Tag: Anticancer Drugs

Brands Classes DEA Class; Rx Common Brand Names; Eloxatin Antineoplastics, Alkylating;  Antineoplastics, Platinum Analog Description Non cell-cycle specific, platinum-based alkylating agentUsed for the treatment of colorectal cancer, in combination with fluorouracil and leucovorinAcute or delayed neuropathy can occur; avoid the topical application of ice, as cold temperatures may exacerbate acute neuropathy Indications Indicated in combination…

Brands Classes DEA Class; Rx Common Brand Names; Opdivo Antineoplastics, Monoclonal Antibody;  PD-1/PD-L1 Inhibitors Description Programmed death receptor-1 (PD-1) blocking monoclonal antibodyUsed for certain types of colorectal cancer, esophageal cancer, gastric cancer, gastroesophageal junction (GEJ) cancer, head and neck cancer, hepatocellular cancer, Hodgkin lymphoma, melanoma, mesothelioma, non-small cell lung cancer, renal cell cancer, and urothelial…

Brands Classes DEA Class; Rx Common Brand Names; Revlimid Antineoplastics, Angiogenesis Inhibitor Description Biologic response modifier with immunomodulatory, antiangiogenic, and antineoplastic propertiesUsed for adult patients with myelodysplastic syndrome, multiple myeloma, mantle cell lymphoma, follicular lymphoma, and marginal zone lymphomaRisk of birth defects or embryo-fetal death if used during pregnancy; routine testing required; prescribers, pharmacies Indications…

Brands Classes DEA Class; Rx Common Brand Names; Ninlaro Antineoplastics, Proteasome Inhibitors Description Oral proteasome inhibitorUsed in combination with lenalidomide and dexamethasone for the treatment of multiple myeloma in patients who have received at least 1 prior treatmentMyelosuppression has been reported Indications Multiple Myeloma Indicated in patients who have received at least 1 prior therapy…

Brands Classes DEA Class; Rx Common Brand Names; VePesid, Toposar, Etopophos, vp 16 Antineoplastics, Podophyllotoxin Derivatives Description Topoisomerase inhibitor that causes DNA strand breaks and cell cycle arrestIV formulations used as part of combination therapy for refractory testicular tumors and as first-line treatment for small-cell lung cancer (SCLC); oral formulation used as first-line treatment for SCLC…

Brands Classes DEA Class; Rx Common Brand Names; Platinol, Platinol -AQ Antineoplastics, Alkylating;  Antineoplastics, Platinum Analog Description Non-cell-cycle specific alkylating agentUsed for the treatment of advanced testicular cancer, advanced ovarian cancer, and advanced bladder cancer, as well as many off-label indicationsCan cause severe nephrotoxicity; ensure adequate hydration and closely monitor renal function and serum electrolytes…

Brands Classes DEA Class; Rx Common Brand Names; Kyprolis Antineoplastics, Proteasome Inhibitors Description Proteasome inhibitorUsed for the treatment of relapsed or refractory multiple myeloma as a single-agent and in combination with other anti-myeloma therapiesThromboprophylaxis is recommended in patients who receive carfilzomib as part of combination therapy Indications Indicated for relapsed or refractory multiple myeloma in…

Brands Classes DEA Class; Rx Common Brand Names; Paraplatin Antineoplastics, Alkylating;  Antineoplastics, Platinum Analog Description Platinum alkylating antineoplastic agent; on a molar basis, carboplatin is 45 times less cytotoxic than cisplatin; as effective as cisplatin in ovarian, non-small cell and small cell lung cancers; not recommended for routine treatment of testicular or head and neck…

Brands Classes DEA Class; Rx Common Brand Names; Velcade Antineoplastics, Proteasome Inhibitors Description A proteasome inhibitor; administered intravenously or subcutaneouslyUsed for the treatment of multiple myeloma and mantle cell lymphomaPatients with pre-existing severe neuropathy should receive bortezomib only after careful risk-benefit assessment Indications Indicated for treatment of patients with mantle cell lymphoma as first-line in…

Brands Classes DEA Class; Rx Common Brand Names; Zytiga, Yonsa Antineoplastics, Antiandrogen Description 17 alpha-hydroxylase/C17,20-lyase (CYP17) inhibitor that blocks androgen biosynthesisUsed in combination with a corticosteroid for the treatment of metastatic castration-resistant prostate cancer2 formulations (Zytiga and Yonsa) have different dosing recommendations and different food effects; do not substitute one for the other Indications Indicated…