parenteral hydantoin anticonvulsant with narrow therapeutic window; used for tonic-clonic seizures and complex partial seizures; switching dosage forms may produce significant changes in serum concentrations; close monitoring for emerging or worsening suicidal thoughts/behavior or depression is recommended.…

Brands Classes DEA Class;  Rx Common Brand Names; Fycompa Anticonvulsants, AMPA Glutamate Antagonists Description Alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (AMPA) receptor antagonistUsed for partial-onset and primary generalized tonic-clonic seizuresBlack box warning for neuropsychiatric events Indications Indicated for the treatment of partial seizures. Indicated as adjunctive therapy for primary generalized tonic-clonic seizures in patients with epilepsy Contraindications Known hypersensitivity…

Brands Classes DEA Class;  Rx Common Brand Names; Trileptal, Oxtellar XR Anticonvulsants, Other Description Oral anticonvulsant that is a keto-analog of carbamazepine (CBZ); does not require routine drug concentration monitoringIndicated for partial seizures in adults and pediatric patients 2 years and older; used off-label for neuropathic pain in adultsClose monitoring for emerging or worsening suicidal…

Brands Classes DEA Class;  Rx Common Brand Names; Keppra, Keppra XR, Spritam, Elepsia SV2A Ligands Description Oral and intravenous pyrrolidine derivative antiepileptic drugUsed for the treatment of certain types of partial, myoclonic, and generalized tonic-clonic seizuresMonitor for emerging or worsening suicidal thoughts/behavior and depression Indications Indicated for treatment of partial-onset seizures For the adjunctive treatment of…

Brands Classes DEA Class;  Rx Common Brand Names; Horizant GABA Analogs Description Oral and injectable functionalized amino acid anticonvulsantUsed for partial onset and generalized tonic-clonic seizuresClinical study experience of intravenous lacosamide is limited to 5 days of consecutive treatment Indications Indicated as monotherapy or adjunctive therapy for partial onset seizures Contraindications None Adverse Effects Tablets…

Brands Classes DEA Class;  Rx Common Brand Names; Horizant GABA Analogs Description Oral analog of GABA.Used for restless legs syndrome, postherpetic and other neuralgias, and adjunctively for partial seizures; orphan drug for amyotrophic lateral sclerosis (ALS).Monitor for emerging or worsening suicidal thoughts or actions and/or depression. Indications Indicated for moderate-to-severe primary restless legs syndrome Indicated…

Brands Classes DEA Class;  Rx Common Brand Names; Neurontin, Gralise GABA Analogs Description Parenteral prodrug of phenytoin; hydantoin anticonvulsantUsed for status epilepticus, seizures during neurosurgery, and as a short-term substitution for oral phenytoinMay cause transient, infusion-related, paresthesias and pruritus; systemic adverse reactions identical to phenytoin Indications Indicated for the adjunctive treatment of partial seizures with…