Tag: Anticoagulants

  • Warfarin

    Brands Classes DEA Class; Rx Common Brand Names; Coumadin, Jantoven Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic Description Coumarin anticoagulantUsed to prevent and treat thromboembolic diseaseMajor hemorrhagic risks have decreased due to the adoption of INR method of monitoring and decreasing the intensity of anticoagulation for most indications; observe for drug interactions Indications Indicated for general dosing information…

  • Rivaroxaban

    Brands Classes DEA Class; Rx Common Brand Names; Xarelto  Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic;  Factor Xa Inhibitors   Description Oral selective factor Xa inhibitor anticoagulantUsed for treatment and prophylaxis of thromboembolism in several clinical contexts in patients as young as neonatesRoutine laboratory monitoring not required Indications Indicated for stroke and systemic embolism prophylaxis in nonvalvular atrial…

  • Heparin

    Brands Classes DEA Class; Rx Common Brand Names; Hep-Lock, Hep-Lock U/P, Hepflush-10, Monoject Prefill Advanced Heparin Lock Flush, SASH Normal Saline and Heparin Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic Description A glycosaminoglycan anticoagulant; its molecular weight ranges from 5,000-30,000 daltons; derived from porcine or bovine tissue; produces a less predictable anticoagulant response than LMWH; used to prevent…

  • Fondaparinux

    Brands Classes DEA Class; Rx Common Brand Names; Arixtra Anticoagulants, Hematologic;  Factor Xa Inhibitors Description Pentasaccharide anticoagulant used SQ for the treatment of DVT and PE, and for DVT and PE prophylaxis in abdominal surgery, hip fracture surgery, and hip and knee replacement surgery. Inhibits factor Xa but not factor IIa (thrombin). Indications Indicated for…

  • Enoxaparin

    Brands Classes DEA Class; Rx Common Brand Names; Lovenox Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic Description Low molecular weight heparin (LMWH)Used for prophylaxis and management of systemic thromboembolismMore predictable anticoagulant response than unfractionated heparin Indications Indicated for the treatment of venous thromboembolism (VTE) including acute deep venous thrombosis (DVT) or pulmonary embolism (PE). For thrombosis prophylaxis.For the…

  • Edoxaban

    Brands Classes DEA Class; Rx Common Brand Names; Savaysa Factor Xa Inhibitors Description Oral anticoagulantFor risk reduction of stroke in atrial fibrillation and treatment of DVT and PE after initial injectable therapyDose reduction required in some patients treated for DVT or PE and a CrCl of 15 to 50 mL/min or a body weight of…

  • Desirudin

    Discontinued Classes DEA Class; Discontinued Common Brand Names; Iprivask Anticoagulants, Hematologic;  Thrombin Inhibitors Description Parenteral recombinant analog of thrombin inhibitor hirudin; used for preventing DVT in patients undergoing elective hip replacement surgery; studied for acute coronary syndromes. Indications Indicated for deep venous thrombosis (DVT) prophylaxis in patients undergoing elective hip replacement surgery. For patients with…

  • Dalteparin

    Brands Classes DEA Class; Rx Common Brand Names; Fragmin Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic Description Low molecular weight heparinUsed for DVT prophylaxis, treatment of VTE, and prophylaxis of ischemic complications in unstable angina and non-Q-wave MIConsists of heparin molecules ranging in size from 2,000 to 9,000 daltons (14% to 26% are more than 8,000 daltons) Indications…

  • Dabigatran

    Brands Classes DEA Class; Rx Common Brand Names; Pradaxa Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic;  Thrombin Inhibitors Description Oral direct thrombin inhibitorUsed in adults for reduction of risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation, for treatment and reduction in risk of recurrence of DVT and PE, and for the prophylaxis of DVT…

  • Bivalirudin

    Brands Classes DEA Class; Rx Common Brand Names; Angiomax, Angiomax RTU Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic Description Intravenous direct thrombin inhibitorUsed for anticoagulation in patients undergoing PCI, including patients with HIT or HITTSAssociated with higher incidence of acute stent thrombosis in STEMI patients undergoing PCI compared to heparin Indications Use as anticoagulant in heparin-induced thrombocytopenia (HIT)…

  • Betrixaban

    Brands Classes DEA Class; Rx Common Brand Names; Bevyxxa Factor Xa Inhibitors Description Oral factor Xa inhibitorUsed for VTE prophylaxis in adults hospitalized for acute medical illness who are at risk for VTE due to moderate or severe restricted mobility or other risk factorsCan not monitor anticoagulant effect with standard lab testing; effect not readily…

  • Argatroban

    Brands Classes DEA Class; Rx Common Brand Names; Acova Anticoagulants, Cardiovascular;  Anticoagulants, Hematologic;  Thrombin Inhibitor Description Intravenous, direct thrombin inhibitorUsed for thrombosis prophylaxis or treatment in patients with heparin-induced thrombocytopenia (HIT) and as an anticoagulant in patients with or at risk of HIT undergoing percutaneous coronary intervention (PCI)Hepatically eliminated, can use in end-stage renal disease…

  • Apixaban

    Brands Classes DEA Class; Rx Common Brand Names; Eliquis Anticoagulants, Cardiovascular;  Factor Xa Inhibitors Description Oral and selective factor Xa inhibitor anticoagulantUsed for prevention of stroke and other systemic embolism in patients with nonvalvular atrial fibrillation, prevention of DVT in patients undergoing hip or knee replacement surgery, treatment of DVT or PE, and reduction in…