DrugsAce

Tag: Antidepressants

  • Nortriptyline

    Brands Classes DEA Class;  Rx Common Brand Names; Pamelor, Aventyl Antidepressants, TCAs Description Tricyclic antidepressant (TCA) of the dibenzocycloheptene type; active metabolite of amitriptylineFDA-approved for major depression in adults; common off-label uses for neuropathic pain and anxiety disorders in adults.Boxed warning for use in pediatric patients and young adults due to risk for suicidality Indications…

  • Maprotiline

    Brands Classes DEA Class;  Rx Common Brand Names; Ludiomil Antidepressants, TCAs Description Tetracyclic antidepressant of dibenzo-bicyclo-octadiene derivation; efficacy is similar to the TCAs for depression; occasionally administered for other indications. Indications Indicated for the treatment of major depression. Contraindications Hypersensitivity Severe cardiovascular disorders Narrow angle glaucoma Within 14 days of MAO inhibitors may cause serotonin…

  • Imipramine

    Brands Classes DEA Class;  Rx Common Brand Names; Tofranil, Tofranil-PM Antidepressants, TCAs Description Tertiary amine tricyclic antidepressant; imipramine is metabolized to desipramine, an active metaboliteFDA-approved for use in adults for the treatment of depression; used off label for neuropathic pain and other usesUsed in children 6 years of age and older for nocturnal enuresisBoxed warning…

  • Desipramine

    Brands Classes DEA Class;  Rx Common Brand Names; Norpramin Antidepressants, TCAs Description Tricyclic antidepressant (TCA) of the dibenzazepine type; desipramine is the active metabolite of imipramineFDA-approved for major depression in adults; evidence for off-label uses is low compared to established first-line treatmentsBoxed warning for use in pediatric patients and young adults due to risk for…

  • Clomipramine

    Brands Classes DEA Class;  Rx Common Brand Names; Anafranil Antidepressants, TCAs Description Tricyclic antidepressant with significant serotonin reuptake inhibitor activity; anticholinergic and orthostatic effectsUsed primarily for obsessive-compulsive disorder (OCD) in adults and pediatric patients 10 years and olderBoxed warning for use in pediatric patients and young adults due to risk for suicidality Indications Indicated for treatment…

  • Amoxapine

    Brands Classes DEA Class;  Rx Common Brand Names; Asendin Antidepressants, TCAs Description Norepinephrine reuptake inhibitor with dopamine antagonist propertiesUsed for the treatment of major depression in adults, including depression with psychotic features, concurrent anxiety, or agitationRequires close monitoring in pediatrics and young adults due to increased risk of suicidality during the initial stages of treatment…

  • Amitriptyline/Perphenazine

    Brands Classes DEA Class;  Rx Common Brand Names;   Psychotherapeutic Combos Description Oral combination phenothiazine antipsychotic and tricyclic antidepressantUsed for schizophrenia and for moderate to severe anxiety/agitation and associated depressive symptomsBoxed warning for increased risk of suicidality in children, adolescents, and young adults during early treatment phase and increased mortality risk in elderly patients with dementia-related…

  • Amitriptyline

    Brands Classes DEA Class;  Rx Common Brand Names; Elavil, Levate Antidepressants, TCAs Description Tertiary amine tricyclic antidepressant; amitriptyline is metabolized to nortriptyline, an active metaboliteFDA-approved for use in adults for the treatment of depression; used off label for neuropathic pain and other usesBoxed warning for use in pediatric patients and young adults due to risk…

  • Vortioxetine

    Brands Classes DEA Class;  Rx Common Brand Names; Trintellix  Antidepressants, Other;  Description Oral antidepressant that is a serotonin modulator and stimulatorIndicated for major depressive disorder in adultsIncreased risk of suicidality during the initial stages of treatment in pediatric and young adult patients Indications Indicated for the treatment of major depression. Contraindications Hypersensitivity to vortioxetine or…

  • Vilazodone

    Brands Classes DEA Class;  Rx Common Brand Names; Viibryd  Antidepressants, Other;  Antidepressants, SSRI/5HT-1A Partial Agonist Description Oral antidepressant that modulates serotonin; a dual selective serotonin reuptake inhibitor and partial serotonin 5-HT1A agonistUsed for the treatment of major depressive disorder in adultsIncreased risk of suicidality during the initial stages of treatment in pediatric and young adult…

  • Trazodone

    Brands Classes DEA Class;  Rx Common Brand Names; Desyrel, Desyrel Dividose, Oleptro, Trazodone D Antidepressants, Other;  Description Oral selective serotonin reuptake inhibitor/serotonin type 2 receptor antagonist with significant sedative actionsApproved for use in adults for major depressive disorder, but commonly used off-label for insomniaBoxed warning for use in pediatric patients and young adults due to risk…

  • Nefazodone

    Brands Classes DEA Class;  Rx Common Brand Names; Serzone, Nefazodone 5HT2, Serzone 5HT2 Antidepressants, Other;  Antidepressants, SSRI/Antagonist Description Synthetic phenylpiperazine antidepressant; structurally similar to trazodone but exhibits less sedation and orthostasisUsed for treating major depression in adultsBoxed warning warns of risk of hepatotoxicityRequires close monitoring in pediatrics and young adults due to an increased risk of…

  • Mirtazapine

    Brands Classes DEA Class;  Rx Common Brand Names; Remeron, Remeron SolTab  Antidepressants, Alpha-2 Antagonists;  Antidepressants, Other Description Tetracyclic serotonergic and noradrenergic antidepressant unrelated to other classes of antidepressantsUsed for the treatment of major depressive disorder in adultsIncreased risk of suicidality during the initial stages of treatment in pediatric and young adult patients Indications Indicated for…

  • Bupropion/Naltrexone

    Brands Classes DEA Class;  Rx Common Brand Names; Contrave Antidepressants, Dopamine Reuptake Inhibitors;  Opioid Antagonists Description Combination of an aminoketone antidepressant (bupropion) and an opioid antagonist (naltrexone)Used for weight loss and management in obese adults or overweight adults with at least 1 weight-related comorbidityDo not take with other bupropion products; monitor for depression, mood changes,…

  • Bupropion

    Brands Classes DEA Class;  Rx Common Brand Names; Budeprion SR, Aplenzin, Buproban, Wellbutrin SR, Wellbutrin XL, Forfivo XL, Zyban (DSC) Antidepressants, Dopamine Reuptake Inhibitors;  Antidepressants, Other;  Smoking Cessation Aids Description Oral antidepressant of the aminoketone class; unrelated to other antidepressantsBrand-specific FDA approvals for major depression, seasonal affective disorder, and smoking cessation in adultsGreater potential for causing…