DrugsAce

Tag: Anticancer Drugs

  • Cetuximab

    Brands Classes DEA Class; Rx Common Brand Names; Erbitux Antineoplastics, Monoclonal Antibody;  Antineoplastics, EGFR Inhibitor Description Anti-EGFR monoclonal antibodyUsed for EGFR-positive, Ras wild-type, metastatic colorectal cancer (mCRC); BRAF V600E-mutated mCRC; and locally advanced or metastatic head and neck cancerCan cause serious infusion reactions and cardiopulmonary arrest; dermatologic toxicities are common Indications Indicated for KRAS mutation-negative…

  • Bevacizumab

    Brands Classes DEA Class; Rx Common Brand Names; Avastin, Mvasi, bevacizumab-awwb, Zirabev, bevacizumab-bvzr, Alymsys, bevacizumab-maly, bevacizumab-adcd, Vegzelma Antineoplastics, Monoclonal Antibody;  Antineoplastics, VEGF Inhibitor Description Humanized monoclonal antibody against vascular endothelial growth factorUsed for metastatic colorectal cancer, hepatocellular cancer, renal cell cancer, non-small cell lung cancer, cervical cancer, recurrent glioblastoma, and epithelial ovarian, fallopian tube, or primary…

  • Triptorelin

    Brands Classes DEA Class; Rx Common Brand Names; Trelstar Depot, Triptodur, Trelstar, Trelstar LA Antineoplastics, GNRH Agonist Description Agonist analog of gonadotropin-releasing hormone (GnRH)Used for the palliative treatment of advanced prostate cancer and the treatment of central precocious pubertyDepression, including rare reports of suicidal ideation and attempt, has been reported with GnRH agonists in children treated…

  • Letrozole

    Brands Classes DEA Class; Rx Common Brand Names; Femara Antineoplastics, Aromatase Inhibitor Description Nonsteroidal oral aromatase inhibitorUsed in postmenopausal women as adjuvant therapy for early breast cancer, extended adjuvant therapy after completion of 5 years of tamoxifen, and for advanced breast cancer; used off-label for infertility, idiopathic short stature in boys, and delayed puberty in…

  • Fulvestrant

    Brands Classes DEA Class; Rx Common Brand Names; Faslodex Antineoplastics, Estrogen Receptor Antagonist Description Estrogen-receptor antagonist without any known estrogen agonist effectsUsed in postmenopausal women as monotherapy or in combination with ribociclib for first- and second-line treatment of HR-positive, HER2-negative advanced breast cancer, and in combination with palbociclib or abemaciclib in women with HR-positive, HER2-negative…

  • Exemestane

    Brands Classes DEA Class; Rx Common Brand Names; Aromasin Antineoplastics, Aromatase Inhibitor Description Oral, irreversible, steroidal aromatase inhibitor for early breast cancer (estrogen-receptor positive after 2 to 3 years of tamoxifen therapy) or advanced breast cancerLacks cross-resistance with other aromatase inhibitors or tamoxifen; more complete estrogen blockade than anastrazole or letrozoleSimilar response rate to megestrol…

  • Anastrozole

    Brands Classes DEA Class; Rx Common Brand Names; Arimidex Antineoplastics, Aromatase Inhibitor Description Selective non-steroidal aromatase inhibitorUsed for the treatment of breast cancer in postmenopausal womenImproved disease-free survival compared with tamoxifen as adjuvant therapy for early breast cancer; overall survival was similar Indications Breast Cancer Adjuvant treatment Indicated for adjuvant treatment of postmenopausal women with…

  • Vinorelbine

    Brands Classes DEA Class; Rx Common Brand Names; Navelbine Antineoplastics, Vinca Alkaloid Description Semi-synthetic vinca alkaloid; microtubule inhibitorUsed for the treatment of metastatic non-small cell lung cancerVesicant; closely monitor for signs and symptoms of extravasation Indications Indicated for the treatment of non-small cell lung cancer (NSCLC). Indicated for metastatic non-small cell lung cancer (NSCLC) Indicated…

  • Vincristine Liposomal

    Brands Classes DEA Class; Rx Common Brand Names; Marqibo Antineoplastics, Vinca Alkaloid Description Liposome-encapsulated formulation of vincristine sulfate, a vinca alkaloid agentUsed for the treatment of adult patients with relapsed Philadelphia chromosome-negative ALLNeurologic toxicity (e.g., peripheral neuropathy and paralytic ileus) and myelosuppression have been reported Indications Indicated for treating Philadelphia chromosome-negative acute lymphoblastic leukemia in…

  • Vincristine

    Brands Classes DEA Class; Rx Common Brand Names; Velban Antineoplastics, Vinca Alkaloid Description A vinca alkaloid agentUsed for acute leukemias in pediatric and adult patients; used as part of combination therapy for Hodgkin lymphoma, non-Hodgkin lymphoma, rhabdomyosarcoma, neuroblastoma, and Wilms tumorFor IV use only; may be fatal if given as an intrathecal injection Indications For…

  • Paclitaxel Protein Bound

    Brands Classes DEA Class; Rx Common Brand Names; Abraxane Antineoplastics, Antimicrotubular Description Nanoparticle albumin-bound taxane; a microtubule inhibitorUsed for metastatic breast cancer, locally advanced or metastatic NSCLC, and metastatic pancreatic cancerDo not start a new cycle if ANC is less than 1,500 cells/mm3; myelosuppression requires monitoring and possible adjustments in therapy Indications Indicated for metastatic…

  • Vinblastine

    Brands Classes DEA Class; Rx Common Brand Names; Velban Antineoplastics, Vinca Alkaloid Description Vinblastine is a member of the Vinca alkaloid antineoplastic agents; extracted from the periwinkle plant; similar to vincristine in action and structure, but the alkaloids significantly differ in toxicities and spectrum of activity; the dose-limiting toxicity of vinblastine is bone-marrow suppression. Indications…

  • Paclitaxel

    Brands Classes DEA Class; Rx Common Brand Names; Taxol Antineoplastics, Antimicrotubular (Taxanes) Description Semisynthetic, diterpenoid taxane derivative from the bark of the Pacific yew tree; sequence of administration in combination with other agents is important in toxicity and efficacy; effective in numerous disease including breast, lung, ovarian, and bladder cancers, Kaposi’s sarcoma alone or as…

  • Docetaxel

    Brands Classes DEA Class; Rx Common Brand Names; Taxotere Antineoplastics, Antimicrotubular (Taxanes) Description A taxane microtubule inhibitorUsed for certain types of breast cancer, non-small cell lung cancer, gastric cancer, prostate cancer, and head and neck cancerOral corticosteroid premedication required prior to each dose to reduce the incidence and severity of hypersensitivity, fluid retention, and skin…

  • Temozolomide

    Brands Classes DEA Class; Rx Common Brand Names; Temodar Antineoplastics, Alkylating Description Alkylating antineoplastic agentUsed for the treatment of newly diagnosed glioblastoma multiforme and refractory anaplastic astrocytomaSevere hematologic toxicity and hepatotoxicity have been reported Indications Indicated for the treatment of adults with refractory anaplastic astrocytoma (ie, patients with disease progression on a drug regimen containing…